Dawaa Reference

acute

Drug-induced dermatitis

Treatment options, dosing, cautions and Egyptian brands from the shipped Dawaa Reference card.

Evidence status

Checked against the sources named below

Sources3 sources

Egyptian National Drug Formulary - Respiratory Medicines 2026, loratadine monograph (respiratory-2026.pdf page index 25, printed p14) · Egyptian National Drug Formulary - Respiratory System 2026 (loratadine monograph) · Al Aboud DM, Nessel TA, Hafsi W. Cutaneous Adverse Drug Reaction. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Bookshelf ID: NBK533000.

Verified against1 document
  • Egyptian National Drug Formulary - Respiratory Medicines 2026, loratadine monograph (respiratory-2026.pdf page index 25, printed p14)

Verified date2026-08

1

LORATADINE

1st line

Strength10 mg

Formoral.solid

Adult dose and duration

10 mg once daily - Not specified in the formulary

Paediatric dose

(Children over 6 years: 10 mg once daily. Children 2 to 6 years: 5 mg once daily. Alternative weight-based dosing for children under 12 years: 30 kg or less, 5 mg once daily; over 30 kg, 10 mg once daily. Under 2 years: safety and efficacy not established.)

Dose by age
2 to under 6 years:5 mg once daily
6 years and over:10 mg once daily
Dose source

Egyptian National Drug Formulary - Respiratory Medicines 2026, loratadine monograph (respiratory-2026.pdf page index 25, printed p14)

Why

A drug eruption is an itchy, often urticarial or morbilliform rash; a standard non-sedating oral antihistamine controls the itch while the causative drug is withdrawn, the same symptomatic role it plays in urticaria.

Cautions
  • Excreted in breast milk; the formulary does not recommend use in breastfeeding women.
  • Renal impairment with creatinine clearance under 30 mL/min: 10 mg every 48 hours
  • Signs of a severe cutaneous adverse reaction - mucosal involvement, blistering, skin sloughing, or systemic symptoms - need emergency referral for possible Stevens-Johnson syndrome or DRESS.
  • Identify and stop the suspected causative drug - this is the definitive treatment; the antihistamine only controls itch while the eruption resolves.
  • Urgent same-day referral if there is mucosal (mouth, eye, genital) involvement, blistering, skin sloughing, or systemic symptoms - these suggest Stevens-Johnson syndrome or DRESS, not a simple exanthematous drug eruption.
  • Document the reaction and the culprit drug clearly in the patient's record/allergy list to prevent re-exposure.
  • Loratadine is non-sedating; use caution in severe hepatic impairment.
Egyptian brands
Egyptian brandManufacturerIndicative price
HISTALONG 10 MG 20 TAB.JEDCO INT. CO. FOR PHARMACEUTICALS17.00 EGP (0.85/unit)
UNILORATADINE 10 MG 20 TABS.UNIPHARMA CO. > UNIPHARMA17.00 EGP (0.85/unit)
SEDCLARIT 10MG 20 TAB.SEDICO19.50 EGP (0.97/unit)
LORATADINE 10MG 10 TAB.MISR25.50 EGP (2.55/unit)
ONY 10 MG 20 TABS.UNIPHARMA51.00 EGP (2.55/unit)
ALLERGETONE 10 MG 20 TABS.MARCYRL PHARMACEUTICAL INDUSTRIES (MPI) > SPLENDID PHARMA66.00 EGP (3.30/unit)
CLARITINE 10MG 20 TAB.SEDICO > BAYER HEALTHCARE110.00 EGP (5.50/unit)
ALLERGIRAZ 10MG 30 DISINTEGRATING TABS.JEDCO INT. CO. FOR PHARMACEUTICALS > ELRAZY PHARMACEUTICALS-EGYPT31.50 EGP
LORANO 5MG/5ML SYRUP 60ML? strength differs? different route - not oral solidMINA PHARM5.00 EGP
UNILORATADINE 5MG/5ML SYRUP 100 ML? strength differs? different route - not oral solidUNIPHARMA CO. > UNIPHARMA9.00 EGP

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.