{ "schema_version": 1, "kind": "condition", "id": "corneal-abrasion", "name": "Simple corneal abrasion", "category": "chronic", "sources": "Egyptian National Drug Formulary - Antimicrobial 2023 · AAO Corneal Abrasion Guidelines · Exocin 3 mg/ml Eye Drops SmPC section 4.2 (eMC product 1353) · No labelled dose - a lubricant appliance, not a licensed medicine; instilled as often as comfort needs · Tobramycin 0.3% eye drops SmPC (https://www.medicines.org.uk/emc/product/3120/smpc) · Corneal Abrasion - StatPearls - NCBI Bookshelf - disease-level clinical article (corneal-abrasion-full.txt) · Domingo E, Moshirfar M, Zeppieri M, et al. Corneal Abrasion. [Updated 2024 Jan 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Bookshelf ID NBK532960.", "review_status": "reviewed", "verified_against": "Egyptian National Drug Formulary - Antimicrobial 2023 · Exocin 3 mg/ml Eye Drops SmPC section 4.2 (eMC product 1353) · No labelled dose - a lubricant appliance, not a licensed medicine; instilled as often as comfort needs · Tobramycin 0.3% eye drops SmPC (https://www.medicines.org.uk/emc/product/3120/smpc) · Corneal Abrasion - StatPearls (NBK532960), Treatment / Management · Corneal Abrasion - StatPearls - NCBI Bookshelf - disease-level clinical article (corneal-abrasion-full.txt) · Domingo E, Moshirfar M, Zeppieri M, et al. Corneal Abrasion. [Updated 2024 Jan 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Bookshelf ID NBK532960.", "verified_date": "2026-08", "treatments": [ { "id": 506, "generic": "Tobramycin", "line": 1, "is_adjunct": false, "form": "eye", "strength_mg": null, "adult_dose": "Instill 1-2 drops into affected eye(s) every 4 hours", "adult_duration": null, "dose_source": "Tobramycin 0.3% eye drops SmPC (https://www.medicines.org.uk/emc/product/3120/smpc)", "rationale": "Prophylactic topical antibiotic to prevent bacterial keratitis while epithelium heals", "cautions": [ "CONTACT LENS WEARERS REQUIRE PSEUDOMONAS COVER (e.g. ofloxacin or levofloxacin) and MUST NOT wear lenses until 24 hours after full epithelial closure.", "NEVER prescribe topical anesthetic drops (tetracaine/benoxinate) for outpatient home use (causes rapid corneal melting and permanent blindness).", "Do NOT patch the eye if contact-lens-related or organic/plant material injury (high infection risk).", "RED FLAG - Topical corticosteroid drops must never be used on a corneal abrasion - they delay healing and increase the risk of infection.", "An irregularly shaped pupil after eye trauma suggests globe rupture and needs immediate ophthalmology involvement.", "RED FLAG - Aminoglycoside eye drops should be avoided in patients who do not wear contact lenses.", "Evert both eyelids before concluding the examination - a retained subtarsal foreign body typically produces vertical linear corneal scratches.", "Branching, dendritic fluorescein staining is herpes keratitis rather than a simple abrasion and needs immediate treatment.", "RED FLAG - Do not patch an uncomplicated minor traumatic or foreign-body corneal abrasion.", "Inspect the anterior chamber for blood in it (hyphema) at the first examination.", "Any significant reduction in visual acuity requires referral to an ophthalmologist.", "RED FLAG - Purulent discharge, or a drop in vision of more than one to two Snellen lines, is an indication for urgent ophthalmology referral.", "RED FLAG - A child who is still unwilling to open the injured eye 24 hours later needs urgent ophthalmology referral." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Children >2 months: Instill 1-2 drops into affected eye(s) every 4 hours", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "3 months and over", "age_min_months": 3, "age_max_months": 216, "dose_text": "1 to 2 drops into affected eye every 4 hours." } ], "peds_doses": null, "brands": [ { "trade_name": "SWIXTOBRAM 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CHEMIPHARM", "price_egp": 6.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "T GRAND 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "DELTA GRAND PHARMA", "price_egp": 7.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TOBRAL 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 7.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TOBRACTIVA 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EPCI", "price_egp": 18.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "AVAZIR 0.3% EYE DROPS 10 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ORCHIDIA PHARMACEUTICAL INDUSTRIES > ORCHIDIA", "price_egp": 28.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TOBREX 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "NOVARTIS > NOVARTIS SCIENTIFIC OFFICE", "price_egp": 32.