# Facial Pain

- Category: acute
- Review status: reviewed (every claim checked against a document named on this page)
- Sources: Egyptian National Drug Formulary - nervous-2025.pdf, Carbamazepine monograph (chapter PDF p27) · Shankar Kikkeri N, Nagalli S. Trigeminal Neuralgia. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; last update March 3, 2024.
- Verified date: 2026-08

## Verified against

- Egyptian National Drug Formulary - nervous-2025.pdf, Carbamazepine monograph (chapter PDF p27)
- Shankar Kikkeri N, Nagalli S. Trigeminal Neuralgia. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; last update March 3, 2024.

## Treatment metadata

- Carbamazepine — oral.solid

## Complete treatment card

```text
FACIAL PAIN
Sources: Egyptian National Drug Formulary - nervous-2025.pdf, Carbamazepine monograph (chapter PDF
         p27) · Shankar Kikkeri N, Nagalli S. Trigeminal Neuralgia. In: StatPearls [Internet].
         Treasure Island (FL): StatPearls Publishing; last update March 3, 2024.
Review status: REVIEWED against 2 sources listed above  (2026-08)

1. CARBAMAZEPINE                                          [1st line]
   Adult    Initial 200-400 mg daily, increased gradually until pain-free, usually 200 mg 3-4 times
            daily; up to 1200 mg daily may be needed in some cases, then tapered to the lowest
            possible dose that maintains control. Elderly: initial 100 mg twice daily. - As
            directed; long-term at the lowest effective maintenance dose once pain is controlled.
   Peds     Trigeminal neuralgia is essentially an adult/older-adult condition; the formulary's
            paediatric carbamazepine dosing is for epilepsy, not facial pain, and is not reproduced
            here.
   Source   Egyptian National Drug Formulary - nervous-2025.pdf, Carbamazepine monograph (chapter
            PDF p27)
   Why      Carbamazepine is the guideline first-line drug specifically for trigeminal neuralgia,
            one of the recognised causes within the broad 'facial pain' symptom code; it is not
            appropriate for facial pain from other causes.
   Caution  Only appropriate for the specific pattern of trigeminal neuralgia (brief, electric-
            shock-like, touch-triggered unilateral facial pain) - not for facial pain from dental,
            sinus, or other causes.
            There is a rare but serious risk of Stevens-Johnson syndrome/toxic epidermal necrolysis
            and agranulocytosis - stop immediately and seek care if rash or fever develops.
            Many drug interactions (it is a strong enzyme inducer) - check other medications.
            Avoid in pregnancy where possible - associated with neural tube defects.
            Facial pain with jaw claudication or visual change in an older adult needs urgent
            referral for possible giant cell arteritis, not carbamazepine.
            Facial swelling or fever suggests a dental/sinus abscess needing antibiotics and
            dental/ENT referral, not carbamazepine.
   Egypt    CARBAMAZEPIN 200MG 10 TAB.U.S.P.33 SEDICO                           3.00 EGP (0.30/unit)
            CARBAMAZEPINE 200MG XR 10 TAB.   SIGMA                4.00 EGP (0.40/unit)
            TONOCLONE 200MG 30 TAB.          UP PHARMA           13.50 EGP (0.45/unit)
            TONOCLONE RETARD 400MG C.R. 10 F.C. TAB. UP PHARMA                  8.50 EGP (0.85/unit)
            CARBAPEX 200 MG CR 30 TABS.      MULTI-APEX          81.00 EGP (2.70/unit)
            EPIMAZEPINE CR 200 MG 10 CONTROLLED RELEASE F.C. TABS. EIPICO                   6.00 EGP
            NEUROTOP RETARD 300MG 100 S.R. TAB. GEROT PHARMA > B.P PHARMA                 410.00 EGP
            NEUROTOP RETARD 600MG 100 S.R. TAB. GEROT PHARMA > B.P PHARMA                 720.00 EGP
            ALEXTOL 100MG/5ML ORAL SUSP. 100ML ALEXANDRIA                                   7.50 EGP
                -> ? strength differs, ? different route - not oral solid
            ARBATEG 2% SUSP. 100 ML          MEDIZEN PHARM...    35.00 EGP
                -> ? strength differs, ? different route - not oral solid

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.
```

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Dawaa Reference is a reference for prescribers, not a medical device, and does not replace clinical judgement.

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