# Cardiovascular neoplasm of uncertain behaviour

- Category: chronic
- Review status: reviewed (every claim checked against a document named on this page)
- Sources: ICPC-3 (WONCA International Classification of Primary Care, 3rd edition) class KD25.02 - condition scope only, no dose · No dose - referral pathway, no medicine given in primary care · StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK430685/
- Verified date: 2026-08

## Verified against

- No dose - referral pathway, no medicine given in primary care

## Treatment metadata

- No drug therapy in primary care (Referral & Advice)

## Complete treatment card

```text
CARDIOVASCULAR NEOPLASM OF UNCERTAIN BEHAVIOUR
Sources: ICPC-3 (WONCA International Classification of Primary Care, 3rd edition) class KD25.02 -
         condition scope only, no dose · No dose - referral pathway, no medicine given in primary
         care · StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK430685/
Review status: REVIEWED against the source listed above  (2026-08)

IS IT THIS? - reference only, to read alongside your own examination
  SYMPTOMS - what the patient reports (4)
    - Symptoms tend to be vague and creeping, which delays both diagnosis and surgery
    - Presentations include valve failure, pericardial effusion with tamponade, blocked flow inside
      the heart, arrhythmia and heart failure  [arrhythmia]
    - A growing share cause nothing at all and turn up by chance
    - What shows up depends on tumour size, where it sits, how fast it grows and how far it invades
  TESTS (12)
    - Short of removal, most cardiac masses cannot be pinned down with certainty
    - Bedside echocardiogram is the key first test, with sensitivity and specificity reaching 90%
    - A transoesophageal study adds detail on character and site, and picks up small masses the
      transthoracic view leaves unclear
    - Contrast echo separates a tumour from a clot in the heart
    - Cardiac MRI gauges size, site, mobility and the effect on neighbouring structures
    - MRI alone characterises the tissue, tells cystic or waterlogged tissue apart, and gauges blood
      supply on first-pass perfusion
    - Late gadolinium picks up extracellular matrix; no uptake points instead to a clot
    - Telling benign from malignant, cardiac MRI reached up to 79% accuracy in small groups of
      patients
    - Fat suppression sequences pick out fatty tumours such as lipoma and liposarcoma
    - CT reads the mass and its neighbours, judging nature from x-ray attenuation, and shows calcium
    - Left heart catheterisation maps blood supply, invasion of epicardial vessels and spread into
      the ventricle
    - Removing the tumour and examining it under the microscope is what settles the type
  IF NOT THIS - what else fits (4)
    - A mass in the heart may instead be a clot or a vegetation
    - With an implanted device or prosthesis plus infection, vegetation moves up the list
    - In a cancer patient, heart failure may be chemotherapy toxicity rather than spread of the
      tumour
    - Infection itself can throw up masses or fluid around the heart, so send microbiology
  Source  StatPearls "Cardiac Tumors" - disease-level clinical article
  Status  traced to the source above

1. NO DRUG THERAPY IN PRIMARY CARE (REFERRAL & ADVICE)    [1st line]
   Adult    A pathology-style category for a cardiovascular growth whose behaviour has not yet been
            determined; the GP's role is simply to refer for the biopsy or imaging that will
            classify it, not to treat. This code is more likely used for registry/coding purposes
            than as something a GP diagnoses directly. - Refer, with advice
   Peds     Children follow the same pathway: recognise and refer. No primary-care medicine is
            implied.
   Source   No dose - referral pathway, no medicine given in primary care
   Why      A pathology-style category for a cardiovascular growth whose behaviour has not yet been
            determined; the GP's role is simply to refer for the biopsy or imaging that will
            classify it, not to treat. This code is more likely used for registry/coding purposes
            than as something a GP diagnoses directly.
   Caution  RED FLAG - Pericardial effusion with tamponade: assess urgently and refer.
            RED FLAG - Hemodynamic compromise / cardiac inflow-outflow obstruction: assess urgently
            and refer.
            RED FLAG - Embolic events (stroke, systemic embolization): assess urgently and refer.
            None specific beyond ensuring the diagnostic work-up is not delayed.
            Rare in Egyptian primary care.
            No medicine is prescribed for this in primary care - this entry is for recognition and
            referral. Anything given is decided by the service it is referred to.

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.
```

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