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TOBRIN 0.3% EYE.OINT. 5 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 23.0, "pack_count": null, "unit_price": null, "strength_mg": 5000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "AVAZIR 0.3% EYE OINT. 5 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ORCHIDIA PHARMACEUTICAL INDUSTRIES > ORCHIDIA", "price_egp": 26.0, "pack_count": null, "unit_price": null, "strength_mg": 5000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "corneal-abrasion" }, { "id": 507, "generic": "Ofloxacin", "line": 1, "is_adjunct": false, "form": "eye", "strength_mg": null, "adult_dose": "1-2 drops into the affected eye every 2-4 hours for the first 2 days, then 4 times daily. Never longer than 10 days.", "adult_duration": "5-7 days, maximum 10", "dose_source": "Exocin 3 mg/ml Eye Drops SmPC section 4.2 (eMC product 1353)", "rationale": "For a contact lens wearer, where the organism to fear is Pseudomonas. Drops cost 6 EGP, so there is no reason to compromise on cover.", "cautions": [ "The label warns of corneal perforation when a fluoroquinolone drop is used on an eye with an epithelial defect - which is what an abrasion is. Review the eye, and refer if it is not healing.", "A contact lens wearer with an abrasion does not go back into lenses until the eye is healed and reviewed.", "Refer same day for any white infiltrate, hypopyon, or vision that is getting worse - that is keratitis, not an abrasion.", "Recommended that EXOCIN not be used in pregnant women." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "For all ages (1 year and older): one to two drops in the affected eye(s) every two to four hours for the first two days and then four times daily. Safety and effectiveness in infants below the age of one year have not been established.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "QUIFLURO 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 6.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OFLOXIN 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 7.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OFLOXACIN 0.3% EYE DROPS 10 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA TEC", "price_egp": 7.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OFLICIN 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 8.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OFLOSWIX 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CHEMIPHARM", "price_egp": 12.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OCUFLOX 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALEXANDRIA", "price_egp": 19.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OPTIFLOX 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JAMJOOM PHARMACEUTICALS-K.S.A > JAMJOOM PHARMA", "price_egp": 19.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OFLOX 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALLERGAN > SOFICOPHARM", "price_egp": 20.4, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "corneal-abrasion" }, { "id": 509, "generic": "Erythromycin", "line": 1, "is_adjunct": false, "form": "eye", "strength_mg": null, "adult_dose": "Erythromycin ointment, 4 times a day across the 5 days, for a patient who does not wear contact lenses.", "adult_duration": "5 days", "dose_source": "Corneal Abrasion - StatPearls - NCBI Bookshelf - disease-level clinical article (corneal-abrasion-full.txt) for the topical ointment regimen; the systemic paediatric figures are from Egyptian National Drug Formulary - Antimicrobial 2023 (erythromycin monograph), Dosing: Pediatric, general dosing: \"Oral: Base, ethylsuccinate, stearate: 30 to 50 mg/kg/day divided every 6 to 8 hours usually; for severe infection may double dose; maximum daily dose: Mild to moderate infection: 2,000 mg/day; severe infection: 4,000 mg/day\".", "rationale": "Topical antibiotic ointment providing antibiotic cover and ocular lubrication for simple corneal abrasion in non-contact lens wearers.", "cautions": [ "Erythromycin is not obtainable in Egypt in this form. Every erythromycin eye product is absent from the national product list entirely, all 16 oral products are marked withdrawn, and the only three live topical products are acne preparations. Prescribe tobramycin or ofloxacin eye drops instead - both are stocked and cover the same job, tobramycin for a patient who does not wear lenses, ofloxacin for one who does.", "For non-contact lens wearers only; contact lens wearers require anti-pseudomonal coverage (e.g. fluoroquinolone or aminoglycoside).", "Re-evaluate if symptoms persist beyond 3 days." ], "peds_mgkg_low": 30.0, "peds_mgkg_high": 50.0, "peds_max_mg": 2000.0, "peds_basis": "day", "peds_unit": "mg", "peds_note": "General dosing, susceptible infection: Infants, Children, and Adolescents: Oral: Base, ethylsuccinate, stearate: 30 to 50 mg/kg/day divided every 6 to 8 hours usually; for severe infection may double dose; maximum daily dose: Mild to moderate infection: 2,000 mg/day; severe infection: 4,000 mg/day.