# Dyslipidemia - Category: chronic - Review status: reviewed (every claim checked against a document named on this page) - Sources: ESC/EAS Dyslipidaemias 2019 · Egyptian National Drug Formulary - Cardiovascular 2024 (fenofibrate monograph) · Atorvastatin 20 mg film-coated tablets SmPC section 4.2 Posology and method of administration (eMC product 13673) · Rosuvastatin 10 mg film coated tablets SmPC section 4.2 Posology and method of administration (eMC product 14430) - Verified date: 2026-08 ## Verified against - ESC/EAS Dyslipidaemias 2019 - Egyptian National Drug Formulary - Cardiovascular 2024 (fenofibrate monograph) - Atorvastatin 20 mg film-coated tablets SmPC section 4.2 Posology and method of administration (eMC product 13673) - Rosuvastatin 10 mg film coated tablets SmPC section 4.2 Posology and method of administration (eMC product 14430) ## Treatment metadata - Atorvastatin — 20 mg — oral.solid - Rosuvastatin — 10 mg — oral.solid - Ezetimibe — 10 mg — oral.solid - Fenofibrate — 160 mg — oral.solid ## Complete treatment card ```text DYSLIPIDEMIA Sources: ESC/EAS Dyslipidaemias 2019 · Egyptian National Drug Formulary - Cardiovascular 2024 (fenofibrate monograph) · Atorvastatin 20 mg film-coated tablets SmPC section 4.2 Posology and method of administration (eMC product 13673) · Rosuvastatin 10 mg film coated tablets SmPC section 4.2 Posology and method of administration (eMC product 14430) Review status: REVIEWED against 4 sources listed above (2026-08) IS IT THIS? - reference only, to read alongside your own examination SYMPTOMS - what the patient reports (6) - Lower limb claudication - pain or cramping on walking that eases with rest - suggests peripheral artery disease from dyslipidemia [claudication · muscle cramps] - Angina - chest pain brought on by exertion or emotional stress, radiating to the neck, jaw, shoulders, or back [chest pain] - Sudden weakness, slurred speech, or visual disturbance can signal a TIA or stroke from atherosclerosis [slurred speech] - Blurred vision can occur with lipemia retinalis in severe hypertriglyceridemia [blurred vision] - It usually produces nothing the patient can feel, and turns up on a blood test - The primary form is inherited, from mutations that affect how lipids are handled; the secondary form is acquired, from the way a person lives or from another illness SIGNS - what you find (3) - Yellowish fat deposits (xanthomas) on the eyelids, palms, or tendons point to high cholesterol or triglycerides - A grey or white ring at the corneal margin - arcus senilis - reflects high blood cholesterol - A milky appearance of the retinal vessels on fundoscopy reflects very high triglyceride levels TESTS (6) - A fasting lipid panel measuring total cholesterol, LDL, HDL, and triglycerides is the primary evaluation tool - LDL cholesterol under 100 mg/dL is optimal, rising through borderline-high and high categories - Triglycerides are normal below 150 mg/dL and borderline-high from 150 to 199 mg/dL - HDL should be over 40 mg/dL in a man and over 50 in a woman - Total cholesterol should sit under 200 mg/dL - Total cholesterol is LDL plus HDL plus half the triglyceride level, and a high one flags the risk of heart disease and stroke IF NOT THIS - what else fits (5) - Nephrotic syndrome is listed as a differential for dyslipidemia - Biliary obstruction is listed as a differential for dyslipidemia - Hypothyroidism is listed as a differential for dyslipidemia - Pregnancy is listed as a differential for dyslipidemia - Certain drugs - oral estrogens, glucocorticoids, tamoxifen, thiazides - are listed as a differential Source StatPearls "Dyslipidemia" - disease-level clinical article Status traced to the source above 1. ATORVASTATIN [1st line] Adult 10-20 mg once daily (any time of day), titrate up to 80 mg daily - long-term Peds Specialist referral for pediatric familial hypercholesterolemia Choice Alternatives. Atorvastatin carries the larger outcome evidence base and is the cheaper to start (12-128 EGP against 26-368). Source Atorvastatin 20 mg film-coated tablets SmPC section 4.2 Posology and