{ "schema_version": 1, "kind": "condition", "id": "community-acquired-pneumonia", "name": "Community-acquired pneumonia", "category": "infectious", "sources": "ATS/IDSA CAP Guideline 2019 · Egyptian National Drug Formulary - Antimicrobial 2023 (doxycycline monograph) · MSF Essential Drugs 2024 - paracetamol (oral)", "review_status": "reviewed", "verified_against": "ATS/IDSA CAP Guideline 2019 · Egyptian National Drug Formulary - Antimicrobial 2023 (doxycycline monograph) · MSF Essential Drugs 2024 - paracetamol (oral) · Community-Acquired Pneumonia - disease-level clinical article (community-acquired-pneumonia-clinical.txt)", "verified_date": "2026-08", "treatments": [ { "id": 457, "generic": "Amoxicillin", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 500.0, "adult_dose": "500-1000 mg TID", "adult_duration": "5-7 days", "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023", "rationale": "Narrower-spectrum beta-lactam used first-line for mild community-acquired pneumonia without comorbidities, targeting the typical bacterial pathogens responsible for most uncomplicated cases.", "cautions": [ "Switch to broad spectrum if no improvement in 48-72h.", "Amoxicillin is first-line for mild CAP without comorbidities.", "Penicillin hypersensitivity is a contraindication." ], "peds_mgkg_low": 80.0, "peds_mgkg_high": 90.0, "peds_max_mg": 1000.0, "peds_basis": "day", "peds_unit": "mg", "peds_note": "Divided BID-TID; targets penicillin-intermediate S. pneumoniae ENDF caps amoxicillin at 500 mg per dose for most indications; at the twice-daily schedule this regimen uses, that is 1,000 mg in a day, which is the ceiling applied to the table above (ENDF Antimicrobial 2023).", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 800, "high_mg": 900, "capped": false }, { "weight_kg": 20, "low_mg": 1000, "high_mg": 1000, "capped": true }, { "weight_kg": 30, "low_mg": 1000, "high_mg": 1000, "capped": true }, { "weight_kg": 40, "low_mg": 1000, "high_mg": 1000, "capped": true } ], "brands": [ { "trade_name": "AMOXYCILLIN 500MG 10 CAPS B.P.2013", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 6.5, "pack_count": 10, "unit_price": 0.65, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "AMOXICILLIN 500MG 12 CAPS. USP 28", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "OCTOBER PHARMA", "price_egp": 8.1, "pack_count": 12, "unit_price": 0.67, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "AMOXIL 500MG 12 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP > SMITHKLINE BEECHAM", "price_egp": 9.0, "pack_count": 12, "unit_price": 0.75, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "AMOXICID 500 MG 12 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CID", "price_egp": 9.5, "pack_count": 12, "unit_price": 0.79, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "E-MOX 500 MG 16 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 15.6, "pack_count": 16, "unit_price": 0.97, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "HICONCIL 500MG 12 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 11.6, "pack_count": 12, "unit_price": 0.97, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BIOMOX 500MG 12 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SEDICO", "price_egp": 19.5, "pack_count": 12, "unit_price": 1.62, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "IBIAMOX 500 MG 12 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AMOUN", "price_egp": 45.0, "pack_count": 12, "unit_price": 3.75, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "HICILLIN 125MG/5ML SUSP. 80ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL NASR", "price_egp": 3.0, "pack_count": null, "unit_price": null, "strength_mg": 125.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "AMOXIL FORT 250MG/5ML SUSP. 60ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP > SMITHKLINE BEECHAM", "price_egp": 5.5, "pack_count": null, "unit_price": null, "strength_mg": 250.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "community-acquired-pneumonia" }, { "id": 458, "generic": "Amoxicillin + Clavulanic acid", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 1000.0, "adult_dose": "1 g BID or 875/125 mg BID", "adult_duration": "7 days", "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023", "rationale": "Beta-lactam combined with a beta-lactamase inhibitor, used as first-line empirical outpatient therapy for community-acquired pneumonia; the inhibitor restores activity against beta-lactamase-producing organisms that amoxicillin alone would miss.", "cautions": [ "Take with food to minimize GI adverse effects.", "This combination is first-line outpatient empirical therapy in Egypt.", "There is a risk of cholestatic jaundice with prolonged use." ], "peds_mgkg_low": 80.0, "peds_mgkg_high": 90.0, "peds_max_mg": 3000.0, "peds_basis": "day", "peds_unit": "mg", "peds_note": "Of the amoxicillin component, divided BID (use 14:1 ES-600 formulation to keep clavulanate <10 mg/kg/day)", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 800, "high_mg": 900, "capped": false }, { "weight_kg": 20, "low_mg": 1600, "high_mg": 1800, "capped": false }, { "weight_kg": 30, "low_mg": 2400, "high_mg": 2700, "capped": false }, { "weight_kg": 40, "low_mg": 