{ "schema_version": 1, "kind": "condition", "id": "atopic-eczema-adult", "name": "Atopic Eczema in Adults", "category": "chronic", "sources": "Betamethasone Valerate 0.1%w/w Cream SmPC section 4.2 Posology and method of administration (eMC product 102491) · Eumovate (clobetasone butyrate 0.05%) Cream SmPC sections 4.2 and 4.4 (eMC product 3807) · Hydrocortisone 1% cream SmPC section 4.2 (eMC product 13103) · NICE CKS: Eczema - atopic 2025 · NICE Technology Appraisal TA82: Tacrolimus and Pimecrolimus for Atopic Eczema 2004 · No labelled dose - emollient applied liberally and as often as needed, to effect · Protopic 0.1% ointment SmPC sections 4.1 and 4.2 (eMC product 1608)", "review_status": "reviewed", "verified_against": "Betamethasone Valerate 0.1%w/w Cream SmPC section 4.2 Posology and method of administration (eMC product 102491) · Eumovate (clobetasone butyrate 0.05%) Cream SmPC sections 4.2 and 4.4 (eMC product 3807) · Hydrocortisone 1% cream SmPC section 4.2 (eMC product 13103) · No labelled dose - emollient applied liberally and as often as needed, to effect · Protopic 0.1% ointment SmPC sections 4.1 and 4.2 (eMC product 1608)", "verified_date": "2026-08", "treatments": [ { "id": 209, "generic": "Liquid paraffin", "line": 1, "is_adjunct": false, "form": "topical", "strength_mg": null, "adult_dose": "Apply emollient liberally and frequently (at least 2-3 times daily) to all skin, including areas that are currently clear", "adult_duration": "long-term continuous maintenance", "dose_source": "No labelled dose - emollient applied liberally and as often as needed, to effect", "rationale": "Emollients remain the foundation of adult eczema management and reduce the amount of topical corticosteroid needed", "cautions": [ "Continue emollient use even when skin is clear to maintain barrier function.", "Apply emollient 15-30 minutes before or after a topical steroid, not at the same time.", "Warn about fire hazard when fabric contacts paraffin-based products.", "Use a soap substitute rather than standard soap." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Not applicable in this adult entry - see 'Atopic Eczema in Children' for paediatric dosing", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "ADCOCARE CREAM 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 12.0, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "glyceryl monostearate, propylene glycol, urea" }, { "trade_name": "DERMOLAN CREAM 50 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "HI-CARE > EMICO PHARMA", "price_egp": 19.0, "pack_count": null, "unit_price": null, "strength_mg": 50000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "allantoin, glycerol, glycolic acid, panthenol, salicylic acid, urea, vitamin c, zinc oxide" }, { "trade_name": "ADCOCARE CREAM 40 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 21.75, "pack_count": null, "unit_price": null, "strength_mg": 40000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "glyceryl monostearate, propylene glycol, urea" }, { "trade_name": "CARE MIX PLUS HAIR CREAM 50 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "VITA PHARM > CARE MIX", "price_egp": 29.5, "pack_count": null, "unit_price": null, "strength_mg": 50000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "cetostearyl alcohol, lanolin, panthenol, wheat protein, white soft paraffin" }, { "trade_name": "PROPOLIS CREAM 15 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "LUNA FOR PERFUMES AND COSMETICS > TECHNOMED GROUP", "price_egp": 30.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "cera alba, glycerin, propolis" }, { "trade_name": "PROPOLIS CREAM 30 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "LUNA FOR PERFUMES AND COSMETICS > TECHNOMED GROUP", "price_egp": 55.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "cera alba, glycerin, propolis" }, { "trade_name": "HEALTHPOINT NAPPY CREAM 100 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "HEALTHPOINT LTD. > PAXTON", "price_egp": 70.0, "pack_count": null, "unit_price": null, "strength_mg": 100000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "benzyl alcohol, cetearyl alcohol, glyceryl stearate, lanolin, peg-100 s, water, zinc oxide" }, { "trade_name": "HERCUL WHITENING CREAM 60 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "LEADER FOR COSMETICS > JUNIER PHARMA", "price_egp": 74.75, "pack_count": null, "unit_price": null, "strength_mg": 60000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "alpha arbutin, diemthicone, glycerin, licorice ext, octyl methoxy, titanium dioxide, vit.c" } ], "condition_id": "atopic-eczema-adult" }, { "id": 210, "generic": "Hydrocortisone", "line": 1, "is_adjunct": false, "form": "topical", "strength_mg": null, "adult_dose": "Adults and children: To be applied sparingly to the