# Acute gastroenteritis

- Category: infectious
- Review status: reviewed (every claim checked against a document named on this page)
- Sources: DailyMed Alinia (nitazoxanide) Tablet / Oral Suspension Package Insert, SetID 8d9b1580-0a25-4c07-9b24-4f9640989d25 · DailyMed Zinc Sulfate Tablet / Supplement Package Insert (DailyMed, NLM) · Egyptian National Drug Formulary - Antimicrobial 2023 (ciprofloxacin monograph) · Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (loperamide monograph) · Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (ondansetron monograph) · IMCI Guidelines Egypt 2020 · MSF Essential Drugs 2024 - paracetamol (oral) · WHO Management of Acute Diarrhoea 2019 · WHO. The treatment of diarrhoea: a manual for physicians and other senior health workers, 4th rev. Geneva: WHO; 2005 · WHO. The treatment of diarrhoea: a manual for physicians and other senior health workers, 4th rev. Geneva: WHO; 2005 (IRIS 10665/43209), section 4.3.1 and Table 2
- Verified date: 2026-08

## Verified against

- DailyMed Alinia (nitazoxanide) Tablet / Oral Suspension Package Insert, SetID 8d9b1580-0a25-4c07-9b24-4f9640989d25
- DailyMed Zinc Sulfate Tablet / Supplement Package Insert (DailyMed, NLM)
- Egyptian National Drug Formulary - Antimicrobial 2023 (ciprofloxacin monograph)
- Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (loperamide monograph)
- Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (ondansetron monograph)
- MSF Essential Drugs 2024 - paracetamol (oral)
- WHO. The treatment of diarrhoea: a manual for physicians and other senior health workers, 4th rev. Geneva: WHO; 2005

## Treatment metadata

- Zinc sulphate — 20 mg — oral.solid
- Ondansetron — 4 mg — oral.solid
- Nitazoxanide — 500 mg — oral.solid
- Ciprofloxacin — 500 mg — oral.solid
- ORS — oral.solution
- Paracetamol — 500 mg — oral.solid
- Loperamide — 2 mg — oral.solid

## Complete treatment card

```text
ACUTE GASTROENTERITIS
Sources: DailyMed Alinia (nitazoxanide) Tablet / Oral Suspension Package Insert, SetID
         8d9b1580-0a25-4c07-9b24-4f9640989d25 · DailyMed Zinc Sulfate Tablet / Supplement Package
         Insert (DailyMed, NLM) · Egyptian National Drug Formulary - Antimicrobial 2023
         (ciprofloxacin monograph) · Egyptian National Drug Formulary - Gastrointestinal Tract 2025
         (loperamide monograph) · Egyptian National Drug Formulary - Gastrointestinal Tract 2025
         (ondansetron monograph) · IMCI Guidelines Egypt 2020 · MSF Essential Drugs 2024 -
         paracetamol (oral) · WHO Management of Acute Diarrhoea 2019 · WHO. The treatment of
         diarrhoea: a manual for physicians and other senior health workers, 4th rev. Geneva: WHO;
         2005 · WHO. The treatment of diarrhoea: a manual for physicians and other senior health
         workers, 4th rev. Geneva: WHO; 2005 (IRIS 10665/43209), section 4.3.1 and Table 2
Review status: REVIEWED against 6 sources listed above  (2026-08)

IS IT THIS? - reference only, to read alongside your own examination
  SYMPTOMS - what the patient reports (9)
    - Loose or watery stools at least three times in a day  [diarrhoea]
    - Nausea, vomiting, fever or belly pain may come with it  [abdominal pain · fever · nausea ·
      vomiting]
    - Usually settles inside a week, often better after one to three days
    - Anything still going past two weeks is chronic and not this
    - Onset is fairly sudden, building over one or two hours
