{ "schema_version": 1, "kind": "condition", "id": "gastritis", "name": "Gastritis", "category": "chronic", "sources": "ACG Clinical Guideline: Management of Dyspepsia 2017 · Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (lansoprazole monograph) · Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (rabeprazole monograph) · Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (omeprazole monograph)", "review_status": "reviewed", "verified_against": "Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (omeprazole monograph) · Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (lansoprazole monograph) · Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (rabeprazole monograph) · Gastritis - disease-level clinical article (gastritis-clinical.txt)", "verified_date": "2026-08", "treatments": [ { "id": 771, "generic": "Omeprazole", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 20.0, "adult_dose": "20 mg once daily before a meal", "adult_duration": "4-8 weeks", "dose_source": "Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (omeprazole monograph)", "rationale": "PPI therapy is first-line for NSAID-induced and reactive gastritis; if H. pylori positive, eradicate it.", "cautions": [ "For NSAID-induced gastritis, stop the offending NSAID.", "For H. pylori-associated gastritis, cross-refer to the H. pylori eradication regimen.", "Distinguish from functional dyspepsia (gastritis implies mucosal inflammation visible on endoscopy)." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Specialist pediatric gastroenterology use only", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "OMEGASTAZOLE 20MG 14 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RIVA PHARMA S.A.E.", "price_egp": 18.0, "pack_count": 14, "unit_price": 1.29, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OMEPRAL 20MG 14 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 32.0, "pack_count": 14, "unit_price": 2.29, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "RISEK 20 MG 28 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JULPHAR", "price_egp": 75.0, "pack_count": 28, "unit_price": 2.68, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OMISEC 20MG 14CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "THE UNITED PHARMACEUTICALS CO LTD-JORDAN > MODERN PHARMA", "price_egp": 42.0, "pack_count": 14, "unit_price": 3.0, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "EPIRAZOLE 20MG 14CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 44.0, "pack_count": 14, "unit_price": 3.14, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OMEPAK 20 MG 14 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SEDICO", "price_egp": 50.0, "pack_count": 14, "unit_price": 3.57, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "RISEK 20 MG 14 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JULPHAR", "price_egp": 57.0, "pack_count": 14, "unit_price": 4.07, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NAPIZOLE 20MG 14 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS", "price_egp": 62.0, "pack_count": 14, "unit_price": 4.43, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "gastritis" }, { "id": 772, "generic": "Lansoprazole", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 30.0, "adult_dose": "30 mg once daily in the morning at least 30 minutes before food; 15 mg once daily where the purpose is prophylaxis of NSAID-associated gastroduodenal injury in a patient over 65 or with a previous ulcer", "adult_duration": "4 weeks for symptom control, up to 8 weeks if gastric ulceration is present; up to 12 weeks for NSAID prophylaxis", "dose_source": "Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (lansoprazole monograph)", "rationale": "17 live products and the cheapest widely stocked alternative to omeprazole. The 15 mg NSAID-prophylaxis dose is the one most gastritis presentations in Egyptian primary care actually need, because NSAID use is the commonest identifiable cause.", "cautions": [ "Do not exceed 30 mg daily in the elderly unless there is a clear clinical reason - clearance is reduced.", "15 mg daily in severe hepatic impairment (Child-Pugh C)", "Stop and reconsider if severe or persistent diarrhoea develops - colitis and Clostridioides difficile are reported.", "Long-term use is associated with hypomagnesaemia, vitamin B12 deficiency, fundic gland polyps and fracture risk.", "Stop for any rash on sun-exposed skin with joint pain - subacute cutaneous lupus erythematosus is a recognised PPI reaction.", "Orodispersible tablets must not be crushed or chewed." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Avoid under 1 year. Children 11 years and under: 15 mg once daily if 30 kg or less, 30 mg once daily if over 30 kg. Children 12 years and over: 15 mg once daily.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "1 to 11 years", "age_min_months": 12, "age_max_months": 143, "dose_text": "15 mg once daily at 30 kg or less; 30 mg once daily over 30 kg. Avoid under 1 year." }, { "label": "12 years and over", "age_min_months": 144, "age_max_months": 216, "dose_text": "15 mg once daily" } ], "peds_doses": null, "brands": [ { "trade_name": "LORAL 30MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 30.0, "pack_count": 10, "unit_price": 3.0, "strength_mg": 30.