{
  "schema_version": 1,
  "kind": "condition",
  "id": "chagas-disease",
  "name": "Chagas Disease (American Trypanosomiasis)",
  "category": "chronic",
  "sources": "Chagas Disease - StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK459272/ · ICPC-3 (WONCA International Classification of Primary Care, 3rd edition) class AD24.01 - condition scope only, no dose · No dose - referral pathway, no medicine given in primary care",
  "review_status": "reviewed",
  "verified_against": "No dose - referral pathway, no medicine given in primary care",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 388,
      "generic": "No drug therapy in primary care (Recognition & Referral)",
      "line": 1,
      "is_adjunct": false,
      "form": null,
      "strength_mg": null,
      "adult_dose": "Chronic protozoal infection spread by triatomine ('kissing') bugs found only in the Americas. Not a Cairo diagnosis except in someone who lived in or travelled extensively through Latin America; the specific drugs (benznidazole, nifurtimox) are not marketed in Egypt, so any suspected case needs referral to a tropical medicine centre.",
      "adult_duration": "Refer",
      "dose_source": "No dose - referral pathway, no medicine given in primary care",
      "rationale": "Chronic protozoal infection spread by triatomine ('kissing') bugs found only in the Americas. Not a Cairo diagnosis except in someone who lived in or travelled extensively through Latin America; the specific drugs (benznidazole, nifurtimox) are not marketed in Egypt, so any suspected case needs referral to a tropical medicine centre.",
      "cautions": [
        "Not endemic in Egypt. Relevant to a returning traveller or an imported case; consider the travel history before anything else.",
        "No medicine is prescribed for this in primary care - this entry is for recognition and referral. Anything given is decided by the service it is referred to.",
        "RED FLAG - An acute febrile illness with periorbital swelling (Romana's sign) after a relevant exposure, or unexplained cardiomyopathy, megacolon or megaoesophagus in a patient with a relevant Latin American residence history: refer for specialist assessment."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Children follow the same pathway: recognise and refer. No primary-care medicine is implied.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [],
      "condition_id": "chagas-disease"
    }
  ]
}