    - Family members or close contacts often report the same trouble
    - Low-grade fever and mild belly pain are usual; most but not all vomit  [abdominal pain ·
      fever]
    - High fever, bloody stools, relentless vomiting or severe belly pain point away from a viral
      cause  [abdominal pain · bloody diarrhoea · diarrhoea · fever · vomiting]
    - Ask about travel, recent antibiotics, exposures at work and immune status
  SIGNS - what you find (5)
    - Mild fever is usual, but >39 °C should raise concern for a non-viral cause  [fever]
    - Fast pulse and fast breathing can follow the fever and fluid loss  [fever · tachypnoea]
    - Judging dehydration matters most at the extremes of age or in chronic illness  [dehydration]
    - The belly is mildly and diffusely tender
    - Marked tenderness, guarding, rebound or one tender spot should send you looking elsewhere
      [guarding · rebound tenderness]
  TESTS (7)
    - Diagnosis is clinical; viral testing is rarely to hand
    - Blood count may show mild leukocytosis, with inflammatory markers slightly up
    - Heavy fluid loss shows as haemoconcentration and electrolyte upset
    - Rising urea and creatinine mean the kidneys have taken a hit
    - Abdominal imaging is usually normal; CT may show mild diffuse colonic wall thickening
    - Stool assays in most labs find bacteria only, not the virus
    - Send stool when there is blood, high fever, severe pain or heavy dehydration
  IF NOT THIS - what else fits (6)
    - Food poisoning from bacterial toxins mimics it closely
    - Bacterial and protozoal gastroenteritis look alike but need other treatment and carry more
      risk
    - Salmonella, E coli, Shigella, Campylobacter, Giardia and C difficile when the picture is
      atypical
    - Appendicitis, diverticulitis, inflammatory bowel disease, obstruction or cholecystitis
    - Missed abdominal pathology is often first labelled gastroenteritis
    - Viral upper respiratory illness and some bacterial pneumonias can look the same
  Score   WHO dehydration classification (child with diarrhoea) - How dehydrated is this child, and
          which rehydration plan?
  Source  StatPearls "Viral Gastroenteritis" - disease-level clinical article
  Status  traced to the source above

Rx: Zinc  |  Vomiting  |  If parasitic  |  If bacterial dysentery  |  Rehydration  |  Pain and fever
    |  Anti-diarrhoeal

ZINC
1. ZINC SULPHATE                                          [1st line]
   Adult    Not established by WHO for adult gastroenteritis; adult dietary supplement dosing is
            typically 15-50 mg daily of elemental zinc. x 10-14 days
   Peds     Under 6 months: 10 mg daily for 10 to 14 days
            6 months and over: 20 mg daily for 10 to 14 days
            (10 mg/day under 6 months, 20 mg/day from 6 months, for 10-14 days)
   Source   DailyMed Zinc Sulfate Tablet / Supplement Package Insert (DailyMed, NLM)
   Why      Zinc supplementation supports gut mucosal repair and immune function during and after
            diarrheal illness; recommended by WHO as a companion to oral rehydration to shorten the
            episode and reduce recurrence, not as a substitute for fluids.
   Caution  Give full 10-14 day course even after diarrhea stops.
            May cause mild nausea or abdominal discomfort.
            Zinc sulphate is a WHO recommended adjunct that reduces duration and severity.
