{
  "schema_version": 1,
  "kind": "condition",
  "id": "bartholin-cyst-abscess",
  "name": "Bartholin's Cyst and Abscess",
  "category": "infectious",
  "sources": "CDC Sexually Transmitted Infections Treatment Guidelines 2021 · Egyptian National Drug Formulary - Antimicrobial 2023 · StatPearls: Bartholin Gland Cyst (NCBI Bookshelf NBK532271)",
  "review_status": "reviewed",
  "verified_against": "StatPearls: Bartholin Gland Cyst (NCBI Bookshelf NBK532271) · Egyptian National Drug Formulary - Antimicrobial 2023 · Bartholin Gland Cyst - disease-level clinical article (bartholin-cyst-abscess-clinical.txt)",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 245,
      "generic": "Conservative Management & Surgical Drainage (Primary Care Strategy)",
      "line": 1,
      "is_adjunct": false,
      "form": null,
      "strength_mg": null,
      "adult_dose": "Asymptomatic Bartholin cysts require no treatment. Acute fluctuant Bartholin abscesses require surgical incision and drainage (or Word catheter placement); routine systemic antibiotics are NOT required for simple drained abscesses without surrounding cellulitis or systemic infection.",
      "adult_duration": "Single procedure / observation",
      "dose_source": "StatPearls: Bartholin Gland Cyst (NCBI Bookshelf NBK532271)",
      "rationale": "Incision and drainage is the primary and definitive treatment for Bartholin abscesses; systemic antibiotics provide no benefit for uncomplicated drained abscesses without surrounding cellulitis.",
      "cautions": [
        "Incision and drainage is the primary treatment for fluctuant Bartholin abscesses; systemic antibiotics are indicated only if surrounding cellulitis, systemic infection, or pregnancy is present.",
        "Drainage alone recurs. StatPearls is blunt about it - with incision and drainage only, recurrence rates are unacceptably high - which is the argument for a Word catheter rather than a scalpel and a dressing."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Asymptomatic cysts require observation. Abscesses require surgical evaluation for drainage under appropriate pediatric anesthesia.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
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      "brands": [],
      "condition_id": "bartholin-cyst-abscess"
    },
    {
      "id": 246,
      "generic": "Amoxicillin + Clavulanic acid",
      "line": 1,
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      "form": "oral.solid",
      "strength_mg": 1000.0,
      "adult_dose": "1 g (875/125 mg) orally twice daily (or 625 mg TID) for 7 days following drainage or for expanding cellulitis",
      "adult_duration": "7 days",
      "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023",
      "rationale": "Broad-spectrum penicillin and beta-lactamase inhibitor combination covering the mixed aerobic and anaerobic flora typically responsible for a Bartholin abscess; an adjunct to drainage, not a substitute for it, since surgical drainage remains the definitive treatment.",
      "cautions": [
        "First-line empirical antibiotic covering polymicrobial vulvar flora (E. coli, Staph aureus, Streptococci, and anaerobes) following incision and drainage or Word catheter placement.",
        "Definitive treatment for a Bartholin abscess is surgical drainage (incision & drainage, Word catheter insertion, or marsupialization); antibiotics alone are insufficient for organized abscesses.",
        "Contraindicated in severe penicillin allergy; caution in hepatic impairment."
