Dawaa Reference

chronic

Gastritis

Treatment options, dosing, cautions and Egyptian brands from the shipped Dawaa Reference card.

Evidence status

Checked against the sources named below

Sources4 sources

ACG Clinical Guideline: Management of Dyspepsia 2017 · Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (lansoprazole monograph) · Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (rabeprazole monograph) · Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (omeprazole monograph)

Verified against4 documents
  • Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (omeprazole monograph)
  • Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (lansoprazole monograph)
  • Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (rabeprazole monograph)
  • Gastritis - disease-level clinical article (gastritis-clinical.txt)

Verified date2026-08

Presentation reference

Is it this?

Reference only, to read alongside your own examination.

Symptoms — what the patient reports (6)

  • Acute gastritis tends to start suddenly with epigastric pain, bloating, nausea, and vomiting that settles on its own [abdominal distension · abdominal pain · epigastric pain · nausea · vomiting]
  • Symptom severity does not track with biopsy findings, and H pylori gastritis can stay silent while it progresses
  • H pylori dyspepsia is confirmed retrospectively by symptom improvement after eradication, which can take up to 6 months [indigestion]
  • Autoimmune gastritis is usually silent and turns up incidentally through pernicious, megaloblastic, or iron-deficiency anemia [anaemia]
  • When autoimmune gastritis does cause symptoms, most patients report fullness or discomfort after meals
  • It frequently clusters with other autoimmune conditions, especially thyroid disease, plus Addison disease, myasthenia gravis, and vitiligo

Tests (9)

  • Endoscopy with biopsy for histopathology is the gold-standard test for confirming gastritis
  • Endoscopy is not required to diagnose functional dyspepsia, but testing for H pylori should still be done
  • New symptoms at an older age, weight loss, bleeding, dysphagia, an abdominal mass, fever, or family history of GI cancer are alarm signs
  • Under age 60 with dyspepsia and no family history of gastric cancer, endoscopy to exclude malignancy is not advised
  • Urea breath testing or stool antigen testing detects H pylori, and retesting after treatment should wait 4 to 6 weeks post-therapy
  • Patients 60 or older with dyspepsia should get endoscopy with histology to assess for gastritis
  • Autoimmune gastritis diagnosis rests partly on finding atrophic changes affecting the stomach body and fundus
  • Anti-parietal cell antibodies are sensitive but not specific, since H pylori infection also raises them, while anti-intrinsic-factor antibodies are highly specific
  • Atrophic gastritis looks pale with visible vessels and flattened folds on endoscopy, detected with high sensitivity by narrow-band imaging

If not this — what else fits (8)

  • Functional dyspepsia
  • Peptic ulcer disease
  • Gastric cancer
  • Cholecystitis
  • Zollinger-Ellison syndrome
  • Pancreatitis
  • Myocardial ischemia mimicking gastritis pain
  • Celiac disease

SourceStatPearls "Gastritis" - disease-level clinical article

Presentation findings are traced to the source above.

1

OMEPRAZOLE

1st line

Strength20 mg

Formoral.solid

Adult dose and duration

20 mg once daily before a meal x 4-8 weeks

Paediatric dose

Specialist pediatric gastroenterology use only

Choice

Alternatives. Both are proton pump inhibitors of equivalent effect; omeprazole is the cheaper and most widely stocked.

Dose source

Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (omeprazole monograph)

Why

PPI therapy is first-line for NSAID-induced and reactive gastritis; if H. pylori positive, eradicate it.

Cautions
  • For NSAID-induced gastritis, stop the offending NSAID.
  • For H. pylori-associated gastritis, cross-refer to the H. pylori eradication regimen.
  • Distinguish from functional dyspepsia (gastritis implies mucosal inflammation visible on endoscopy).
Egyptian brands
Egyptian brandManufacturerIndicative price
OMEGASTAZOLE 20MG 14 CAPS.RIVA PHARMA S.A.E.18.00 EGP (1.29/unit)
OMEPRAL 20MG 14 CAPS.MEMPHIS32.00 EGP (2.29/unit)
RISEK 20 MG 28 CAPS.JULPHAR75.00 EGP (2.68/unit)
OMISEC 20MG 14CAPS.THE UNITED PHARMACEUTICALS CO LTD-JORDAN > MODERN PHARMA42.00 EGP (3.00/unit)
EPIRAZOLE 20MG 14CAPS.EIPICO44.00 EGP (3.14/unit)
OMEPAK 20 MG 14 CAPS.SEDICO50.00 EGP (3.57/unit)
RISEK 20 MG 14 CAPS.JULPHAR57.00 EGP (4.07/unit)
NAPIZOLE 20MG 14 CAPS.GLOBAL NAPI PHARMACEUTICALS62.00 EGP (4.43/unit)
2

LANSOPRAZOLE

1st line

Strength30 mg

Formoral.solid

Adult dose and duration

30 mg once daily in the morning at least 30 minutes before food; 15 mg once daily where the purpose is prophylaxis of NSAID-associated gastroduodenal injury in a patient over 65 or with a previous ulcer x 4 weeks for symptom control, up to 8 weeks if gastric ulceration is present; up to 12 weeks for NSAID prophylaxis

Paediatric dose

(Avoid under 1 year. Children 11 years and under: 15 mg once daily if 30 kg or less, 30 mg once daily if over 30 kg. Children 12 years and over: 15 mg once daily.)