   Egypt    ZINCOSAFE 11 MG 100 CAPS.        SAFE PHARMA         50.00 EGP (0.50/unit)
                -> ? strength differs
            ZINC STRONG 20 CAPS.             NAPCO               29.00 EGP (1.45/unit)
                -> ? strength differs
            ARABZINC 50 MG 30 TABS.          ARAB CAPS > K...    45.00 EGP (1.50/unit)
                -> ? strength differs
            GREEN & LEAN ZINC 50 MG 30 CAPS. > ALTONA HEALTH     48.00 EGP (1.60/unit)
                -> ? strength differs
            MONO ZINC 20 F.C. TABS.          ARAB CAPS > B...    41.25 EGP (2.06/unit)
                -> ? strength differs
            ALL ONE ZINC 50 MG 30 TABS.      MOZN PHARMACE...    80.00 EGP (2.67/unit)
                -> ? strength differs
            OCTOZINC 25 MG 100*10 CAPS.      OCTOBER PHARMA     850.00 EGP (85.00/unit)
                -> ? strength differs
            ZINC PICOLINATE 50 MG 120 VEG. CAPS. (NOW) NOW FOODS > SOFICOPHARM           1300.00 EGP
                -> ? strength differs
            ZINC SULFATE 10MG/5ML POWDER FOR SYRUP CID                                      5.00 EGP
                -> ? strength differs, ? different route - not oral solid
            ZINC-SEDICO 10MG/5ML PD. FOR ORAL SOL. SEDICO                                   7.00 EGP
                -> ? strength differs, ? different route - not oral solid


VOMITING
2. ONDANSETRON                                            [2nd line]
   Adult    4-8 mg single oral dose for persistent vomiting preventing rehydration - single-dose
   Peds     0.15 mg/kg/dose  [child max 8 mg]
            (Single oral dose to facilitate oral rehydration)
            3kg -> 0.45 mg/dose  4kg -> 0.6 mg/dose   5kg -> 0.75 mg/dose  6kg -> 0.9 mg/dose
            7kg -> 1.1 mg/dose   8kg -> 1.2 mg/dose   9kg -> 1.3 mg/dose   10kg -> 1.5 mg/dose
            11kg -> 1.6 mg/dose  12kg -> 1.8 mg/dose  13kg -> 1.9 mg/dose  14kg -> 2.1 mg/dose
            15kg -> 2.2 mg/dose  16kg -> 2.4 mg/dose  17kg -> 2.5 mg/dose  18kg -> 2.7 mg/dose
            19kg -> 2.9 mg/dose  20kg -> 3 mg/dose    21kg -> 3.1 mg/dose  22kg -> 3.3 mg/dose
            23kg -> 3.4 mg/dose  24kg -> 3.6 mg/dose  25kg -> 3.8 mg/dose  26kg -> 3.9 mg/dose
            27kg -> 4 mg/dose    28kg -> 4.2 mg/dose  29kg -> 4.3 mg/dose  30kg -> 4.5 mg/dose
            31kg -> 4.6 mg/dose  32kg -> 4.8 mg/dose  33kg -> 5 mg/dose    34kg -> 5.1 mg/dose
            35kg -> 5.2 mg/dose  36kg -> 5.4 mg/dose  37kg -> 5.5 mg/dose  38kg -> 5.7 mg/dose
            39kg -> 5.8 mg/dose  40kg -> 6 mg/dose    41kg -> 6.1 mg/dose  42kg -> 6.3 mg/dose
            43kg -> 6.5 mg/dose  44kg -> 6.6 mg/dose  45kg -> 6.8 mg/dose  46kg -> 6.9 mg/dose
            47kg -> 7 mg/dose    48kg -> 7.2 mg/dose  49kg -> 7.3 mg/dose  50kg -> 7.5 mg/dose
   Source   Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (ondansetron monograph)
   Why      Antiemetic that blocks the serotonin receptors driving the vomiting reflex, used to
            control vomiting so that oral rehydration can succeed instead of failing and requiring
            intravenous fluids.
   Caution  Do not give repeated doses due to risk of masking surgical abdomen.
            The formulary's ondansetron dosing covers chemotherapy and radiotherapy nausea, where
            the adult dose is 8 mg. Use in acute gastroenteritis is a lower dose for a different
            purpose - enabling oral rehydration - and is not a licensed indication in the formulary.
            A single dose only is given in the acute setting to allow oral rehydration, and multiple
            doses carry a risk of QT prolongation.