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 300, "high_mg": 500, "capped": false }, { "weight_kg": 20, "low_mg": 600, "high_mg": 1000, "capped": false }, { "weight_kg": 30, "low_mg": 900, "high_mg": 1500, "capped": false }, { "weight_kg": 40, "low_mg": 1200, "high_mg": 2000, "capped": false } ], "brands": [ { "trade_name": "AKNEMYCIN 2% OINT. 15 GM (N/A)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP > HERMAL-GERMANY", "price_egp": 5.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": false, "discontinued": true, "also_contains": null }, { "trade_name": "ACNI-CARE 2% TOP. GEL. 20 GM (N/A)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA", "price_egp": 6.5, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": false, "discontinued": true, "also_contains": null }, { "trade_name": "ERYTHROCID 200 MG/5ML SUSP. 60ML (N/A)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CID", "price_egp": 5.6, "pack_count": null, "unit_price": null, "strength_mg": 200.0, "exact_strength": true, "exact_form": false, "discontinued": true, "also_contains": null }, { "trade_name": "ERYTHROMYCIN PHARCO 200MG/5ML SUSP. 60ML (N/A)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 7.5, "pack_count": null, "unit_price": null, "strength_mg": 200.0, "exact_strength": true, "exact_form": false, "discontinued": true, "also_contains": null }, { "trade_name": "AKNEMYCIN 2% SOLUTION 25 ML (N/A)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP > HERMAL-GERMANY", "price_egp": 9.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": false, "discontinued": true, "also_contains": null }, { "trade_name": "ETHYRONATE 200MG/5ML SUSP. 100 ML (N/A)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UNIPHARMA CO. > UNIPHARMA", "price_egp": 9.5, "pack_count": null, "unit_price": null, "strength_mg": 200.0, "exact_strength": true, "exact_form": false, "discontinued": true, "also_contains": null }, { "trade_name": "ETHYRONATE 400MG/5ML SUSP. 100 ML (N/A)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UNIPHARMA CO. > UNIPHARMA", "price_egp": 11.75, "pack_count": null, "unit_price": null, "strength_mg": 400.0, "exact_strength": true, "exact_form": false, "discontinued": true, "also_contains": null }, { "trade_name": "ACNI-CARE 2% LOTION 25 ML (N/A)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA", "price_egp": 20.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": false, "discontinued": true, "also_contains": null } ], "condition_id": "corneal-abrasion" }, { "id": 508, "generic": "Sodium hyaluronate", "line": 1, "is_adjunct": true, "form": "eye", "strength_mg": null, "adult_dose": "Instill preservative-free lubricating drops 1-2 drops every 2-4 hours as needed for comfort", "adult_duration": "3-5 days", "dose_source": "No labelled dose - a lubricant appliance, not a licensed medicine; instilled as often as comfort needs", "rationale": "Promotes epithelial re-surfacing and reduces eyelid friction", "cautions": [ "Re-evaluate within 24-48 hours if pain worsens, photophobia increases, or vision degrades.", "Sodium hyaluronate drops are sold as an appliance rather than a licensed medicine, so no regulator has set a dose for them. Use them as often as the eye needs and judge by comfort." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Preservative-free lubricating drops as needed", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "LUBRIVISC 0.1% EYE DROPS 10 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA > HIKMA PHARMA", "price_egp": 32.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "HYALUGRAND 0.2% EYE DROPS 10 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "DELTA GRAND PHARMA", "price_egp": 41.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "HYALOPTIC 0.2% EYE DROPS 10 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 48.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "HYFRESH 0.2% EYE DROPS 10 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JAMJOOM PHARMACEUTICALS", "price_egp": 75.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "XILOIAL MONO EYE DROPS 20 RE-CLOSABLE VIALS * 0.5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "FARMIGEA > HABIB SCIENTIFIC OFFICE", "price_egp": 265.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VISMED MULTI 0.18% EYE DROPS 10 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "TRB CHEMEDICA SA > RHEUMA", "price_egp": 335.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VISMED 0.3% EYE GEL 20 X 0.45 ML SDU", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "TRB CHEMEDICA SA > RHEUMA", "price_egp": 390.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VISMED MULTI 0.3% EYE GEL 10 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "TRB CHEMEDICA SA > RHEUMA", "price_egp": 390.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "corneal-abrasion" } ] }