OMEPRAZOLE
Strength20 mg
Formoral.solid
20 mg once daily in the morning before food x 8 weeks, then reassess
Licensed in children over 1 year at 10-20 mg daily under specialist care. A hiatus hernia found in a child is a paediatric surgical question, not a prescription.
Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (omeprazole monograph): "Gastroesophageal reflux disease, including reflux esophagitis - Oral: 10-20 mg once daily. Up to 40 mg once daily in refractory cases. Duration: 4-8 weeks." The paediatric statement shown here is not from this formulary, whose only paediatric omeprazole line is 0.7-1.4 mg/kg in children over 2 years for severe ulcerating esophagitis. The ACG GERD guideline is not held in this corpus.
Most hiatus hernias are asymptomatic and need nothing. When they cause reflux symptoms the treatment is the reflux treatment: the article's recommendation is a proton pump inhibitor once a day, taken in the morning before food, over a course of 8 weeks. The dose is the sourced omeprazole dose for reflux.
- MOST ARE ASYMPTOMATIC AND NEED NO TREATMENT. StatPearls: 55-60% of people over 50 have one, and symptoms appear in about 10% of them at most. Finding one on a scan is not a reason to start a drug.
- Dysphagia, vomiting, weight loss, anaemia or chest pain are not to be treated with a PPI and reviewed in two months - they need endoscopy.
- A large paraesophageal (type II-IV) hernia can strangulate. Sudden severe chest or epigastric pain with retching and inability to vomit is a surgical emergency.
- Surgery is for a mechanically defective sphincter, failure of PPI, severe erosive oesophagitis, or a symptomatic large paraesophageal hernia - not for the hernia's existence.
- Long-term PPI is not free of cost: review the need at every repeat rather than continuing it by default.
| Egyptian brand | Manufacturer | Indicative price |
|---|---|---|
| OMEGASTAZOLE 20MG 14 CAPS. | RIVA PHARMA S.A.E. | 18.00 EGP (1.29/unit) |
| OMEPRAL 20MG 14 CAPS. | MEMPHIS | 32.00 EGP (2.29/unit) |
| RISEK 20 MG 28 CAPS. | JULPHAR | 75.00 EGP (2.68/unit) |
| OMISEC 20MG 14CAPS. | THE UNITED PHARMACEUTICALS CO LTD-JORDAN > MODERN PHARMA | 42.00 EGP (3.00/unit) |
| EPIRAZOLE 20MG 14CAPS. | EIPICO | 44.00 EGP (3.14/unit) |
| OMEPAK 20 MG 14 CAPS. | SEDICO | 50.00 EGP (3.57/unit) |
| RISEK 20 MG 14 CAPS. | JULPHAR | 57.00 EGP (4.07/unit) |
| NAPIZOLE 20MG 14 CAPS. | GLOBAL NAPI PHARMACEUTICALS | 62.00 EGP (4.43/unit) |