method of administration (eMC product 13673) Why HMG-CoA reductase inhibitor (statin) that lowers LDL cholesterol by blocking hepatic cholesterol synthesis, used to reduce cardiovascular risk in dyslipidemia. Caution CONTRAINDICATED in pregnancy and breastfeeding. Monitor LFTs before starting and at 12 months. Muscle pain requires creatine kinase check. Caution in heavy alcohol use or hepatic disease. Egypt ANTICHOL 20 MG 10 F.C. TAB. JEDCO INT. CO... 14.40 EGP (1.44/unit) LIRIMAR 20 MG 10 CAPS. RIVA PHARMA S... 15.00 EGP (1.50/unit) LIPOVAST 20MG 7 F.C.TAB. MISR 11.50 EGP (1.64/unit) SIGMALIP 20 MG 10 F.C.TAB. SIGMA 24.00 EGP (2.40/unit) LIPOSEDRA 20 MG 30 F.C.TABS. DELTA PHARMA ... 111.00 EGP (3.70/unit) ATOR 20 MG 10 F.C.TABS. EIPICO 79.00 EGP (7.90/unit) ATCOLIPOX 20 MG 30 CHEW. TABS. ATCO PHARMA 72.00 EGP HIPOLIXAVAST 20 MG 30 CHEW. TABS. EGPI 127.50 EGP 2. ROSUVASTATIN [1st line] Adult 5-10 mg once daily, titrate to 20-40 mg daily - long-term Peds Specialist referral in pediatric dyslipidemia Source Rosuvastatin 10 mg film coated tablets SmPC section 4.2 Posology and method of administration (eMC product 14430) Why Alternative HMG-CoA reductase inhibitor (statin) for LDL cholesterol lowering in dyslipidemia, chosen instead of atorvastatin based on individual tolerability, drug interactions, or the intensity of LDL lowering needed. Caution CONTRAINDICATED in pregnancy and breastfeeding. The 40 mg dose is contraindicated in severe renal impairment. Monitor LFTs and muscle symptoms. Caution in renal impairment. Egypt ROSUMOP 10MG 14 F.C. TABS. MINA PHARM > ... 25.50 EGP (1.82/unit) VINAPOTEX 10 MG 14 F.C TABS RAMEDA EGYPT ... 36.00 EGP (2.57/unit) NAPLEMA 10 MG 30 F.C.TABS. NAPCO 77.25 EGP (2.58/unit) ROSUVALING 10 MG 28 TABLETS UTOPIA PHARMA 100.00 EGP (3.57/unit) NEXIROZOVA 10 MG 28 F.C. TABS. ZETA PHARMA 116.00 EGP (4.14/unit) JUSTECHOL 10 MG 14 F.C. TABS. AUG PHARMA 74.00 EGP (5.29/unit) CRESTOR 10 MG 28 F.C.TABS. IPR PHARMACEU... 368.00 EGP (13.14/unit) EPIROVASTIN 10 MG 14 SCORED F.C. TABS. EIPICO 56.00 EGP 3. EZETIMIBE [2nd line] Adult 10 mg once daily, monotherapy or add-on to statin - long-term Peds Specialist referral in children Source ESC/EAS Dyslipidaemias 2019 Why Cholesterol absorption inhibitor that blocks intestinal uptake of dietary and biliary cholesterol; used as monotherapy or added to a statin when further LDL lowering is needed beyond what the statin achieves alone. Caution Monitor LFTs when combined with a statin. Caution in moderate to severe hepatic impairment. GI disturbance and fatigue have been reported. Egypt LOWTIMIB 10 MG 10 TAB. PHAROPHARMA 11.50 EGP (1.15/unit) CHOLSTOP 10MG 30 TAB MUP 41.00 EGP (1.37/unit) EZETIMIBE 10MG 10 TAB. BORG 14.40 EGP (1.44/unit) LIPIDNORM 10 MG 10 TAB. OCTOBER PHARMA 14.40 EGP (1.44/unit) ZETAMIBE 10 MG 10 TAB. ADWIA 34.80 EGP (3.48/unit) ZETLIP 10MG 10 TAB. BIORIGINAL IN... 35.00 EGP (3.50/unit) CHOLETIMB 10 MG 14 TABS. MARCYRL PHARM... 65.00 EGP (4.64/unit) EZETROL 10MG 7 TAB. MERCK SHARP &... 90.00 EGP (12.86/unit) 4. FENOFIBRATE [3rd line] Adult 160 mg once daily with meals for severe hypertriglyceridemia - long-term Peds Not recommended in children Source Egyptian National Drug Formulary - Cardiovascular 2024 (fenofibrate monograph) Why Fibrate that activates PPAR-alpha to lower triglycerides, used for severe hypertriglyceridemia that is not adequately addressed by a statin, since statins primarily target LDL rather than triglycerides. Caution Monitor renal function and LFTs. Fenofibrate dosing depends on the formulation - the formulary gives 200 mg for the capsule and directs you to the product leaflet. The 160 mg here is the tablet strength. There is a risk of cholelithiasis and gallbladder disease. There is an increased risk of myopathy when combined with statins. Egypt LIPANTHYL SUPRA 160MG 30 F.C. TABS. MINA PHARM > ABBOTT LABO... 141.00 EGP (4.70/unit) Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy. ``` --- Dawaa Reference is a reference for prescribers, not a medical device, and does not replace clinical judgement. [Privacy policy](/privacy)