{
  "schema_version": 1,
  "kind": "condition",
  "id": "dry-eye",
  "name": "Dry eye",
  "category": "chronic",
  "sources": "Hypromellose Eye Drops BP SmPC sections 4.1-4.4 (eMC product 457) · TFOS DEWS II Management and Therapy Report 2017 · Viscotears Liquid Gel SmPC sections 4.1-4.4 (eMC product 2310)",
  "review_status": "reviewed",
  "verified_against": "Hypromellose Eye Drops BP SmPC sections 4.1-4.4 (eMC product 457) · Viscotears Liquid Gel SmPC sections 4.1-4.4 (eMC product 2310) · Dry Eye Syndrome - disease-level clinical article (dry-eye-syndrome-clinical.txt)",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 613,
      "generic": "Hypromellose",
      "line": 1,
      "is_adjunct": false,
      "form": "eye",
      "strength_mg": null,
      "adult_dose": "One or two drops topically instilled into the eye three times daily as needed, or as directed by a physician.",
      "adult_duration": "long-term as needed",
      "dose_source": "Hypromellose Eye Drops BP SmPC sections 4.1-4.4 (eMC product 457)",
      "rationale": "Direct match - hypromellose artificial tears are the standard first-line treatment for dry eye of any cause.",
      "cautions": [
        "Once a bottle is opened it keeps four weeks, no longer, however much is left in it.",
        "May cause transient blurring of vision on instillation. Do not drive or operate hazardous machinery unless vision is clear.",
        "First-line lubricant for mild-to-moderate dry eye; safe for long-term as-needed use.",
        "Use preservative-free drops if instilling more than 4-6 times daily.",
        "Remove soft contact lenses before instillation; wait at least 15 minutes before reinserting.",
        "If accompanied by dry mouth and joint pain, consider an underlying autoimmune cause (e.g. Sjogren's syndrome) and investigate or refer.",
        "RED FLAG - Eye pain, redness or a change in vision beyond the usual gritty, burning discomfort: rule out corneal involvement or another diagnosis."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "1-2 drops topically instilled into the eye three times daily as needed, or as directed by a physician.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "HYDROBLEND 0.32% EYE DROPS 10*0.5 ML SDU",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "GLOBAL ADVANCED PHARMACEUTICALS (GAP) > MONOPHARMA PHARMACEUTICALS",
          "price_egp": 15.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "GENTEAL EYE DROPS 10 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "NOVARTIS > NOVARTIS SCIENTIFIC OFFICE",
          "price_egp": 18.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "OPTILUBRIC 0.32% EYE DROPS 30*0.5 ML SDU",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EVA PHARMA",
          "price_egp": 96.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "HYDROBLEND 0.32% EYE DROPS 30*0.5 ML SDU",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "GLOBAL ADVANCED PHARMACEUTICALS (GAP) > MONOPHARMA PHARMACEUTICALS",
          "price_egp": 108.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "dry-eye"
    },
    {
      "id": 615,
      "generic": "Referral & safety-netting (no drug therapy)",
      "line": 1,
      "is_adjunct": false,
      "form": null,
      "strength_mg": null,
      "adult_dose": null,
      "adult_duration": null,
      "dose_source": "Dry Eye Syndrome - disease-level clinical article (dry-eye-syndrome-clinical.txt)",
      "rationale": "Carries the referral criteria and warning signs for this condition, which apply whichever treatment is chosen.",
      "cautions": [
        "RED FLAG - Severe/untreated disease can progress to corneal complications (infectious keratitis, ulceration, scarring) causing vision loss - escalate rather than continuing a lubricant alone."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": null,
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [],
      "condition_id": "dry-eye"
    },
    {
      "id": 614,
      "generic": "Carbomer",
      "line": 2,
      "is_adjunct": false,
      "form": "eye",
      "strength_mg": null,
      "adult_dose": "Instil 1 drop of 0.2% eye gel into affected eye(s) 3-4 times daily and at bedtime",
      "adult_duration": null,
      "dose_source": "Viscotears Liquid Gel SmPC sections 4.1-4.4 (eMC product 2310)",
      "rationale": "Higher-viscosity lubricant gel that stays on the ocular surface longer than a standard artificial tear, chosen for more severe or nocturnal dry eye symptoms.",
      "cautions": [
        "Carbomer is a high-viscosity gel providing longer ocular residence time for severe nocturnal symptoms.",
        "May cause temporary blurred vision immediately after application.",
        "Refer to ophthalmologist if corneal ulceration or severe pain occurs.",
        "Soft lenses take up the preservative and discolour: out before the drop, back in no sooner than 15 minutes after.",
        "Once a bottle is opened it keeps four weeks, no longer, however much is left in it.",
        "It blurs vision for a while after each drop. Wait until it clears before driving.",
        "In case of any additional local ocular treatment (eg glaucoma therapy) there should be an application interval of at least 5 minutes between the two medications, Viscotears Liquid Gel always should be the last medication instilled."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Instil 1 drop 3-4 times daily in children",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "VIDISEC EYE GEL 10 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MINA PHARM > DR.MANN-GERMANY",
          "price_egp": 13.2,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 10000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "THILOTEARS 3 MG EYE GEL 10 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "ALCON > NOVARTIS SCIENTIFIC OFFICE",
          "price_egp": 19.2,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 3.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "OCCUPLUS EYE GEL DROPS 20 X 0.6ML SDU",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "COC Farmaceutici > RX HEALTHCARE",
          "price_egp": 300.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "dry-eye"
    }
  ]
}