Dawaa Reference

chronic

Ebola Virus Disease

Treatment options, dosing, cautions and Egyptian brands from the shipped Dawaa Reference card.

Evidence status

Checked against the sources named below

Sources3 sources

Ebola Virus Disease - StatPearls (NCBI Bookshelf NBK560579) - https://www.ncbi.nlm.nih.gov/books/NBK560579/ · ICPC-3 (WONCA International Classification of Primary Care, 3rd edition) class AD14.03 - condition scope only, no dose · No dose - referral pathway, no medicine given in primary care

Verified against1 document
  • No dose - referral pathway, no medicine given in primary care

Verified date2026-08

Presentation reference

Is it this?

Reference only, to read alongside your own examination.

Symptoms — what the patient reports (5)

  • Sudden fever with malaise, headache, poor appetite, and muscle aches marks the onset [fever · headache · malaise · muscle pain · poor appetite]
  • Nausea, abdominal pain, vomiting, and diarrhea follow the initial fever phase [abdominal pain · diarrhoea · fever · nausea · vomiting]
  • Red eyes, sore throat, and hiccups can also occur [hiccups · sore throat]
  • Breathlessness, cough, confusion, and prostration develop as the illness advances [breathlessness · confusion · cough]
  • Travel to an Ebola outbreak area within 2 to 21 days before symptom onset is a key exposure history

Signs — what you find (3)

  • A maculopapular rash with bleeding from mucous membranes, skin, eyes, nose, or ears can appear later in the early phase [bleeding · rash]
  • Fluid losses can average 3 to 5 liters a day and reach as much as 10 liters daily
  • Patients later in the illness, with higher viral loads, may present severely ill and in shock [shock]

Tests (7)

  • A complete blood count evaluates hemoglobin, platelets, and white cell counts
  • A metabolic panel can show acute kidney injury, electrolyte derangements, high liver enzymes, and low blood sugar
  • A coagulation profile - PT, aPTT, fibrinogen, INR - is monitored to detect coagulopathy
  • RT-PCR testing for the viral nucleoprotein or glycoprotein is the most sensitive diagnostic test
  • Rapid lateral flow tests show a pooled sensitivity of 85% and specificity of 95% against RT-PCR
  • Ebola IgM cannot be detected until at least 6 days after symptom onset
  • Chest x-ray is used to check for pulmonary edema from capillary leak syndrome

If not this — what else fits (3)

  • Marburg virus, Lassa fever, Crimean-Congo hemorrhagic fever, dengue, Rift Valley fever, and other bunyaviruses can also cause hemorrhage in a febrile patient
  • Illnesses with a similar early prodrome include malaria, typhoid fever, measles, leptospirosis, influenza, and COVID-19
  • Gastroenteritis from shigella, rotavirus, or norovirus can mimic the early gastrointestinal symptoms

SourceStatPearls "Ebola Virus Disease" - disease-level clinical article

Presentation findings are traced to the source above.

1

NO DRUG THERAPY IN PRIMARY CARE (RECOGNITION & REFERRAL)

1st line
Adult dose and duration

Severe viral haemorrhagic fever with high mortality and no local transmission risk in Egypt. A returning traveller from an active outbreak country with fever must be isolated and reported immediately rather than worked up as routine fever. - Refer

Paediatric dose

Children follow the same pathway: recognise and refer. No primary-care medicine is implied.

Dose source

No dose - referral pathway, no medicine given in primary care

Why

Severe viral haemorrhagic fever with high mortality and no local transmission risk in Egypt. A returning traveller from an active outbreak country with fever must be isolated and reported immediately rather than worked up as routine fever.

Cautions
  • Not endemic in Egypt. Relevant to a returning traveller or an imported case; consider the travel history before anything else.
  • No medicine is prescribed for this in primary care - this entry is for recognition and referral. Anything given is decided by the service it is referred to.
  • RED FLAG - Fever plus travel to an active Ebola outbreak area in the past 21 days, or bleeding or haemorrhagic signs: a suspected case needs immediate isolation and health-authority notification, not outpatient management.

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.