Dawaa Reference

chronic

Cervical dysplasia / carcinoma in situ (abnormal Pap smear)

Treatment options, dosing, cautions and Egyptian brands from the shipped Dawaa Reference card.

Evidence status

Checked against the sources named below

Sources3 sources

Cervical Intraepithelial Neoplasia - StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK544371/ · ICPC-3 (WONCA International Classification of Primary Care, 3rd edition) class GD32 - condition scope only, no dose · No dose - referral pathway, no medicine given in primary care

Verified against1 document
  • No dose - referral pathway, no medicine given in primary care

Verified date2026-08

Presentation reference

Is it this?

Reference only, to read alongside your own examination.

Tests (8)

  • Screening Pap smear, usually liquid-based cytology, checks cell appearance for abnormality
  • High-risk HPV subtype testing can be run from the same liquid sample when indicated
  • On colposcopy, 5% acetic acid is applied and dysplastic tissue turns aceto-white
  • Lugol iodine solution can be used when acetic acid fails to show abnormalities, leaving a non-staining patch
  • Biopsy of any abnormal-looking area lets pathology confirm dysplasia
  • The smear samples the squamocolumnar junction, where columnar lining is being replaced by squamous, and that is where the trouble starts
  • That changing area is where HPV gets in, and HPV is behind more than 90% of cervical cancer
  • The smear is the reason cervical cancer became both less common and less often fatal

If not this — what else fits (4)

  • Cervicitis is a differential to exclude
  • Endometrial carcinoma is a differential to exclude
  • Pelvic inflammatory disease is a differential to exclude
  • Vaginitis is a differential to exclude

SourceStatPearls "Cervical Dysplasia" - disease-level clinical article

Presentation findings are traced to the source above.

1

NO DRUG THERAPY IN PRIMARY CARE (REFERRAL & ADVICE)

1st line
Adult dose and duration

Cervical dysplasia or carcinoma-in-situ, usually picked up on an abnormal Pap smear; the GP orders or reviews the smear and refers for colposcopy rather than treating it directly. - Refer, with advice

Paediatric dose

Children follow the same pathway: recognise and refer. No primary-care medicine is implied.

Dose source

No dose - referral pathway, no medicine given in primary care

Why

Cervical dysplasia or carcinoma-in-situ, usually picked up on an abnormal Pap smear; the GP orders or reviews the smear and refers for colposcopy rather than treating it directly.

Cautions
  • No medicine is prescribed for this in primary care - this entry is for recognition and referral. Anything given is decided by the service it is referred to.
  • RED FLAG - Postcoital or intermenstrual bleeding, a high-grade abnormality on cytology, or a visible cervical lesion on speculum examination: refer urgently.

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.