3000, "high_mg": 3000, "capped": true } ], "brands": [ { "trade_name": "E-MOXCLAV 1G 10 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 14.0, "pack_count": 10, "unit_price": 1.4, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "JULMENTIN 2X 1GM 15 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JULPHAR", "price_egp": 57.5, "pack_count": 15, "unit_price": 3.83, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DEXICLAVE 1 GM 10 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA > NOVELL PHARMA", "price_egp": 38.5, "pack_count": 10, "unit_price": 3.85, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MACLAVEX 1 GM 14 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MASH PREMIERE", "price_egp": 105.0, "pack_count": 14, "unit_price": 7.5, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CLAVIMOX 1 GM 12 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 130.0, "pack_count": 12, "unit_price": 10.83, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MEGAMOX 1 GM 14 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AL JAZEERA PHARMACEUTICAL > HIKMA PHARMA", "price_egp": 178.0, "pack_count": 14, "unit_price": 12.71, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CLAVOCILLIN 1 GM 10 DISPERSIBLE TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA > ORGANOPHARMA", "price_egp": 106.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "AUGMENTIN ADULTS 1GM/125MG 12 PWD. ORAL SUSP. SACHETS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 169.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LARYNCLAVE 125/31 PD. FOR ORAL SUSP. 70ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MISR > AL ROWAD PHARMACEUTICAL INDUSTRIAL CO.", "price_egp": 8.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "MEGACLAVOX 156MG/5ML PD. FOR SUSP. 60 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CID", "price_egp": 8.0, "pack_count": null, "unit_price": null, "strength_mg": 156.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "community-acquired-pneumonia" }, { "id": 463, "generic": "Referral & safety-netting (no drug therapy)", "line": 1, "is_adjunct": false, "form": null, "strength_mg": null, "adult_dose": null, "adult_duration": null, "dose_source": "Community-Acquired Pneumonia - disease-level clinical article (community-acquired-pneumonia-clinical.txt)", "rationale": "Carries the referral criteria and warning signs for this condition, which apply whichever treatment is chosen.", "cautions": [ "RED FLAG - The inpatient admission criterion is a CURB-65 score >= 2." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": null, "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [], "condition_id": "community-acquired-pneumonia" }, { "id": 459, "generic": "Clarithromycin", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": 500.0, "adult_dose": "500 mg BID", "adult_duration": "7 days", "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023", "rationale": "Not used alone here. The 2019 ATS/IDSA guidance prefers high-dose amoxicillin as empiric therapy for healthy outpatients 64 and under, and allows a macrolide alone only where local S. pneumoniae macrolide resistance stays under 25%. The same guidance reports resistance often above 30% in the US and above 25% across most of the rest of the world, and no Egyptian figure appears in the cited sources, so that 25% condition cannot be shown to hold here. The Egyptian formulary uses the same cutoff and also defaults to combination therapy. Combine with a beta-lactam, or use levofloxacin instead.", "cautions": [ "Covers atypical pathogens (Mycoplasma, Chlamydia pneumoniae).", "Use in penicillin allergy or as add-on in moderate CAP.", "There is a risk of QT prolongation." ], "peds_mgkg_low": 15.0, "peds_mgkg_high": 15.0, "peds_max_mg": 1000.0, "peds_basis": "day", "peds_unit": "mg", "peds_note": "Divided BID for 7 days", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 150, "high_mg": 150, "capped": false }, { "weight_kg": 20, "low_mg": 300, "high_mg": 300, "capped": false }, { "weight_kg": 30, "low_mg": 450, "high_mg": 450, "capped": false }, { "weight_kg": 40, "low_mg": 600, "high_mg": 600, "capped": false } ], "brands": [ { "trade_name": "KAPIFECTIN 500 MG 14 F.C.TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EVA PHARMA", "price_egp": 37.0, "pack_count": 14, "unit_price": 2.64, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LARITHROCIN 500MG 14 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS", "price_egp": 40.0, "pack_count": 14, "unit_price": 2.86, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CAPRIVEXIN 500MG S.R. 14 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "HORUS FOR PHARMACEUTICAL PRODUCTS", "price_egp": 58.0, "pack_count": 14, "unit_price": 4.14, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CLARINOTION XL 500 MG 14 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA > NOTION PHARMA", "price_egp": 83.0, "pack_count": 14, "unit_price": 5.93, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "KLARIMIX 500 MG 14 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA > OCTOBER PHARMA", "price_egp": 144.0, "pack_count": 14, "unit_price": 10.29, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "INFECTOCURE 500 MG 14 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EGPI", "price_egp": 156.0, "pack_count": 14, "unit_price": 11.14, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "KLACID 500 MG 14 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA > ABBOTT LABORATORIES", "price_egp": 257.0, "pack_count": 14, "unit_price": 18.36, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "KLACID XL 500 MG 14 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA > ABBOTT LABORATORIES", "price_egp": 299.0, "pack_count": 14, "unit_price": 21.36, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "KLARIMIX 125MG/5ML SUSP. 60ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA", "price_egp": 36.0, "pack_count": null, "unit_price": null, "strength_mg": 125.