ALBENDAZOLE
Antiparasitic
Strength400 mg
Formoral.solid
15 mg/kg/day in two divided doses, each dose capped at 600 mg x 8 to 30 days
7.5 mg/kg/dose [child max 600 mg]
(Parenchymal neurocysticercosis in children and adolescents: 7.5 mg/kg per dose twice daily for 8 to 30 days, each dose capped at 600 mg. The grid above is per dose - twice this amount is given in 24 hours.)
| 3kg | 22.5 mg/dose |
|---|---|
| 4kg | 30 mg/dose |
| 5kg | 37.5 mg/dose |
| 6kg | 45 mg/dose |
| 7kg | 52.5 mg/dose |
| 8kg | 60 mg/dose |
| 9kg | 67.5 mg/dose |
| 10kg | 75 mg/dose |
| 11kg | 82.5 mg/dose |
| 12kg | 90 mg/dose |
| 13kg | 97.5 mg/dose |
| 14kg | 105 mg/dose |
| 15kg | 112.5 mg/dose |
| 16kg | 120 mg/dose |
| 17kg | 127.5 mg/dose |
| 18kg | 135 mg/dose |
| 19kg | 142.5 mg/dose |
| 20kg | 150 mg/dose |
| 21kg | 157.5 mg/dose |
| 22kg | 165 mg/dose |
| 23kg | 172.5 mg/dose |
| 24kg | 180 mg/dose |
| 25kg | 187.5 mg/dose |
| 26kg | 195 mg/dose |
| 27kg | 202.5 mg/dose |
| 28kg | 210 mg/dose |
| 29kg | 217.5 mg/dose |
| 30kg | 225 mg/dose |
| 31kg | 232.5 mg/dose |
| 32kg | 240 mg/dose |
| 33kg | 247.5 mg/dose |
| 34kg | 255 mg/dose |
| 35kg | 262.5 mg/dose |
| 36kg | 270 mg/dose |
| 37kg | 277.5 mg/dose |
| 38kg | 285 mg/dose |
| 39kg | 292.5 mg/dose |
| 40kg | 300 mg/dose |
| 41kg | 307.5 mg/dose |
| 42kg | 315 mg/dose |
| 43kg | 322.5 mg/dose |
| 44kg | 330 mg/dose |
| 45kg | 337.5 mg/dose |
| 46kg | 345 mg/dose |
| 47kg | 352.5 mg/dose |
| 48kg | 360 mg/dose |
| 49kg | 367.5 mg/dose |
| 50kg | 375 mg/dose |
Egyptian National Drug Formulary - Antimicrobial 2023 (albendazole monograph, p26)
The formulary lists treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm as an indication for albendazole, and gives the weight-based rule below in the same monograph. Note that the dose and the maximum are HIGHER than for hydatid disease, and that the formulary attaches two conditions to it, both carried into the cautions.
- A STEROID GOES WITH IT FOR THE FIRST WEEK. The formulary states that patients should receive a corticosteroid concurrently for the first week of albendazole therapy: killing the cysts inflames the brain around them.
- AND AN ANTICONVULSANT AS REQUIRED, in the formulary's own words. Seizures are how neurocysticercosis usually presents and how treatment can make it worse.
- THIS IS SPECIALIST TREATMENT. Imaging of the brain, the number and stage of the lesions, and whether the cysts sit outside the brain parenchyma all change what is given and whether a drug should be given at all. Refer. What is set out here is what the drug treatment is, not permission to start it unsupervised.
- Do not give to anyone with a known allergy to albendazole or another benzimidazole.
| Egyptian brand | Manufacturer | Indicative price |
|---|---|---|
| ALBENDAZOLE 400 MG 6 TABS | PHARMA CURE PHARMACEUTICALS > PHARMA CURE | 46.00 EGP (7.67/unit) |
| ANTIZOLE 100MG/5ML SUSP. 30ML? strength differs? different route - not oral solid | ALEXANDRIA | 19.00 EGP |
| ALZENTAL 20MG/ML SUSP. 20ML? strength differs? different route - not oral solid | EIPICO | 21.00 EGP |