   Egypt    DANOFRAN 4MG 5 F.C. TAB.         UP PHARMA           70.00 EGP (14.00/unit)
            SETRONOMET 4 MG 4 ORAL DIS. TABS. AVERROES PHARMA                              78.00 EGP
            IDIVOMTRON 4 MG 10 ORALLY DIS. TABS. INTERNATIONAL DRUG AGENCY (IDI)          144.00 EGP
            EMEREST 4 MG 10 ORO-DISPERSIBLE TABS. GLOBAL PHARMACEUTICAL INDUSTRIES        188.00 EGP
            IDIVOMTRON 4 MG/5ML SYRUP 50 ML  RAMEDA > INTE...   110.00 EGP
                -> ? strength differs, ? different route - not oral solid


IF PARASITIC
3. NITAZOXANIDE                                           [2nd line]
   Adult    500 mg orally twice daily with food x 3 days
   Peds     Nitazoxanide tablets should not be administered to pediatric patients 11 years of age or
            younger because a single tablet contains a greater amount of nitazoxanide than the
            recommended dosing in this pediatric age group.
   Source   DailyMed Alinia (nitazoxanide) Tablet / Oral Suspension Package Insert, SetID
            8d9b1580-0a25-4c07-9b24-4f9640989d25
   Why      Broad-spectrum antiparasitic and antiprotozoal agent used as a second-line option when
            gastroenteritis is persistent or a less common pathogen is suspected.
   Caution  Take with food.
            Urine discoloration may occur.
            Nitazoxanide is a broad spectrum agent for persistent gastroenteritis.
   Egypt    UNINITAPROZAX 500MG 12 F.C. TAB. UNIPHARMA CO....    16.00 EGP (1.33/unit)
            CRYPTOPER 500MG 30 F.C. TAB.     EGPI > TAG PH...    56.00 EGP (1.87/unit)
            XEROVIRINC 500MG 18 F.C. TAB.    MINA PHARM          42.00 EGP (2.33/unit)
            PARAZOXANIDE 500 MG 18 CAP.      MISR > PHARMA...    63.00 EGP (3.50/unit)
            TRUSTNAL 500 MG 10 F.C. TABS.    ADWIA               40.00 EGP (4.00/unit)
            NIT CLEAN 500MG 12 F.C. TABS.    WESTERN PHARM...    72.00 EGP (6.00/unit)
            CRYPTONAZ 500MG 12 F.C.TAB.      COPAD PHARMA        82.00 EGP (6.83/unit)
            NIT CLEAN 500MG 5*6 F.C. TABS.   WESTERN PHARM...   180.00 EGP (30.00/unit)
            UNINITAPROZAX 100MG/5ML SUSP. 60ML UNIPHARMA CO. > UNIPHARMA                    6.00 EGP
                -> ? strength differs, ? different route - not oral solid
            ZOLIFUTAL 100MG/5ML SUSP. 60 ML  FUTURE PHARMA...    13.50 EGP
                -> ? strength differs, ? different route - not oral solid


IF BACTERIAL DYSENTERY
4. CIPROFLOXACIN                                          [2nd line]
   Adult    500 mg every 12 hours - bloody diarrhoea only x 3 days
   Peds     10-15 mg/kg/dose  [child max 500 mg]
            (10-15 mg/kg per dose twice daily for 3 days, maximum 500 mg per
            dose. The low end and the per-dose maximum are the Egyptian
            formulary's general paediatric dosing for mild to moderate
            infection; the 15 mg/kg figure and the 3-day duration are WHO's
            dysentery regimen.)
