{
  "schema_version": 1,
  "kind": "condition",
  "id": "glossitis-atrophic",
  "name": "Atrophic glossitis & burning mouth syndrome",
  "category": "chronic",
  "sources": "Egyptian National Drug Formulary - Blood Disorder Medications 2025 · Egyptian National Drug Formulary - Nervous System 2025 (clonazepam monograph)",
  "review_status": "reviewed",
  "verified_against": "Egyptian National Drug Formulary - Blood Disorder Medications 2025 · Egyptian National Drug Formulary - Nervous System 2025 (clonazepam monograph)",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 807,
      "generic": "Multivitamin",
      "line": 1,
      "is_adjunct": false,
      "form": "oral.solid",
      "strength_mg": null,
      "adult_dose": "Take 1 B-complex + Iron + Folic acid tablet daily with meals",
      "adult_duration": "1-3 months",
      "dose_source": "Egyptian National Drug Formulary - Blood Disorder Medications 2025",
      "rationale": "Primary treatment targets nutritional deficiencies (iron, B12, folate, riboflavin) causing papillary atrophy",
      "cautions": [
        "Perform full blood count, serum ferritin, vitamin B12, and folate levels to identify exact hematatinic deficiency.",
        "Dark stools may occur due to iron content."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Child: age-appropriate pediatric multivitamin drops/syrup daily",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "LIMITLESS PRENATAL ORIGINAL 30 TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EVA PHARMA",
          "price_egp": 190.0,
          "pack_count": 30,
          "unit_price": 6.33,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "ZSWEV MAMA CARE 30 CAPSULES",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "DAWA EGYPT > ADVENT PHARMA",
          "price_egp": 220.0,
          "pack_count": 30,
          "unit_price": 7.33,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "LIMITLESS PRENATAL MAX 30 TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EVA PHARMA",
          "price_egp": 230.0,
          "pack_count": 30,
          "unit_price": 7.67,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "THYROGREEN 30 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "COPAD > NEW BOSTON PHARMACEUTICALS",
          "price_egp": 330.0,
          "pack_count": 30,
          "unit_price": 11.0,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "BIOVITA KIDS 60 GUMMIES",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "NUTRIXIA > INFINITY PHARM",
          "price_egp": 250.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "PHAROTITA SYRUP 120 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "ORGANICS > PHARO FOR SUPPLEMENTS",
          "price_egp": 220.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "glossitis-atrophic"
    },
    {
      "id": 808,
      "generic": "Clonazepam",
      "line": 2,
      "is_adjunct": false,
      "form": "oral.solid",
      "strength_mg": 0.5,
      "adult_dose": "0.25-0.5 mg tablet held in mouth/sucked without swallowing for 3 minutes then expectorated (or low oral dose 0.25 mg at bedtime)",
      "adult_duration": "2-4 weeks",
      "dose_source": "Egyptian National Drug Formulary - Nervous System 2025 (clonazepam monograph)",
      "rationale": "Topical or low-dose oral neuropathic agent for primary dysesthetic burning mouth syndrome when nutritional screen is negative",
      "cautions": [
        "Clonazepam is a benzodiazepine: sedation, cognitive impairment, and physical dependence are risks.",
        "Avoid alcohol and driving.",
        "The formulary doses clonazepam systemically for seizures and panic. Sucking a tablet for local effect in burning mouth syndrome is an off-label use of the tablet and is not a dose the formulary gives."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Not indicated in children",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "RONATRIL 0.5MG 10 TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "HI-PHARM",
          "price_egp": 1.75,
          "pack_count": 10,
          "unit_price": 0.17,
          "strength_mg": 0.5,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "SIGOTRYL 0.5MG 10 TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "SIGMA",
          "price_egp": 1.75,
          "pack_count": 10,
          "unit_price": 0.17,
          "strength_mg": 0.5,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "AMOTRIL 0.5 MG 30 TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "AMOUN",
          "price_egp": 16.5,
          "pack_count": 30,
          "unit_price": 0.55,
          "strength_mg": 0.5,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "APETRYL 0.5 MG 50 TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MULTI-APEX",
          "price_egp": 45.0,
          "pack_count": 50,
          "unit_price": 0.9,
          "strength_mg": 0.5,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "KLOZEPAM 0.5MG 20 TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "SIGMA",
          "price_egp": 24.0,
          "pack_count": 20,
          "unit_price": 1.2,
          "strength_mg": 0.5,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "KLOZEPAM 2.5MG/ML 15ML ORAL DROPS",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "SIGMA",
          "price_egp": 40.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 2.5,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "RIVOTRIL 2.5MG/ML ORAL DROPS 10ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "F.HOFFMAN LA ROCHE > EGYPTIAN PHARMACEUTICAL TRADING COMPANY",
          "price_egp": 87.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 2.5,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "glossitis-atrophic"
    }
  ]
}