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "KLARIMIX 250MG/5ML SUSP. 60ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA", "price_egp": 52.0, "pack_count": null, "unit_price": null, "strength_mg": 250.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "community-acquired-pneumonia" }, { "id": 460, "generic": "Levofloxacin", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": 500.0, "adult_dose": "750 mg once daily", "adult_duration": "5-7 days", "dose_source": "ATS/IDSA CAP Guideline 2019", "rationale": "Respiratory fluoroquinolone with broad activity against both typical and atypical pneumonia pathogens; reserved for patients with comorbidities or those failing first-line beta-lactam therapy, rather than used as initial treatment.", "cautions": [ "Reserve for comorbidities or failure of first-line agents.", "Levofloxacin can cause QT prolongation and glycemic dysregulation.", "There is a risk of tendinitis, tendon rupture, and aortic aneurysm." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Contraindicated in children under 18 years (arthropathy risk)", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "FLOXABACT 500 MG 10 F.C.TABS.(NOW LEVOFLOXACIN-EVA)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EVA PHARMA", "price_egp": 40.0, "pack_count": 10, "unit_price": 4.0, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LEVOMAGICTAM 500 MG 5 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEDIZEN PHARMACEUTICAL INDUSTRIES > MAGIC PHARMA-EGYPT", "price_egp": 27.0, "pack_count": 5, "unit_price": 5.4, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "EXACINOP 500 MG 10 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL-OBOUR > MASSA GROUP PHARMA", "price_egp": 65.0, "pack_count": 10, "unit_price": 6.5, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ROYAFLOXACIN 500 MG 10 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEDIZEN PHARMACEUTICAL INDUSTRIES > SATO PHARMA", "price_egp": 92.0, "pack_count": 10, "unit_price": 9.2, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TAVIXINOR 500 MG 5 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MASH PREMIERE > SAS PHARMA", "price_egp": 64.5, "pack_count": 5, "unit_price": 12.9, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BIOWORLD 500 MG 10 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EGPI > BIOWORLD", "price_egp": 133.0, "pack_count": 10, "unit_price": 13.3, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TAVANIC 500 MG 5 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI", "price_egp": 192.0, "pack_count": 5, "unit_price": 38.4, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ALFASPECT 500 MG 5 S.F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SPIMACO PHARMACEUTICAL INDUSTRIES > INNOGEN PHARMA", "price_egp": 70.0, "pack_count": null, "unit_price": null, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "community-acquired-pneumonia" }, { "id": 461, "generic": "Doxycycline", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": 100.0, "adult_dose": "100 mg twice daily", "adult_duration": "5-7 days", "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023 (doxycycline monograph)", "rationale": "The Egyptian EML 2025 lists doxycycline as second choice for mild-to-moderate community acquired pneumonia, and it sits in the Access group where clarithromycin and levofloxacin sit in Watch. It covers Mycoplasma, so it is the atypical cover to reach for where a macrolide is unsuitable.", "cautions": [ "Access group - it does not carry the stewardship cost of clarithromycin or levofloxacin, both of which are Watch.", "Avoid in pregnancy from the second trimester, and in breastfeeding beyond short courses.", "Swallow with a full glass of water and stay sitting up for 30 minutes - it ulcerates the oesophagus if it lodges.", "Antacids, iron and calcium block absorption; separate them.", "Photosensitivity - relevant year-round in Egypt." ], "peds_mgkg_low": 2.2, "peds_mgkg_high": 2.2, "peds_max_mg": 100.0, "peds_basis": "dose", "peds_unit": "mg", "peds_note": "2.2 mg/kg per dose every 12 hours, maximum 100 mg per dose. The formulary restricts use under 8 years to severe or life-threatening infection, or where there is no better alternative - in practice that means a child with CAP gets amoxicillin, not this.