{ "schema_version": 1, "kind": "condition", "id": "acute-bronchitis", "name": "Acute Bronchitis (Uncomplicated Adult)", "category": "infectious", "sources": "Egyptian National Drug Formulary - Respiratory 2026 (ambroxol monograph) · Egyptian National Drug Formulary - Respiratory System 2026 (dextromethorphan monograph) · NICE Guideline NG138: Cough (acute) 2019 · UK eMC Paracetamol 500mg Tablets / Suspension SmPC (or DailyMed Acetaminophen Package Insert)", "review_status": "reviewed", "verified_against": "Egyptian National Drug Formulary - Respiratory 2026 (ambroxol monograph) · Egyptian National Drug Formulary - Respiratory System 2026 (dextromethorphan monograph) · UK eMC Paracetamol 500mg Tablets / Suspension SmPC (or DailyMed Acetaminophen Package Insert) · Acute Bronchitis - disease-level clinical article (acute-bronchitis-clinical.txt)", "verified_date": "2026-08", "treatments": [ { "id": 35, "generic": "Referral & safety-netting (no drug therapy)", "line": 1, "is_adjunct": false, "form": null, "strength_mg": null, "adult_dose": null, "adult_duration": null, "dose_source": "Acute Bronchitis - disease-level clinical article (acute-bronchitis-clinical.txt)", "rationale": "Carries the referral criteria and warning signs for this condition, which apply whichever treatment is chosen.", "cautions": [ "RED FLAG - The criteria for chest X-ray to exclude pneumonia are heart rate >100, respiratory rate >24, temperature >38°C, and egophony/fremitus." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": null, "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [], "condition_id": "acute-bronchitis" }, { "id": 33, "generic": "Dextromethorphan", "line": 1, "is_adjunct": true, "form": "oral.solid", "strength_mg": 15.0, "adult_dose": "10-20 mg every 4-6 hours as needed for a dry cough (maximum 80 mg in 24 hours)", "adult_duration": null, "dose_source": "Egyptian National Drug Formulary - Respiratory System 2026 (dextromethorphan monograph)", "rationale": "Centrally acting cough suppressant added for troublesome dry cough; it relieves the symptom only, does not treat the underlying viral infection, and should be avoided if the cough is still productive and clearing sputum.", "cautions": [ "Do not suppress productive cough where clearance of sputum is necessary.", "May cause mild somnolence or dizziness.", "Contraindicated in patients taking monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping such treatment." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Syrup is contraindicated under 6 years and tablets under 12 years. Child 6-11 years: 5 mL of syrup up to four times daily.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "6 to 11 years", "age_min_months": 72, "age_max_months": 143, "dose_text": "5 mL of the syrup up to four times daily. The syrup is contraindicated under 6 years and the tablets under 12 years." } ], "peds_doses": null, "brands": [ { "trade_name": "TUSSILAR 10 MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 2.85, "pack_count": 20, "unit_price": 0.14, "strength_mg": 10.0, "exact_strength": false, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CODIPHAN 10MG/5ML SYRUP 120ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL NILE.", "price_egp": 10.0, "pack_count": null, "unit_price": null, "strength_mg": 10.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "acute-bronchitis" }, { "id": 34, "generic": "Ambroxol", "line": 3, "is_adjunct": true, "form": "oral.solid", "strength_mg": 30.0, "adult_dose": "Immediate release (tablet, syrup or solution): 60-120 mg/day in 2 to 3 divided doses. Extended-release capsule: 75 mg once daily", "adult_duration": null, "dose_source": "Egyptian National Drug Formulary - Respiratory 2026 (ambroxol monograph)", "rationale": "19 live products, and one of the most-dispensed cough preparations in Egypt. The formulary's oral indication is acute and chronic respiratory tract disorders with pathologically thickened mucus and impaired mucus transport. Included so a search does not come back empty, with the evidence limitation stated in the cautions.", "cautions": [ "Acute bronchitis is viral and self-limiting. A mucolytic does not shorten it, and antibiotics are not indicated - the honest treatment is reassurance that a post-viral cough lasts 2-3 weeks.", "The evidence of benefit is modest and comes mainly from studies in chronic productive cough, not acute bronchitis.", "Rare but serious skin reactions have been reported with ambroxol - Stevens-Johnson syndrome, erythema multiforme and acute generalised exanthematous pustulosis. Stop at the first rash.", "The buccal spray and lozenges are local anaesthetics for sore throat - a different indication at a different dose from the oral mucolytic.", "Do not combine with the dextromethorphan already listed in the same row - suppressing a cough while thinning the sputum works against itself." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Children 2-6 years: 7.5 mg three times daily. Children 6-12 years: 15 mg two to three times daily. Infants: the monograph gives 1.2-1.6 mg/kg without specifying per dose or per day, so the numeric fields are left null rather than guessed. Not for children under 2 years.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "2 to 6 years", "age_min_months": 24, "age_max_months": 71, "dose_text": "7.5 mg three times daily" }, { "label": "6 to 12 years", "age_min_months": 72, "age_max_months": 155, "dose_text": "15 mg two to three times daily" } ], "peds_doses": null, "brands": [ { "trade_name": "MUCOSOLVAN 30MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CID > SANOFI", "price_egp": 14.0, "pack_count": 20, "unit_price": 0.7, "strength_mg": 30.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MUCOSOLVAN 15MG/5ML SYRUP 100ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CID > SANOFI", "price_egp": 8.0, "pack_count": null, "unit_price": null, "strength_mg": 15.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "PULMOSOLVAN 15MG/5ML SYRUP 100ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CID", "price_egp": 8.0, "pack_count": null, "unit_price": null, "strength_mg": 15.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "acute-bronchitis" } ] }