            3kg -> 30-45 mg/dose                    4kg -> 40-60 mg/dose
            5kg -> 50-75 mg/dose                    6kg -> 60-90 mg/dose
            7kg -> 70-105 mg/dose                   8kg -> 80-120 mg/dose
            9kg -> 90-135 mg/dose                   10kg -> 100-150 mg/dose
            11kg -> 110-165 mg/dose                 12kg -> 120-180 mg/dose
            13kg -> 130-195 mg/dose                 14kg -> 140-210 mg/dose
            15kg -> 150-225 mg/dose                 16kg -> 160-240 mg/dose
            17kg -> 170-255 mg/dose                 18kg -> 180-270 mg/dose
            19kg -> 190-285 mg/dose                 20kg -> 200-300 mg/dose
            21kg -> 210-315 mg/dose                 22kg -> 220-330 mg/dose
            23kg -> 230-345 mg/dose                 24kg -> 240-360 mg/dose
            25kg -> 250-375 mg/dose                 26kg -> 260-390 mg/dose
            27kg -> 270-405 mg/dose                 28kg -> 280-420 mg/dose
            29kg -> 290-435 mg/dose                 30kg -> 300-450 mg/dose
            31kg -> 310-465 mg/dose                 32kg -> 320-480 mg/dose
            33kg -> 330-495 mg/dose                 34kg -> 340-500 mg/dose (upper capped)
            35kg -> 350-500 mg/dose (upper capped)  36kg -> 360-500 mg/dose (upper capped)
            37kg -> 370-500 mg/dose (upper capped)  38kg -> 380-500 mg/dose (upper capped)
            39kg -> 390-500 mg/dose (upper capped)  40kg -> 400-500 mg/dose (upper capped)
            41kg -> 410-500 mg/dose (upper capped)  42kg -> 420-500 mg/dose (upper capped)
            43kg -> 430-500 mg/dose (upper capped)  44kg -> 440-500 mg/dose (upper capped)
            45kg -> 450-500 mg/dose (upper capped)  46kg -> 460-500 mg/dose (upper capped)
            47kg -> 470-500 mg/dose (upper capped)  48kg -> 480-500 mg/dose (upper capped)
            49kg -> 490-500 mg/dose (upper capped)  50kg -> 500 mg/dose (capped)
   AWaRe    WATCH group - carries resistance cost. Egyptian EML 2025.
   Source   Egyptian National Drug Formulary - Antimicrobial 2023 (ciprofloxacin monograph)
   Why      The Egyptian EML 2025 names ciprofloxacin the first choice for acute invasive bacterial
            diarrhoea / dysentery, and the WHO pocket book gives 15 mg/kg twice a day for 3 days for
            a child with dysentery when sensitivity is unknown. The adult figure of 500 mg every 12
            hours is the formulary's tabulated GI dose; the 3-day duration is WHO's.
   Caution  For bloody diarrhoea with fever only. Most acute gastroenteritis is viral and needs ORS
            and zinc, not this.
            Watch group on the Egyptian EML - do not use it for watery diarrhoea.
            Quinolone class risks: tendinitis and tendon rupture, QT prolongation, glycaemic swings.
            Antacids, iron, calcium and zinc block absorption - and zinc is being given in this same
            condition, so separate them by 2 hours.
            Not routinely first-line in children; the formulary says use it after weighing risks and
            benefits.
   Egypt    QUINOLOROX 500MG 10 F.C. TAB.    EPCI > ROXXEN       10.00 EGP (1.00/unit)
            ECACIPROFLOX 500 MG 20 F.C. TABS. FUTURE PHARMACEUTICAL INDU...    27.00 EGP (1.35/unit)
            ELMODOXACIN 500MG 10 F.C.TAB.    EGPI > SEA PHARM    20.00 EGP (2.00/unit)
            CIPROQUIN 500MG 10 F.C. TAB.     UNIPHARMA           50.00 EGP (5.00/unit)
            CIPROFLOXACIN-ORGANO 500 MG 10 F.C.TABS. ORGANOPHARMA > ORGANO     63.00 EGP (6.30/unit)
            CIPROFAR 500MG 10 F.C.TAB.       PHARCO              69.00 EGP (6.90/unit)
            CIPROMEGA XL 500MG 10 EXT. REL. F.C.TABS. MASH PREMIERE                        48.00 EGP
            HEROXACIN 500MG 10 SCORED F.C. TAB. EGPI > HERO PHARM                          69.00 EGP


REHYDRATION - give alongside
5. ORS                                                    [add-on - not a substitute]
   Adult    Plan A (no dehydration): Drink as much fluid/ORS as desired after each loose stool. Plan
            B (some dehydration): 2,200 to 4,000 mL over the first 4 hours. x 3-5 days
   Peds     Under 2 years: 50 to 100 mL of ORS after each loose stool (Plan A, no dehydration). With
            some dehydration, Plan B is by weight at any age.
            2 to 10 years: 100 to 200 mL of ORS after each loose stool (Plan A, no dehydration).
            With some dehydration, Plan B is by weight at any age.