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 22, "high_mg": 22, "capped": false }, { "weight_kg": 20, "low_mg": 44, "high_mg": 44, "capped": false }, { "weight_kg": 30, "low_mg": 66, "high_mg": 66, "capped": false }, { "weight_kg": 40, "low_mg": 88, "high_mg": 88, "capped": false } ], "brands": [ { "trade_name": "FARCODOXIN 100MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 11.0, "pack_count": 10, "unit_price": 1.1, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DOXY M.R.100 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ADWIA", "price_egp": 12.0, "pack_count": 10, "unit_price": 1.2, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "GRANUDOXY 100MG 10 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS > PIERRE FRANCE", "price_egp": 12.0, "pack_count": 10, "unit_price": 1.2, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DOXYDOX 100 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 23.0, "pack_count": 10, "unit_price": 2.3, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DOXYMYCIN 100 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL NILE.", "price_egp": 30.0, "pack_count": 10, "unit_price": 3.0, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TABOCINE 100MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "TABUK PHARMACEUTICAL MANUFACTURING COMPANY > TABUK PHARMA", "price_egp": 46.0, "pack_count": 10, "unit_price": 4.6, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VIBRAMYCIN 100MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PFIZER", "price_egp": 65.0, "pack_count": 10, "unit_price": 6.5, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "community-acquired-pneumonia" }, { "id": 462, "generic": "Paracetamol", "line": 1, "is_adjunct": true, "form": "oral.solid", "strength_mg": 500.0, "adult_dose": "1 g three or four times daily, maximum 4 g in 24 hours", "adult_duration": "while febrile or the chest hurts, usually 3-5 days", "dose_source": "MSF Essential Drugs 2024 - paracetamol (oral)", "rationale": "The WHO pocket book instructs paracetamol for a child with pneumonia and a distressing fever of 39 C or more, and gives 15 mg/kg every 6 hours. The adult dose here is from the MSF drug reference. Paracetamol rather than an NSAID is deliberate - see the cautions.", "cautions": [ "WHO treats fever only when it is 39 C or above and distressing the child - a moderate fever in pneumonia does not need suppressing.", "Paracetamol, not an NSAID, is the antipyretic of choice here: NSAID use in community-acquired pneumonia is associated with delayed diagnosis and with pleuropulmonary complications.", "Check every other product for paracetamol content before adding it.", "Reduce the maximum in liver disease or in an adult under 50 kg.", "500 mg is the per-dose ceiling used here for a child. 1000 mg is the adult dose and does not belong in a weight calculation - the daily 60 mg/kg limit is the one that binds first in any case." ], "peds_mgkg_low": 15.0, "peds_mgkg_high": 15.0, "peds_max_mg": 500.0, "peds_basis": "dose", "peds_unit": "mg", "peds_note": "15 mg/kg per dose every 6 hours. WHO restricts oral paracetamol to children 2 months and over with a fever of 39 C or more who are uncomfortable or distressed by it - do not treat a low fever.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 150, "high_mg": 150, "capped": false }, { "weight_kg": 20, "low_mg": 300, "high_mg": 300, "capped": false }, { "weight_kg": 30, "low_mg": 450, "high_mg": 450, "capped": false }, { "weight_kg": 40, "low_mg": 500, "high_mg": 500, "capped": true } ], "brands": [ { "trade_name": "FEBRIMOL 500 MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 3.5, "pack_count": 20, "unit_price": 0.17, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CETAMOL 500 MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 8.0, "pack_count": 20, "unit_price": 0.4, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PARACETAMOL-MUP 500MG B.P. 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP", "price_egp": 13.0, "pack_count": 20, "unit_price": 0.65, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CETAL 500 MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 24.0, "pack_count": 20, "unit_price": 1.2, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ARKADOLOW 500 MG 30 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UTOPIA", "price_egp": 42.0, "pack_count": 30, "unit_price": 1.4, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PARAMOL 500MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MISR", "price_egp": 38.0, "pack_count": 20, "unit_price": 1.9, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ADOL 500MG 24 CAPLETS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JULPHAR", "price_egp": 32.0, "pack_count": null, "unit_price": null, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "AUGICETAMIDE 500 MG 20 SACHETS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AUG PHARMA", "price_egp": 50.0, "pack_count": null, "unit_price": null, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FEBRIMOL ORAL DROPS 20 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 4.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "THERA-LO 3.2G/100ML ORAL SUSP. 100 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 5.0, "pack_count": null, "unit_price": null, "strength_mg": 3200.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "community-acquired-pneumonia" } ] }