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "GASTROCURE 30MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALFACURE PHARMACEUTICALS", "price_egp": 33.6, "pack_count": 10, "unit_price": 3.36, "strength_mg": 30.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ZOLLIPAK 30MG 10 CAPS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SEDICO", "price_egp": 33.6, "pack_count": 10, "unit_price": 3.36, "strength_mg": 30.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LOPRAL 30MG 5 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UP PHARMA", "price_egp": 27.5, "pack_count": 5, "unit_price": 5.5, "strength_mg": 30.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LANTANON 30MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UNIPHARMA CO. > UNIPHARMA", "price_egp": 57.0, "pack_count": 10, "unit_price": 5.7, "strength_mg": 30.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ZALLANZ 30 MG 20 DELAYED REL. CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL-OBOUR", "price_egp": 60.0, "pack_count": null, "unit_price": null, "strength_mg": 30.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ZALLANZ 30 MG 30 DELAYED REL. CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL-OBOUR", "price_egp": 90.0, "pack_count": null, "unit_price": null, "strength_mg": 30.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LANSOFAST 30 MG 30 ORO-DISPERSIBLE TABS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "NAPCO > DELPHI PHARMA", "price_egp": 174.0, "pack_count": null, "unit_price": null, "strength_mg": 30.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "gastritis" }, { "id": 774, "generic": "Referral & safety-netting (no drug therapy)", "line": 1, "is_adjunct": false, "form": null, "strength_mg": null, "adult_dose": null, "adult_duration": null, "dose_source": "Gastritis - disease-level clinical article (gastritis-clinical.txt)", "rationale": "Carries the referral criteria and warning signs for this condition, which apply whichever treatment is chosen.", "cautions": [ "RED FLAG - Alarm signs (weight loss, bleeding, dysphagia, abdominal mass, persistent vomiting, family history of UGI cancer) require urgent investigation or endoscopy." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": null, "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [], "condition_id": "gastritis" }, { "id": 773, "generic": "Rabeprazole", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": 20.0, "adult_dose": "20 mg once daily in the morning; 10 mg once daily is adequate for maintenance in many patients", "adult_duration": "4-8 weeks, then step down to 10 mg daily or stop", "dose_source": "Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (rabeprazole monograph)", "rationale": "18 live products. Needs no dose reduction in renal impairment and only a modest one in severe liver disease, which makes it a practical PPI in a comorbid patient.", "cautions": [ "The formulary states rabeprazole is contraindicated in pregnancy and not recommended in breastfeeding - use omeprazole instead in a pregnant patient.", "Severe hepatic impairment (Child-Pugh C): use 10 mg with caution.", "Monitor magnesium at baseline and periodically if the patient is also on digoxin or a diuretic.", "No dose change is needed in renal impairment.", "Long-term PPI cautions apply: Clostridioides difficile, B12 deficiency, fracture risk." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Not recommended in children - the formulary states there are insufficient safety and efficacy data at any paediatric age.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "RABEGERDAZOLE 20 MG 21 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AL ROWAD PHARMACEUTICAL INDUSTRIAL CO.", "price_egp": 40.5, "pack_count": 21, "unit_price": 1.93, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "RABEPRAZOLE 20 MG 14 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS > SANOFI", "price_egp": 31.2, "pack_count": 14, "unit_price": 2.23, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PACREDO 20 MG 30 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MARCYRL PHARMACEUTICAL INDUSTRIES (MPI) > SPLENDID PHARMA", "price_egp": 121.5, "pack_count": 30, "unit_price": 4.05, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BEPRA 20MG 21 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS", "price_egp": 154.5, "pack_count": 21, "unit_price": 7.36, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "IDIZOLE 20MG 7 ENTERIC COATED TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 19.2, "pack_count": null, "unit_price": null, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "HYGIGASTIN 20 MG 14 ENTERIC COATED TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEDIZEN PHARMACEUTICAL INDUSTRIES > HYGINT PHARMACEUTICALS-EGYPT", "price_egp": 22.0, "pack_count": null, "unit_price": null, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "RABGERD 20 MG 14 E.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EGPI > TRUE INTERNATIONAL PHARMA", "price_egp": 70.0, "pack_count": null, "unit_price": null, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PATRIMAC 20 MG 28 E.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALROWAD FOR PHARMACEUTICAL INDUSTRIES > AI AIN PHARAM", "price_egp": 166.0, "pack_count": null, "unit_price": null, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "gastritis" } ] }