            (Plan B (some dehydration): weight (kg) x 75 mL ORS over first 4 hours, then reassess.
            Plan A (no dehydration): 50-100 mL after each loose stool under 2 years, 100-200 mL from
            2 to 10 years.)
   Source   WHO. The treatment of diarrhoea: a manual for physicians and other senior health
            workers, 4th rev. Geneva: WHO; 2005
   Why      Oral rehydration solution replaces the fluid and electrolytes lost through diarrhea and
            vomiting, which is what prevents dehydration; supportive rehydration rather than
            treatment of the underlying infection, and given alongside zinc rather than instead of
            it.
   Caution  Given WITH the other, not instead of it. WHO pairs oral rehydration and zinc for
            childhood diarrhoea - the fluid keeps the child alive and the zinc shortens the illness
            and reduces the next one.
            Dissolve 1 sachet in clean water.
            Does not stop diarrhea but replaces lost fluid and electrolytes.
            Oral rehydration salts are the mainstay of acute gastroenteritis and prevent
            dehydration.
   Egypt    GLUCOHYDRAN 10 SACHET.           ARAB DRUG COM...     1.75 EGP
            REHYDRAN N 10 SACHET             CID                  4.50 EGP
            REHYDRO ZINC 10 SACHETS          CID                  7.00 EGP
            ORS 20 SACHETS                   PHAROPHARMA         40.00 EGP
            ELECTRO MASH SYRUP 200 ML        MASH PREMIERE       60.00 EGP
            FLEXOLYTE ORAL REHYDRATION SOL. 240 ML KEMPETRO FOR CHEMICAL INDUSTRIES        65.00 EGP
            HERO ORS 200 ML                  HERO > HERO M...   120.00 EGP
            SANSO ORS SYRUP 140 ML           AUG PHARMA         400.00 EGP


PAIN AND FEVER - give alongside
6. PARACETAMOL                                            [add-on - not a substitute]
   Adult    1 g three or four times daily, maximum 4 g in 24 hours - while febrile, usually 1-3 days
   Peds     15 mg/kg/dose  [child max 500 mg]
            (Child 1 month and over: 15 mg/kg 3 or 4 times daily (max. 60
            mg/kg daily))
            3kg -> 45 mg/dose                 4kg -> 60 mg/dose
            5kg -> 75 mg/dose                 6kg -> 90 mg/dose
            7kg -> 105 mg/dose                8kg -> 120 mg/dose
            9kg -> 135 mg/dose                10kg -> 150 mg/dose
            11kg -> 165 mg/dose               12kg -> 180 mg/dose
            13kg -> 195 mg/dose               14kg -> 210 mg/dose
            15kg -> 225 mg/dose               16kg -> 240 mg/dose
            17kg -> 255 mg/dose               18kg -> 270 mg/dose
            19kg -> 285 mg/dose               20kg -> 300 mg/dose
            21kg -> 315 mg/dose               22kg -> 330 mg/dose
            23kg -> 345 mg/dose               24kg -> 360 mg/dose
            25kg -> 375 mg/dose               26kg -> 390 mg/dose
            27kg -> 405 mg/dose               28kg -> 420 mg/dose
            29kg -> 435 mg/dose               30kg -> 450 mg/dose
            31kg -> 465 mg/dose               32kg -> 480 mg/dose
            33kg -> 495 mg/dose               34kg -> 500 mg/dose (capped)
            35kg -> 500 mg/dose (capped)      36kg -> 500 mg/dose (capped)
            37kg -> 500 mg/dose (capped)      38kg -> 500 mg/dose (capped)
            39kg -> 500 mg/dose (capped)      40kg -> 500 mg/dose (capped)
            41kg -> 500 mg/dose (capped)      42kg -> 500 mg/dose (capped)
            43kg -> 500 mg/dose (capped)      44kg -> 500 mg/dose (capped)
            45kg -> 500 mg/dose (capped)      46kg -> 500 mg/dose (capped)
            47kg -> 500 mg/dose (capped)      48kg -> 500 mg/dose (capped)
            49kg -> 500 mg/dose (capped)      50kg -> 500 mg/dose (capped)
   Source   MSF Essential Drugs 2024 - paracetamol (oral)
   Why      The WHO diarrhoea chapter says to give paracetamol if the child has a distressing fever
            of 39 C or more - and to consider severe bacterial infection at the same time. The dose
            is the MSF drug reference's.