      ],
      "peds_mgkg_low": 25.0,
      "peds_mgkg_high": 45.0,
      "peds_max_mg": 1750.0,
      "peds_basis": "day",
      "peds_unit": "mg",
      "peds_note": "25-45 mg/kg/day (amoxicillin component) in 2 divided doses for 7 days.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": [
        {
          "weight_kg": 10,
          "low_mg": 250,
          "high_mg": 450,
          "capped": false
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          "weight_kg": 20,
          "low_mg": 500,
          "high_mg": 900,
          "capped": false
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          "weight_kg": 30,
          "low_mg": 750,
          "high_mg": 1350,
          "capped": false
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          "low_mg": 1000,
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          "capped": true
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          "manufacturer": "JULPHAR",
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          "trade_name": "DEXICLAVE 1 GM 10 F.C. TABS.",
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          "trade_name": "CLAVOCILLIN 1 GM 10 DISPERSIBLE TABS.",
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        {
          "trade_name": "AUGMENTIN ADULTS 1GM/125MG 12 PWD. ORAL SUSP. SACHETS",
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          "manufacturer": "GLAXO SMITHKLINE",
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          "exact_strength": true,
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        },
        {
          "trade_name": "LARYNCLAVE 125/31 PD. FOR ORAL SUSP. 70ML",
          "scientific_name": null,
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          "manufacturer": "MISR > AL ROWAD PHARMACEUTICAL INDUSTRIAL CO.",
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        },
        {
          "trade_name": "MEGACLAVOX 156MG/5ML PD. FOR SUSP. 60 ML",
          "scientific_name": null,
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          "manufacturer": "CID",
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      ],
      "condition_id": "bartholin-cyst-abscess"
    },
    {
      "id": 249,
      "generic": "Referral & safety-netting (no drug therapy)",
      "line": 1,
      "is_adjunct": false,
      "form": null,
      "strength_mg": null,
      "adult_dose": null,
      "adult_duration": null,
      "dose_source": "Bartholin Gland Cyst - disease-level clinical article (bartholin-cyst-abscess-clinical.txt)",
      "rationale": "Carries the referral criteria and warning signs for this condition, which apply whichever treatment is chosen.",
      "cautions": [
        "RED FLAG - Biopsy to rule out malignancy is needed in patients older than 40 or with atypical presentation."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": null,
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      "brands": [],
      "condition_id": "bartholin-cyst-abscess"
    },
    {
      "id": 248,
      "generic": "Cefadroxil",
      "line": 2,
      "is_adjunct": false,
      "form": "oral.solid",
      "strength_mg": 500.0,
      "adult_dose": "1 g daily, as a single dose or in 2 divided doses, for 7 days (combine with Metronidazole if anaerobic involvement suspected)",
      "adult_duration": "7 days",
      "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023",
      "rationale": "First-generation oral cephalosporin used as an alternative antibiotic for Bartholin abscess in patients with mild, non-anaphylactic penicillin allergy; combined with metronidazole when anaerobic involvement is suspected.",
      "cautions": [
        "1 g a day is the whole skin dose. 500 mg twice daily reaches it; 1 g twice daily is double it and is the urinary-tract figure, not the skin one.",
        "Alternative oral cephalosporin for patients with mild non-anaphylactic penicillin allergy.",
        "Use with caution in renal impairment; dosage adjustment may be required."
      ],
      "peds_mgkg_low": 30.0,
      "peds_mgkg_high": 30.0,
      "peds_max_mg": 1000.0,
      "peds_basis": "day",
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      "peds_note": "30 mg/kg/day in 2 divided doses for 7 days.",
      "peds_min_weight_kg": null,
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      "peds_age_min_months": null,
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      "peds_doses": [
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          "weight_kg": 10,
          "low_mg": 300,
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          "capped": false
        },
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          "weight_kg": 20,
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          "high_mg": 600,
          "capped": false
        },
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          "weight_kg": 30,
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          "capped": false
        },
        {
          "weight_kg": 40,
          "low_mg": 1000,
          "high_mg": 1000,
          "capped": true
        }
      ],
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          "trade_name": "MEGADROXIL 500 MG 8 CAPS.",
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          "trade_name": "CURISAFE 500MG 8 CAPS.",
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          "trade_name": "DURICEF 500MG 12 CAPS.",
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        {
          "trade_name": "LONGICEF 125MG/5ML SUSP. 60 ML",
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        },
        {
          "trade_name": "CEFADROXIL 250MG/5ML PD. FOR ORAL SUSP. 60ML",
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      ],
      "condition_id": "bartholin-cyst-abscess"
    },
    {
      "id": 247,
      "generic": "Metronidazole",
      "line": 1,
      "is_adjunct": true,
      "form": "oral.solid",
      "strength_mg": 500.0,
      "adult_dose": "500 mg orally twice to three times daily for 7 days in combination with a second-line aerobic agent (e.g., Cefadroxil)",
      "adult_duration": "7 days",
      "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023",
      "rationale": "Anti-anaerobic agent added alongside an aerobic-spectrum antibiotic such as cefadroxil to cover the anaerobic component of a Bartholin abscess; not used alone, since it leaves the aerobic organisms also implicated in these infections uncovered.",
      "cautions": [
        "Provides targeted coverage for anaerobic pathogens involved in Bartholin abscesses.",
        "Send wound swab for culture and sensitivity, including tests for Neisseria gonorrhoeae and Chlamydia trachomatis.",
        "Strictly avoid alcohol and propylene glycol-containing products during treatment and for 3 days (72 hours) after the last dose - Egyptian National Drug Formulary, Antimicrobial 2023."
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}