# Drug-induced dermatitis - Category: acute - Review status: reviewed (every claim checked against a document named on this page) - Sources: Egyptian National Drug Formulary - Respiratory Medicines 2026, loratadine monograph (respiratory-2026.pdf page index 25, printed p14) · Egyptian National Drug Formulary - Respiratory System 2026 (loratadine monograph) · Al Aboud DM, Nessel TA, Hafsi W. Cutaneous Adverse Drug Reaction. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Bookshelf ID: NBK533000. - Verified date: 2026-08 ## Verified against - Egyptian National Drug Formulary - Respiratory Medicines 2026, loratadine monograph (respiratory-2026.pdf page index 25, printed p14) ## Treatment metadata - Loratadine — 10 mg — oral.solid ## Complete treatment card ```text DRUG-INDUCED DERMATITIS Sources: Egyptian National Drug Formulary - Respiratory Medicines 2026, loratadine monograph (respiratory-2026.pdf page index 25, printed p14) · Egyptian National Drug Formulary - Respiratory System 2026 (loratadine monograph) · Al Aboud DM, Nessel TA, Hafsi W. Cutaneous Adverse Drug Reaction. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Bookshelf ID: NBK533000. Review status: REVIEWED against the source listed above (2026-08) 1. LORATADINE [1st line] Adult 10 mg once daily - Not specified in the formulary Peds 2 to under 6 years: 5 mg once daily 6 years and over: 10 mg once daily (Children over 6 years: 10 mg once daily. Children 2 to 6 years: 5 mg once daily. Alternative weight-based dosing for children under 12 years: 30 kg or less, 5 mg once daily; over 30 kg, 10 mg once daily. Under 2 years: safety and efficacy not established.) Source Egyptian National Drug Formulary - Respiratory Medicines 2026, loratadine monograph (respiratory-2026.pdf page index 25, printed p14) Why A drug eruption is an itchy, often urticarial or morbilliform rash; a standard non- sedating oral antihistamine controls the itch while the causative drug is withdrawn, the same symptomatic role it plays in urticaria. Caution Excreted in breast milk; the formulary does not recommend use in breastfeeding women. Renal impairment with creatinine clearance under 30 mL/min: 10 mg every 48 hours Signs of a severe cutaneous adverse reaction - mucosal involvement, blistering, skin sloughing, or systemic symptoms - need emergency referral for possible Stevens-Johnson syndrome or DRESS. Identify and stop the suspected causative drug - this is the definitive treatment; the antihistamine only controls itch while the eruption resolves. Urgent same-day referral if there is mucosal (mouth, eye, genital) involvement, blistering, skin sloughing, or systemic symptoms - these suggest Stevens-Johnson syndrome or DRESS, not a simple exanthematous drug eruption. Document the reaction and the culprit drug clearly in the patient's record/allergy list to prevent re-exposure. Loratadine is non-sedating; use caution in severe hepatic impairment. Egypt HISTALONG 10 MG 20 TAB. JEDCO INT. CO... 17.00 EGP (0.85/unit) UNILORATADINE 10 MG 20 TABS. UNIPHARMA CO.... 17.00 EGP (0.85/unit) SEDCLARIT 10MG 20 TAB. SEDICO 19.50 EGP (0.97/unit) LORATADINE 10MG 10 TAB. MISR 25.50 EGP (2.55/unit) ONY 10 MG 20 TABS. UNIPHARMA 51.00 EGP (2.55/unit) ALLERGETONE 10 MG 20 TABS. MARCYRL PHARM... 66.00 EGP (3.30/unit) CLARITINE 10MG 20 TAB. SEDICO > BAYE... 110.00 EGP (5.50/unit) ALLERGIRAZ 10MG 30 DISINTEGRATING TABS. JEDCO INT. CO. FOR PHARMACEUTICA... 31.50 EGP LORANO 5MG/5ML SYRUP 60ML MINA PHARM 5.00 EGP -> ? strength differs, ? different route - not oral solid UNILORATADINE 5MG/5ML SYRUP 100 ML UNIPHARMA CO. > UNIPHARMA 9.00 EGP -> ? strength differs, ? different route - not oral solid Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy. ``` --- Dawaa Reference is a reference for prescribers, not a medical device, and does not replace clinical judgement. [Privacy policy](/privacy)