   Caution  A high fever in a child with diarrhoea is WHO's cue to consider severe bacterial
            infection - treat the fever and reassess the child, do not just treat the fever.
            Paracetamol rather than an NSAID: the child is fluid-depleted, and NSAIDs are
            nephrotoxic in dehydration.
            Check other products for paracetamol content.
            Reduce the maximum in liver disease or severe acute malnutrition.
            500 mg is the per-dose ceiling used here for a child. 1000 mg is the adult dose and does
            not belong in a weight calculation - the daily 60 mg/kg limit is the one that binds
            first in any case.
   Egypt    FEBRIMOL 500 MG 20 TAB.          PHARCO               3.50 EGP (0.17/unit)
            CETAMOL 500 MG 20 TABS.          MEMPHIS              8.00 EGP (0.40/unit)
            PARACETAMOL-MUP 500MG B.P. 20 TABS. MUP                            13.00 EGP (0.65/unit)
            CETAL 500 MG 20 TABS.            EIPICO              24.00 EGP (1.20/unit)
            ARKADOLOW 500 MG 30 F.C. TABS.   UTOPIA              42.00 EGP (1.40/unit)
            PARAMOL 500MG 20 TAB.            MISR                38.00 EGP (1.90/unit)
            ADOL 500MG 24 CAPLETS            JULPHAR             32.00 EGP
            AUGICETAMIDE 500 MG 20 SACHETS   AUG PHARMA          50.00 EGP
            FEBRIMOL ORAL DROPS 20 ML        PHARCO               4.00 EGP
                -> ? strength differs, ? different route - not oral solid
            THERA-LO 3.2G/100ML ORAL SUSP. 100 ML PHAROPHARMA                               5.00 EGP
                -> ? strength differs, ? different route - not oral solid


ANTI-DIARRHOEAL - give alongside
7. LOPERAMIDE                                             [add-on - not a substitute]
   Adult    4 mg initially, then 2 mg after each loose stool; maximum 12-16 mg in 24 hours x up to 2
            days
   Peds     Some have dangerous, and sometimes fatal, side-effects. These drugs should never be
            given to children below 5
   Source   Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (loperamide monograph)
   Why      Loperamide is on the Egyptian EML 2025 under medicines for diarrhoea, and the Egyptian
            formulary's own indication is symptomatic treatment of acute diarrhoea in adults and
            children 12 years and over. It is the drug an adult is actually asking for when they
            have to travel or work.
   Caution  Contraindicated in acute dysentery - blood in the stools with high fever - and in
            invasive bacterial enteritis (Salmonella, Shigella, Campylobacter).
            Contraindicated in abdominal pain without diarrhoea, in acute ulcerative colitis, and in
            antibiotic-associated colitis.
            It does not replace fluid. ORS remains the priority even while it is being taken.
            Stop and reassess if diarrhoea lasts more than 2 days, or if the abdomen distends.
            Above the recommended dose it prolongs the QT interval and has caused fatal arrhythmia;
            it is also misused as an opioid substitute.
   Egypt    MOTIJUST 2 MG 30 CAPS            INTERNATIONAL...    27.00 EGP (0.90/unit)
            STOPRRHEA 2 MG 10 ORODISPERSIBLE TABS. WESTERN PHARMACEUTICALS INDUSTRIE...    10.00 EGP
            IMODIUM INSTANT 2MG 6 ORODISPERSIBLE TABS. MCNEIL PRODUCTS LTD. > JOHNSO...    80.00 EGP
            STOPRRHEA 2 MG 30 ORODISPERSIBLE TABS. WESTERN PHARMACEUTICALS INDUSTRIE...    96.00 EGP

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.
```

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