affected skin two or three times daily after gently cleansing the area.", "adult_duration": "up to 1-2 weeks, then reassess. The label does not set a number for the face beyond avoiding prolonged use - keep facial courses as short as the flare allows", "dose_source": "Hydrocortisone 1% cream SmPC section 4.2 (eMC product 13103)", "rationale": "Mild potency is reserved for delicate facial and flexural skin; step up to moderate potency for the trunk and limbs if inadequate response", "cautions": [ "Avoid prolonged use on the face - the label says so without naming a number, so the five-day figure often quoted is custom rather than licence. Shortest course that settles it.", "Stop once the flare resolves; do not use as long-term continuous maintenance.", "Watch for secondary bacterial infection (weeping, crusting, pustules) requiring oral flucloxacillin.", "Limit a course in a child to 7-10 days, and remember the face and scalp absorb far more than limb skin.", "Hydrocortisone Cream is contra-indicated in patients with bacterial, viral or fungal infections of the skin. Urticaria, rosacea, ulcers and local infection are also contra-indications." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Not applicable in this adult entry - see 'Atopic Eczema in Children' for paediatric dosing", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "NOVACORTIN 1% CREAM 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 4.75, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NOVACORTIN 1% OINT. 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 4.75, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MICORT 1% CREAM 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MISR", "price_egp": 12.5, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "HYDROCORTISONE 1% OINT. 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MISR", "price_egp": 21.0, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "atopic-eczema-adult" }, { "id": 211, "generic": "Clobetasone", "line": 1, "is_adjunct": false, "form": "topical", "strength_mg": null, "adult_dose": "Apply 0.05% cream/ointment thinly once or twice daily to inflamed skin on the trunk and limbs", "adult_duration": "Up to 4 weeks of continuous daily use; a child should not normally exceed 7 days", "dose_source": "Eumovate (clobetasone butyrate 0.05%) Cream SmPC sections 4.2 and 4.4 (eMC product 3807)", "rationale": "Moderate potency for trunk/limb flares not controlled by mild potency steroid, per the CKS potency ladder", "cautions": [ "Do not use on the face or flexures - reserve moderate potency for the trunk and limbs.", "There is a risk of skin thinning (atrophy) with prolonged or repeated courses.", "Four weeks of continuous daily use is the adult ceiling. In a child it is normally seven days, and under 12 it should be a doctor's decision to use it at all.", "Keep it off the face where you can - facial skin thins faster than anywhere else.", "Under a dressing it absorbs far more and the warm damp underneath breeds bacteria. Clean the skin before each fresh dressing." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Not applicable in this adult entry - see 'Atopic Eczema in Children' for paediatric dosing", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "EUMOVATE 0.05% TOP. CREAM 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 12.75, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "EUMOVATE 0.05% TOP. OINT. 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SMITHKLINE BEECHAM > GLAXO SMITHKLINE", "price_egp": 12.75, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "atopic-eczema-adult" }, { "id": 212, "generic": "Betamethasone", "line": 2, "is_adjunct": false, "form": "topical", "strength_mg": null, "adult_dose": "Apply 0.1% cream/ointment thinly twice daily to affected areas for itch and inflammation", "adult_duration": "Short courses during a flare, usually 1-2 weeks; step back down once the flare settles", "dose_source": "Betamethasone Valerate 0.1%w/w Cream SmPC section 4.2 Posology and method of administration (eMC product 102491)", "rationale": "The potent rung the ladder was missing. Hydrocortisone 1% is mild and clobetasone 0.05% moderate; when a trunk or limb flare does not settle on clobetasone the next step is a potent steroid, not a calcineurin inhibitor. Undertreating a flare with a steroid too weak for it is the commoner failure in eczema, not overtreating.", "cautions": [ "Potent steroid. Not on the face, the eyelids or the flexures - use hydrocortisone 1% there. Potent steroid on facial skin thins it and causes perioral dermatitis.", "Short courses during a flare, then step back down. Continuous potent steroid causes skin atrophy, striae that do not recover, and telangiectasia.", "Fingertip units, not 'a thin smear'. Undertreating a flare is what makes people believe steroids do not work and then use them for longer.", "Do not apply to infected or ulcerated skin. Weeping, crusted or rapidly worsening eczema is usually infected and needs that treated first.", "Keep the emollient going underneath and between flares. The steroid treats the flare; the emollient is what reduces how often flares come." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "This entry is for adults. In a child, a potent steroid on the trunk or limbs is a short, deliberate course - see the childhood eczema entry, and never use a potent steroid on a child's face or flexures.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "CRONOMESONE 0.1% CREAM 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 4.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CRONOMESONE 0.1% OINT. 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 4.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BETNOVATE 0.1% TOP. OINT. 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SMITHKLINE BEECHAM > GLAXO SMITHKLINE", "price_egp": 6.9, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BETADERM 0.1% CREAM 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 18.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BETAVAL 0.1% CREAM 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 20.0, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BETADERM 0.1% CREAM 30 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 23.0, "pack_count": null, "unit_price": null, "strength_mg": 30000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BETAMETHASONE DIPROPIONATE 0.05% CREAM 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AMRIYA", "price_egp": 11.5, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BETAMETHASONE DIPROPIONATE 0.05% OINT. 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AMRIYA", "price_egp": 11.5, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "atopic-eczema-adult" }, { "id": 213, "generic": "Tacrolimus", "line": 2, "is_adjunct": false, "form": "topical", "strength_mg": null, "adult_dose": "Apply 0.1% ointment thinly twice daily to affected areas (the 0.1% strength is licensed for adults only; children use 0.03%)", "adult_duration": "until lesions clear, then maintenance once a day twice weekly; eligibility for maintenance is a response within 6 weeks of twice-daily use", "dose_source": "Protopic 0.1% ointment SmPC sections 4.1 and 4.2 (eMC product 1608)", "rationale": "Second-line, steroid-sparing option for moderate-to-severe eczema not controlled by topical corticosteroids, or where continued steroid use risks skin atrophy, particularly on the face; TA82 recommends initiation only by a clinician with dermatology experience", "cautions": [ "Not first-line and not for mild eczema - reserve for moderate-to-severe disease unresponsive to topical corticosteroids.", "Transient burning or stinging on application is common and usually settles within a few days.", "Avoid sun exposure and use sun protection on treated skin.", "Avoid occlusive dressings over application sites.", "Reconsider the diagnosis and the treatment if there is no improvement after two weeks of twice-daily use.", "A patient on maintenance needs a physician review at 12 months to decide whether to continue." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Not applicable in this adult entry - see 'Atopic Eczema in Children' for paediatric dosing", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "TAROLIMUS 0.1% TOPICAL OINT. 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ANDALOUS PHARMA", "price_egp": 144.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TRECZIMUS 0.1% TOPICAL OINT. 30 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MARCYRL PHARMACEUTICAL INDUSTRIES (MPI)", "price_egp": 219.0, "pack_count": null, "unit_price": null, "strength_mg": 30000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PROTOPIC 0.1 % OINT. 30 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "LEO PHARMACEUTICAL PRODUCTS", "price_egp": 407.0, "pack_count": null, "unit_price": null, "strength_mg": 30000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TRECZIMUS 0.03% TOPICAL OINT. 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MARCYRL PHARMACEUTICAL INDUSTRIES (MPI)", "price_egp": 114.0, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TAROLIMUS 0.03% TOPICAL OINT. 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ANDALOUS PHARMA", "price_egp": 129.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PROTOPIC 0.03 % OINT. 30 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "LEO PHARMACEUTICAL PRODUCTS", "price_egp": 371.0, "pack_count": null, "unit_price": null, "strength_mg": 30000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "atopic-eczema-adult" } ] }