# Bacterial Food Poisoning (Toxin Gastroenteritis)

- Category: infectious
- Review status: reviewed (every claim checked against a document named on this page)
- Sources: Egyptian National Drug Formulary - Gastrointestinal 2025, hyoscine-N-butyl bromide monograph (printed page 46, endf-git.txt), which gives adult oral dosing as "Initial: 10 mg three times daily" and "Dose can be increased up to 20 mg four times daily if necessary", and states "Pediatric dosing (6-12 years) Oral: 10 mg three times daily." · CDC Foodborne Illness Guidelines · Egyptian National Drug Formulary, GI 2024, hyoscine-N-butyl bromide monograph (printed pp. 45-46) · WHO. The treatment of diarrhoea: a manual for physicians and other senior health workers, 4th rev. Geneva: WHO; 2005 · WHO/UNICEF reduced-osmolarity oral rehydration salts (245 mOsm/L), recommended since 2002
- Verified date: 2026-08

## Verified against

- Egyptian National Drug Formulary - Gastrointestinal 2025, hyoscine-N-butyl bromide monograph (printed page 46, endf-git.txt), which gives adult oral dosing as "Initial: 10 mg three times daily" and "Dose can be increased up to 20 mg four times daily if necessary", and states "Pediatric dosing (6-12 years) Oral: 10 mg three times daily."
- Egyptian National Drug Formulary, GI 2024, hyoscine-N-butyl bromide monograph (printed pp. 45-46)
- WHO. The treatment of diarrhoea: a manual for physicians and other senior health workers, 4th rev. Geneva: WHO; 2005

## Treatment metadata

- ORS — oral.liquid
- Hyoscin-N-butylbromid — 10 mg — oral.solid

## Complete treatment card

```text
BACTERIAL FOOD POISONING (TOXIN GASTROENTERITIS)
Sources: Egyptian National Drug Formulary - Gastrointestinal 2025, hyoscine-N-butyl bromide
         monograph (printed page 46, endf-git.txt), which gives adult oral dosing as "Initial: 10 mg
         three times daily" and "Dose can be increased up to 20 mg four times daily if necessary",
         and states "Pediatric dosing (6-12 years) Oral: 10 mg three times daily." · CDC Foodborne
         Illness Guidelines · Egyptian National Drug Formulary, GI 2024, hyoscine-N-butyl bromide
         monograph (printed pp. 45-46) · WHO. The treatment of diarrhoea: a manual for physicians
         and other senior health workers, 4th rev. Geneva: WHO; 2005 · WHO/UNICEF reduced-osmolarity
         oral rehydration salts (245 mOsm/L), recommended since 2002
Review status: REVIEWED against 3 sources listed above  (2026-08)

1. ORS                                                    [1st line]
   Adult    Drink 200-400 mL after each loose stool, or as much as desired to maintain hydration. x
            24-48 hours until symptoms resolve
   Peds     Give 50-100 mL after each watery stool in young children
   Source   WHO. The treatment of diarrhoea: a manual for physicians and other senior health
            workers, 4th rev. Geneva: WHO; 2005
   Why      Oral rehydration solution replaces the fluid and electrolyte losses from bacterial
            toxin-mediated gastroenteritis; fluid replacement is the mainstay of treatment, since
            the illness is usually self-limiting and antibiotics are not recommended for this type
            of food poisoning.
   Caution  Never make the solution up in less water than the pack states. A five-fold concentrated
            ORS given to a dehydrated patient causes hypernatraemia, and an infant is the one least
            able to survive it.
            Mainstay of treatment is fluid replacement; preformed toxin illness resolves
            spontaneously in 1-2 days.
            Empirical antibiotics are NOT recommended for simple emetic/diarrhoeal toxin food
            poisoning.
            Seek emergency care if bloody diarrhoea, high fever, or signs of severe dehydration
            present.
            Use the reduced-osmolarity formulation (sodium 75, glucose 75, potassium 20, citrate 10,
            chloride 65 mmol/L; 245 mOsm/L). WHO replaced the older 311 mOsm/L formula in 2002 for
            diarrhoea of any cause at any age - it cuts stool output and vomiting.
   Egypt    GLUCOHYDRAN 10 SACHET.           ARAB DRUG COM...     1.75 EGP
            REHYDRAN N 10 SACHET             CID                  4.50 EGP
            REHYDRO ZINC 10 SACHETS          CID                  7.00 EGP
            ORS 20 SACHETS                   PHAROPHARMA         40.00 EGP
            ELECTRO MASH SYRUP 200 ML        MASH PREMIERE       60.00 EGP
            FLEXOLYTE ORAL REHYDRATION SOL. 240 ML KEMPETRO FOR CHEMICAL INDUSTRIES        65.00 EGP
            HERO ORS 200 ML                  HERO > HERO M...   120.00 EGP
            SANSO ORS SYRUP 140 ML           AUG PHARMA         400.00 EGP

2. HYOSCIN-N-BUTYLBROMID                                  [add-on - not a substitute]
   Adult    10-20 mg 3-4 times daily as needed for painful abdominal cramps x 1-2 days as needed
   Peds     6 to 12 years: 10 mg three times daily as needed. Not recommended under 6 years.
            (Children 6-12 years: 10 mg 3 times daily as needed. Not recommended under 6 years)
   Source   Egyptian National Drug Formulary - Gastrointestinal 2025, hyoscine-N-butyl bromide
            monograph (printed page 46, endf-git.txt), which gives adult oral dosing as "Initial: 10
            mg three times daily" and "Dose can be increased up to 20 mg four times daily if
            necessary", and states "Pediatric dosing (6-12 years) Oral: 10 mg three times daily."
   Why      Antispasmodic for acute cramping abdominal pain
   Caution  Avoid in paralytic ileus, narrow-angle glaucoma, or severe ulcerative colitis.
            Anticholinergic side effects include dry mouth, blurred vision, and tachycardia.
            Also barred by: myasthenia gravis, megacolon, and any mechanical narrowing or
            obstruction of the gut.
            Not a drug to take every day indefinitely. If the cramps keep coming back, the job is to
            find out why, not to keep prescribing the antispasmodic.
            The injection is licensed for adults only, 20 mg repeated after half an hour if needed,
            never past 100 mg in a day. Children get the oral form.
   Egypt    NU-SPASM 10 MG 20 TABS.          EIPICO               4.00 EGP (0.20/unit)
            BUTACID 10MG 20 TAB.             CID                 20.00 EGP (1.00/unit)
            SPASMOCIN 10MG 20 TAB.           MEMPHIS             34.00 EGP (1.70/unit)
            BUSCOPAN 10 MG 20 SUGAR C.TABS.  SERVIER > Ope...    56.00 EGP
            SPASMOCIN 100MG/100ML SYRUP 120ML MEMPHIS                                       3.85 EGP
                -> ? strength differs, ? different route - not oral solid
            FARCORELAXIN 1MG/ML SYRUP 120ML  PHARCO               4.50 EGP
                -> ? strength differs, ? different route - not oral solid

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.
```

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Dawaa Reference is a reference for prescribers, not a medical device, and does not replace clinical judgement.

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