{ "schema_version": 1, "kind": "condition", "id": "impetigo", "name": "Impetigo (localized and systemic)", "category": "infectious", "sources": "Impetigo - StatPearls - NCBI Bookshelf (NBK430974) - disease-level clinical article (impetigo-full.txt) · Egyptian Drug Authority - National Guidance of Rational Antimicrobial Use in the Management of Skin and Soft Tissue Infection, EDREX:GU.CAP.Care.015 version 1, 11/2025 · Egyptian National Drug Formulary - antimicrobial-2023.pdf, Clindamycin monograph (chapter PDF p287) · Egyptian National Drug Formulary - Antimicrobial 2023 (doxycycline monograph) · Egyptian National Drug Formulary - Antimicrobial 2023, sulfamethoxazole and trimethoprim monograph · Egyptian National Drug Formulary - Antimicrobial 2023 (cefadroxil monograph) · Fucidin 20 mg/g Cream (fusidic acid) SmPC sections 4.1 and 4.2 (eMC product 5510) · Mupirocin ointment USP 2% US prescribing information (DailyMed SetID b8e115ce-c8ff-4d08-b865-71dc4d0e51a1)", "review_status": "reviewed", "verified_against": "Impetigo - StatPearls - NCBI Bookshelf (NBK430974) - disease-level clinical article (impetigo-full.txt) · Egyptian Drug Authority - National Guidance of Rational Antimicrobial Use in the Management of Skin and Soft Tissue Infection, EDREX:GU.CAP.Care.015 version 1, 11/2025 · Egyptian National Drug Formulary - antimicrobial-2023.pdf, Clindamycin monograph (chapter PDF p287) · Egyptian National Drug Formulary - Antimicrobial 2023 (doxycycline monograph) · Egyptian National Drug Formulary - Antimicrobial 2023, sulfamethoxazole and trimethoprim monograph · Egyptian National Drug Formulary - Antimicrobial 2023 (cefadroxil monograph) · Fucidin 20 mg/g Cream (fusidic acid) SmPC sections 4.1 and 4.2 (eMC product 5510) · Mupirocin ointment USP 2% US prescribing information (DailyMed SetID b8e115ce-c8ff-4d08-b865-71dc4d0e51a1)", "verified_date": "2026-08", "treatments": [ { "id": 961, "generic": "Fusidic acid", "line": 1, "is_adjunct": false, "form": "topical", "strength_mg": null, "adult_dose": "Apply 2% cream or ointment TID to affected lesions", "adult_duration": "5 days", "dose_source": "Fucidin 20 mg/g Cream (fusidic acid) SmPC sections 4.1 and 4.2 (eMC product 5510): \"Fucidin 20 mg/g cream is indicated either alone or in combination with systemic therapy, in the treatment of primary and secondary skin infections caused by sensitive strains of Staphylococcus aureus, Streptococcus spp and Corynebacterium minutissimum.\" and \"Uncovered lesions - apply gently three or four times daily.\" The 5-day course sits inside that frequency; the SmPC states no duration.", "rationale": "First-line topical treatment for localized non-bullous impetigo", "cautions": [ "Limit treatment to 5-7 days to prevent bacterial resistance.", "Avoid application near the eyes.", "Wash hands before and after application." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Apply 2% cream or ointment TID to affected lesions for 5 days", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "FOSTINO 2% TOPICAL GEL 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ZAD", "price_egp": 8.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ANESTY 2% TOPICAL GEL 15GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MARCYRL PHARMACEUTICAL INDUSTRIES (MPI)", "price_egp": 8.5, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FUSIDIC ACID 2% GEL 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA", "price_egp": 8.5, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FUSIDICTAM 2 % TOP. CREAM 30 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEDIZEN PHARMACEUTICAL INDUSTRIES > MAGIC PHARMA-EGYPT", "price_egp": 26.5, "pack_count": null, "unit_price": null, "strength_mg": 30000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FUCI-TOP 2% CREAM 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "HIKMA PHARMA", "price_egp": 44.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FUCIDIN 2% CREAM 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MINA PHARM > LEO PHARMACEUTICAL PRODUCTS", "price_egp": 56.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FUCIDIN 2% CREAM 30 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MINA PHARM > LEO PHARMACEUTICAL PRODUCTS", "price_egp": 96.0, "pack_count": null, "unit_price": null, "strength_mg": 30000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FUCIDIN 2% OINTMENT 30 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MINA PHARM > LEO PHARMACEUTICAL PRODUCTS", "price_egp": 96.0, "pack_count": null, "unit_price": null, "strength_mg": 30000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "impetigo" }, { "id": 962, "generic": "Mupirocin", "line": 1, "is_adjunct": false, "form": "topical", "strength_mg": null, "adult_dose": "Apply 2% ointment TID to affected skin area", "adult_duration": "5 days", "dose_source": "Mupirocin ointment USP 2% US prescribing information, INDICATIONS AND USAGE and DOSAGE AND ADMINISTRATION (DailyMed SetID b8e115ce-c8ff-4d08-b865-71dc4d0e51a1): \"Mupirocin ointment is indicated for the topical treatment of impetigo due to susceptible isolates of Staphylococcus aureus and Streptococcus pyogenes.\" and \"Apply a small amount of mupirocin ointment, with a cotton swab or gauze pad, to the affected area 3 times daily for up to 10 days.\" The 5-day course sits inside the label's 10-day ceiling.", "rationale": "Alternative topical treatment when fusidic acid resistance is suspected", "cautions": [ "Do not use in nasal passages unless using specific nasal formulation.", "Avoid prolonged use (>7 days) to reduce risk of resistance.", "Local skin reactions (burning, stinging) may occur." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Apply 3 times a day for 5 days. Licenses for mupirocin use in infants vary between products; check individual SPCs.