{ "schema_version": 1, "kind": "condition", "id": "contact-dermatitis", "name": "Contact dermatitis (irritant or allergic)", "category": "chronic", "sources": "NICE CKS Contact Dermatitis 2021 · Egyptian National Drug Formulary - Endocrine System 2024 (betamethasone monograph) · Hydrocortisone 1% cream SmPC section 4.2 (eMC product 13103) · Contact Dermatitis - disease-level clinical article (contact-dermatitis-clinical.txt) · Egyptian National Drug Formulary - Respiratory System 2026 (cetirizine monograph) · Egyptian National Drug Formulary - Endocrine System 2024 (prednisolone monograph)", "review_status": "reviewed", "verified_against": "Egyptian National Drug Formulary - Endocrine System 2024 (betamethasone monograph) · Hydrocortisone 1% cream SmPC section 4.2 (eMC product 13103) · Contact Dermatitis - disease-level clinical article (contact-dermatitis-clinical.txt) · Egyptian National Drug Formulary - Respiratory System 2026 (cetirizine monograph) · Egyptian National Drug Formulary - Endocrine System 2024 (prednisolone monograph)", "verified_date": "2026-08", "treatments": [ { "id": 485, "generic": "Betamethasone", "line": 1, "is_adjunct": false, "form": "topical", "strength_mg": null, "adult_dose": "Apply 0.1% cream/ointment thinly once or twice daily", "adult_duration": null, "dose_source": "Egyptian National Drug Formulary - Endocrine System 2024 (betamethasone monograph)", "rationale": "Potent topical corticosteroid that suppresses the local inflammatory response driving contact dermatitis; used first-line on thicker skin away from the face and flexures, where a more potent steroid is needed to control inflammation.", "cautions": [ "Identify and eliminate triggering contact allergen/irritant.", "Apply emollients frequently as maintenance therapy.", "The Egyptian formulary limits a course to 5 days when this is used on the face or in a child - 0.1% betamethasone is potent and the face thins fastest.", "Rosacea, acne, perioral dermatitis, perianal and genital pruritus." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Child >1 year: use hydrocortisone 1% cream for short courses", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "CRONOMESONE 0.1% CREAM 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 4.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CRONOMESONE 0.1% OINT. 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 4.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BETNOVATE 0.1% TOP. OINT. 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SMITHKLINE BEECHAM > GLAXO SMITHKLINE", "price_egp": 6.9, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BETADERM 0.1% CREAM 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 18.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BETAVAL 0.1% CREAM 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 20.0, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BETADERM 0.1% CREAM 30 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 23.0, "pack_count": null, "unit_price": null, "strength_mg": 30000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BETAMETHASONE DIPROPIONATE 0.05% CREAM 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AMRIYA", "price_egp": 11.5, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BETAMETHASONE DIPROPIONATE 0.05% OINT. 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AMRIYA", "price_egp": 11.5, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "contact-dermatitis" }, { "id": 487, "generic": "Referral & safety-netting (no drug therapy)", "line": 1, "is_adjunct": false, "form": null, "strength_mg": null, "adult_dose": null, "adult_duration": null, "dose_source": "Contact Dermatitis - disease-level clinical article (contact-dermatitis-clinical.txt)", "rationale": "Carries the referral criteria and warning signs for this condition, which apply whichever treatment is chosen.", "cautions": [ "RED FLAG - Contact urticaria (a form of contact dermatitis) can progress to anaphylaxis." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": null, "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [], "condition_id": "contact-dermatitis" }, { "id": 486, "generic": "Hydrocortisone", "line": 2, "is_adjunct": false, "form": "topical", "strength_mg": null, "adult_dose": "To be applied sparingly to the affected skin two or three times daily after gently cleansing the area.", "adult_duration": null, "dose_source": "Hydrocortisone 1% cream SmPC section 4.2 (eMC product 13103)", "rationale": "Mild-potency topical corticosteroid preferred for facial, flexural, or other delicate skin where a potent steroid like betamethasone is contraindicated; it still works by suppressing local inflammation but with lower risk of skin thinning in these sensitive areas.", "cautions": [ "Hydrocortisone is the preferred initial choice for facial, flexural, or delicate skin areas where potent steroids are contraindicated.", "Hydrocortisone is a mild potency steroid, safe for facial or pediatric contact dermatitis.", "Discontinue when inflammation resolves.", "Avoid continuous application for >2 weeks.", "Limit a course in a child to 7-10 days, and remember the face and scalp absorb far more than limb skin.", "Hydrocortisone Cream is contra-indicated in patients with bacterial, viral or fungal infections of the skin. Urticaria, rosacea, ulcers and local infection are also contra-indications." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Adults and children: To be applied sparingly to the affected skin two or three times daily after gently cleansing the area. Courses of treatment in children should generally be limited to not more than seven to ten days.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "NOVACORTIN 1% CREAM 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 4.75, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NOVACORTIN 1% OINT. 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 4.75, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MICORT 1% CREAM 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MISR", "price_egp": 12.5, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "HYDROCORTISONE 1% OINT. 