Dose by age
1 to 11 years:15 mg once daily at 30 kg or less; 30 mg once daily over 30 kg. Avoid under 1 year.
12 years and over:15 mg once daily
Dose source

Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (lansoprazole monograph)

Why

17 live products and the cheapest widely stocked alternative to omeprazole. The 15 mg NSAID-prophylaxis dose is the one most gastritis presentations in Egyptian primary care actually need, because NSAID use is the commonest identifiable cause.

Cautions
  • Do not exceed 30 mg daily in the elderly unless there is a clear clinical reason - clearance is reduced.
  • 15 mg daily in severe hepatic impairment (Child-Pugh C)
  • Stop and reconsider if severe or persistent diarrhoea develops - colitis and Clostridioides difficile are reported.
  • Long-term use is associated with hypomagnesaemia, vitamin B12 deficiency, fundic gland polyps and fracture risk.
  • Stop for any rash on sun-exposed skin with joint pain - subacute cutaneous lupus erythematosus is a recognised PPI reaction.
  • Orodispersible tablets must not be crushed or chewed.
Egyptian brands
Egyptian brandManufacturerIndicative price
LORAL 30MG 10 CAPS.PHARCO30.00 EGP (3.00/unit)
GASTROCURE 30MG 10 CAPS.ALFACURE PHARMACEUTICALS33.60 EGP (3.36/unit)
ZOLLIPAK 30MG 10 CAPSSEDICO33.60 EGP (3.36/unit)
LOPRAL 30MG 5 CAPS.UP PHARMA27.50 EGP (5.50/unit)
LANTANON 30MG 10 CAPS.UNIPHARMA CO. > UNIPHARMA57.00 EGP (5.70/unit)
ZALLANZ 30 MG 20 DELAYED REL. CAPS.EL-OBOUR60.00 EGP
ZALLANZ 30 MG 30 DELAYED REL. CAPS.EL-OBOUR90.00 EGP
LANSOFAST 30 MG 30 ORO-DISPERSIBLE TABSNAPCO > DELPHI PHARMA174.00 EGP
3

REFERRAL & SAFETY-NETTING (NO DRUG THERAPY)

1st line
Dose source

Gastritis - disease-level clinical article (gastritis-clinical.txt)

Why

Carries the referral criteria and warning signs for this condition, which apply whichever treatment is chosen.

Cautions
  • RED FLAG - Alarm signs (weight loss, bleeding, dysphagia, abdominal mass, persistent vomiting, family history of UGI cancer) require urgent investigation or endoscopy.
4

RABEPRAZOLE

2nd line

Strength20 mg

Formoral.solid

Adult dose and duration

20 mg once daily in the morning; 10 mg once daily is adequate for maintenance in many patients x 4-8 weeks, then step down to 10 mg daily or stop

Paediatric dose

Not recommended in children - the formulary states there are insufficient safety and efficacy data at any paediatric age.

Dose source

Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (rabeprazole monograph)

Why

18 live products. Needs no dose reduction in renal impairment and only a modest one in severe liver disease, which makes it a practical PPI in a comorbid patient.

Cautions
  • The formulary states rabeprazole is contraindicated in pregnancy and not recommended in breastfeeding - use omeprazole instead in a pregnant patient.
  • Severe hepatic impairment (Child-Pugh C): use 10 mg with caution.
  • Monitor magnesium at baseline and periodically if the patient is also on digoxin or a diuretic.
  • No dose change is needed in renal impairment.
  • Long-term PPI cautions apply: Clostridioides difficile, B12 deficiency, fracture risk.
Egyptian brands
Egyptian brandManufacturerIndicative price
RABEGERDAZOLE 20 MG 21 TABS.AL ROWAD PHARMACEUTICAL INDUSTRIAL CO.40.50 EGP (1.93/unit)
RABEPRAZOLE 20 MG 14 TABS.GLOBAL NAPI PHARMACEUTICALS > SANOFI31.20 EGP (2.23/unit)
PACREDO 20 MG 30 F.C. TABS.MARCYRL PHARMACEUTICAL INDUSTRIES (MPI) > SPLENDID PHARMA121.50 EGP (4.05/unit)
BEPRA 20MG 21 F.C. TAB.GLOBAL NAPI PHARMACEUTICALS154.50 EGP (7.36/unit)
IDIZOLE 20MG 7 ENTERIC COATED TAB.GLAXO SMITHKLINE19.20 EGP
HYGIGASTIN 20 MG 14 ENTERIC COATED TABS.MEDIZEN PHARMACEUTICAL INDUSTRIES > HYGINT PHARMACEUTICALS-EGYPT22.00 EGP
RABGERD 20 MG 14 E.C. TABS.EGPI > TRUE INTERNATIONAL PHARMA70.00 EGP
PATRIMAC 20 MG 28 E.C.TABS.ALROWAD FOR PHARMACEUTICAL INDUSTRIES > AI AIN PHARAM166.00 EGP

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.