{
  "schema_version": 1,
  "kind": "condition",
  "id": "head-lice",
  "name": "Head Lice (pediculosis capitis)",
  "category": "infectious",
  "sources": "AAP Clinical Report: Head Lice 2022 for the indication, with the product from Egyptian National Drug Formulary - Antimicrobial 2023, Permethrin monograph (printed page 414): \"Head lice: Topical: Cream rinse/lotion 1%: Prior to application, wash hair with conditioner-free shampoo; rinse with water and towel dry. Apply a sufficient amount of lotion or cream rinse to saturate the hair and scalp ... Leave on hair for 10 minutes (but no longer), then rinse off with warm water; remove remaining nits with a nit comb. A single application is generally sufficient; however, may repeat 7 days after first treatment if lice or nits are still present.\" The formulary's head lice strength is 1% against the 2.5% given here, and it puts 5% at scabies. · AAP Clinical Report: Head Lice 2022 · CDC Parasites: Lice: Head Lice Treatment 2020 · Ovide (malathion) Lotion 0.5% US prescribing information (DailyMed, Taro)",
  "review_status": "reviewed",
  "verified_against": "AAP Clinical Report: Head Lice 2022 for the indication, with the product from Egyptian National Drug Formulary - Antimicrobial 2023, Permethrin monograph (printed page 414): \"Head lice: Topical: Cream rinse/lotion 1%: Prior to application, wash hair with conditioner-free shampoo; rinse with water and towel dry. Apply a sufficient amount of lotion or cream rinse to saturate the hair and scalp ... Leave on hair for 10 minutes (but no longer), then rinse off with warm water; remove remaining nits with a nit comb. A single application is generally sufficient; however, may repeat 7 days after first treatment if lice or nits are still present.\" The formulary's head lice strength is 1% against the 2.5% given here, and it puts 5% at scabies. · AAP Clinical Report: Head Lice 2022 · Ovide (malathion) Lotion 0.5% US prescribing information (DailyMed, Taro)",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 855,
      "generic": "Permethrin",
      "line": 1,
      "is_adjunct": false,
      "form": "topical",
      "strength_mg": null,
      "adult_dose": "Apply 2.5% lotion or cream to clean, towel-dried hair and scalp, leave on for 10 minutes, then rinse thoroughly with warm water. Repeat application in 7-10 days.",
      "adult_duration": "2 applications 7-10 days apart",
      "dose_source": "AAP Clinical Report: Head Lice 2022 for the indication, with the product from Egyptian National Drug Formulary - Antimicrobial 2023, Permethrin monograph (printed page 414): \"Head lice: Topical: Cream rinse/lotion 1%: Prior to application, wash hair with conditioner-free shampoo; rinse with water and towel dry. Apply a sufficient amount of lotion or cream rinse to saturate the hair and scalp ... Leave on hair for 10 minutes (but no longer), then rinse off with warm water; remove remaining nits with a nit comb. A single application is generally sufficient; however, may repeat 7 days after first treatment if lice or nits are still present.\" The formulary's head lice strength is 1% against the 2.5% given here, and it puts 5% at scabies.",
      "rationale": "AAP/CDC guidelines specify 1% permethrin baseline; Ectomethrin 2.5% lotion/cream is the registered formulation available in Egyptian retail pharmacies.",
      "cautions": [
        "Avoid contact with eyes and mucous membranes; rinse thoroughly with water if contact occurs.",
        "Re-treatment on day 7-10 is essential to kill newly hatched nits, as topical pediculicides are not completely ovicidal.",
        "Examine and treat all household members with active infestation simultaneously to prevent re-infestation."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Suitable for infants and children >=2 months old. Apply to scalp/hair, leave on for 10 minutes, rinse. Repeat in 7-10 days.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "ECTOMETHRIN 2.5 % CREAM 20 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MISR > APC (ARAB PERFUMES  CHEMICALS AND PHARMACEUTICAL CO.)",
          "price_egp": 12.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 20000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "ECTOMETHRIN 5 % CREAM. 20 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MISR > APC (ARAB PERFUMES  CHEMICALS AND PHARMACEUTICAL CO.)",
          "price_egp": 21.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 20000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "ECTOMETHRIN 5% OINT. 20 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MISR > APC (ARAB PERFUMES  CHEMICALS AND PHARMACEUTICAL CO.)",
          "price_egp": 21.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 20000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "NEWCID 1% 60ML SHAMPOO",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "CID",
          "price_egp": 9.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "NEWCID 1% 80ML SHAMPOO",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "CID",
          "price_egp": 11.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "head-lice"
    },
    {
      "id": 856,
      "generic": "Malathion",
      "line": 2,
      "is_adjunct": false,
      "form": "topical",
      "strength_mg": null,
      "adult_dose": "Apply 0.5% lotion to dry hair and scalp, allow to air dry naturally, leave on for 8-12 hours (or overnight), then wash out with shampoo. Repeat in 7-9 days if live lice persist.",
      "adult_duration": "1-2 applications 7-9 days apart",
      "dose_source": "Ovide (malathion) Lotion 0.5% US prescribing information (DailyMed, Taro)",
      "rationale": "Second-line organophosphate pediculicide registered in Egypt (Prioderm / Lice Clean 0.5% lotion) used when permethrin treatment failure or resistance occurs",
      "cautions": [
        "Flammable due to isopropyl alcohol base; keep away from open flames, heat sources, and electric hair dryers while applied.",
        "Do not use in infants under 6 months of age without specialist advice.",
        "May cause temporary scalp irritation or stinging.",
        "Leave the hair uncovered while it dries, and comb it through with a fine nit comb after rinsing - the lotion kills, the comb removes.",
        "It is an organophosphate. If a child swallows any, that is an immediate hospital trip, not a wait."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Approved for children >=6 months (BNFC 2024) or >=6 years (CDC 2020 / FDA). Apply to dry hair, leave for 8-12 hours, then shampoo out. Repeat in 7-9 days.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "PRIODERM  0.5 % LOTION 60 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "PHARCO > MUNDIPHARMA",
          "price_egp": 8.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "LICE CLEAN 0.5GM/100ML TOPICAL LOTION",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "WESTERN PHARMACEUTICALS INDUSTRIES > WESTERN PHARMA",
          "price_egp": 8.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "head-lice"
    }
  ]
}