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MISR", "price_egp": 21.0, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "contact-dermatitis" }, { "id": 489, "generic": "Prednisolone", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": 5.0, "adult_dose": "5 to 60 mg/day as a single daily dose or in 2 to 4 divided doses, tapered", "adult_duration": null, "dose_source": "Egyptian National Drug Formulary - Endocrine System 2024 (prednisolone monograph)", "rationale": "The disease article reserves systemic steroid for severe contact dermatitis and requires a gradual taper to prevent rebound.", "cautions": [ "Abrupt withdrawal is not recommended, particularly with doses of 40 mg or more or 3 weeks of treatment or more.", "The dose should be gradually decreased to the lowest dose that maintains an adequate clinical response.", "The ENDF gives a dose range across all systemic indications, not a contact-dermatitis regimen - the indication comes from the disease article." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "The ENDF prednisolone monograph gives no paediatric figure for this indication, so none is stated here.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "HOSTACORTIN H 5MG 30 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI", "price_egp": 12.0, "pack_count": 30, "unit_price": 0.4, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PREDNISOLONE 5 MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 24.0, "pack_count": 20, "unit_price": 1.2, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PREDILONE 5MG 10 TAB. (25 STRIPS PACK)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 250.0, "pack_count": 10, "unit_price": 25.0, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "EPICOPRED 5 MG 30 ORODISPERSIBLE TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 69.0, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PREDNISOLONE-EVA 5 MG 30 ORODISPERSIBLE TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EVA PHARMA", "price_egp": 79.5, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DISPRELONE-OD 5 MG 30 ORODISPERSABLE TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ANDALOUS PHARMA", "price_egp": 84.0, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SOLUPRED ORO 5 MG 30 ORODISPERSIBLE TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI WINTHROP > SANOFI", "price_egp": 84.0, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ACETASEE 1% EYE DROPS (SUSP.) 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA", "price_egp": 7.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "PREDNIS 5MG/5ML SYRUP 100 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 9.5, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "contact-dermatitis" }, { "id": 488, "generic": "Cetirizine", "line": 2, "is_adjunct": true, "form": "oral.solid", "strength_mg": 10.0, "adult_dose": "10 mg once daily", "adult_duration": "as-needed", "dose_source": "Egyptian National Drug Formulary - Respiratory System 2026 (cetirizine monograph)", "rationale": "The disease article adds an oral antihistamine to control pruritus alongside the topical steroid; the card carried topical treatment only.", "cautions": [ "The ENDF oral indications are allergic rhinitis and chronic idiopathic urticaria - use for contact-dermatitis pruritus rests on the disease article, not on the formulary indication." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "ENDF oral dosing by age band. The formulary's oral indications are allergic rhinitis and chronic idiopathic urticaria; the contact-dermatitis indication comes from the disease article.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": 24.0, "peds_age_max_months": null, "peds_age_bands": [ { "label": "2 to under 6 years", "age_min_months": 24, "age_max_months": 71, "dose_text": "2.5 mg once to twice daily" }, { "label": "6 to under 12 years", "age_min_months": 72, "age_max_months": 143, "dose_text": "5 mg twice daily, or 10 mg once daily based on severity" }, { "label": "12 years and over", "age_min_months": 144, "age_max_months": 216, "dose_text": "10 mg once daily" } ], "peds_doses": null, "brands": [ { "trade_name": "EPIRIZINE 10 MG 10 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 15.5, "pack_count": 10, "unit_price": 1.55, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CETRITIN 10MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL NILE.", "price_egp": 42.0, "pack_count": 20, "unit_price": 2.1, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TOMAZINE 10MG 30 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALFACURE PHARMACEUTICALS", "price_egp": 63.0, "pack_count": 30, "unit_price": 2.1, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CETRAK 10 MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 68.0, "pack_count": 20, "unit_price": 3.4, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "HISTAZINE-1 10 MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AMRIYA", "price_egp": 68.0, "pack_count": 20, "unit_price": 3.4, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ZYRTEC 10 MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 100.0, "pack_count": 20, "unit_price": 5.0, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CETRICHEW 10MG 20 CHEWABLE F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AL ROWAD PHARMACEUTICAL INDUSTRIAL CO.", "price_egp": 15.0, "pack_count": null, "unit_price": null, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "HISTA CHEW 10 MG 20 CHEWABLE TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB CAPS > ADVOCURE", "price_egp": 15.0, "pack_count": null, "unit_price": null, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LERGFREE 5MG/5ML SYRUP 120ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "DEBEIKY", "price_egp": 9.0, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "EPIRIZINE 5MG/ML SYRUP 60 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 19.0, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "contact-dermatitis" } ] }