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "BACTROFORM 2% TOP. OINT. 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "WESTERN PHARMACEUTICALS INDUSTRIES > WESTERN PHARMA", "price_egp": 35.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MUPIROCIN SAJA 2% TOP. OINT. 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "BIOPHARM EGYPT > SAJA PHARMA", "price_egp": 35.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MUPIRAX 2% OINT. 10 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS", "price_egp": 48.0, "pack_count": null, "unit_price": null, "strength_mg": 10000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MUPIROCIN SAJA 2% TOP. OINT. 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "BIOPHARM EGYPT > SAJA PHARMA", "price_egp": 83.0, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MUPIRAX 2% OINT. 30 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS", "price_egp": 118.0, "pack_count": null, "unit_price": null, "strength_mg": 30000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "impetigo" }, { "id": 963, "generic": "Cefadroxil", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": 500.0, "adult_dose": "500 mg BID for widespread or severe impetigo", "adult_duration": null, "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023 (cefadroxil monograph)", "rationale": "Oral antibiotic for widespread or complicated impetigo", "cautions": [ "Reserve oral antibiotics for widespread, recurrent, or systemic disease.", "Caution in penicillin allergy.", "Gastrointestinal upset may occur." ], "peds_mgkg_low": 30.0, "peds_mgkg_high": 30.0, "peds_max_mg": 1000.0, "peds_basis": "day", "peds_unit": "mg", "peds_note": "30 mg/kg/day in 2 divided doses for widespread impetigo", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 300, "high_mg": 300, "capped": false }, { "weight_kg": 20, "low_mg": 600, "high_mg": 600, "capped": false }, { "weight_kg": 30, "low_mg": 900, "high_mg": 900, "capped": false }, { "weight_kg": 40, "low_mg": 1000, "high_mg": 1000, "capped": true } ], "brands": [ { "trade_name": "MEGADROXIL 500 MG 8 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SHIFA MEDICAL PRODUCTS > MASH PREMIERE", "price_egp": 4.5, "pack_count": 8, "unit_price": 0.56, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CEFADROXIL 500MG 8 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA", "price_egp": 7.5, "pack_count": 8, "unit_price": 0.94, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DURABIOTIC 500MG 8 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "LOGESTIC PHARMA FOR PHARMACEUTICALS", "price_egp": 9.0, "pack_count": 8, "unit_price": 1.12, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BIODROXIL 500MG 8 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA > NOVARTIS", "price_egp": 10.5, "pack_count": 8, "unit_price": 1.31, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LONGICEF 500 MG 8 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 15.0, "pack_count": 8, "unit_price": 1.88, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CURISAFE 500MG 8 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO B", "price_egp": 45.0, "pack_count": 8, "unit_price": 5.62, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DURICEF 500MG 12 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SMITHKLINE BEECHAM", "price_egp": 72.0, "pack_count": 12, "unit_price": 6.0, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LONGICEF 125MG/5ML SUSP. 60 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 4.25, "pack_count": null, "unit_price": null, "strength_mg": 125.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "CEFADROXIL 250MG/5ML PD. FOR ORAL SUSP. 60ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA", "price_egp": 7.5, "pack_count": null, "unit_price": null, "strength_mg": 250.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "impetigo" }, { "id": 964, "generic": "Clindamycin", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": 300.0, "adult_dose": "150 to 300 mg every 6 hours by mouth, rising to 300 to 450 mg every 6 hours in more severe disease", "adult_duration": "7 days", "dose_source": "Egyptian Drug Authority - National Guidance of Rational Antimicrobial Use in the Management of Skin and Soft Tissue Infection, EDREX:GU.CAP.Care.015 version 1, 11/2025 - verbatim, on impetigo: \"When MRSA is suspected or confirmed: One of the following: Doxycycline. SMX-TMP. Clindamycin\", with the course length \"Oral therapy for ecthyma or impetigo should be a7-day.\" and the adult dose \"300-400 mg 4 times per day po.\" / \"MRSA: 600-900 mg every 8 h IV or 300 mg 4 times daily or 450 mg 3 times.\" | Egyptian National Drug Formulary - antimicrobial-2023.pdf, Clindamycin monograph (chapter PDF p287) - verbatim, for the indication and the paediatric dose: \"Skin and soft tissue infection: Treatment of skin and soft tissue infection\" and \"Oral: Infants, Children, and Adolescents: Hydrochloride salt (capsule): 8 to 20 mg/kg/day divided every 6 to 8 hours.\"", "rationale": "Covers methicillin-resistant Staphylococcus aureus and Streptococcus pyogenes in one drug, which matters in impetigo because streptococcus causes a large share of it.", "cautions": [ "Watch the bowels. Clindamycin carries the clearest Clostridioides difficile risk of the three options here - the formulary lists antibiotic-associated colitis and pseudomembranous colitis, and asks prescribers to observe for changes in bowel frequency.", "New or worsening diarrhoea during or after the course is a reason to stop and reassess, not to wait it out.", "Not in infants under one month.", "The 1% topical solution and gel sold in Egypt are acne preparations and are a different treatment from this one - the oral capsule is what this dose refers to." ], "peds_mgkg_low": 8.0, "peds_mgkg_high": 20.0, "peds_max_mg": null, "peds_basis": "day", "peds_unit": "mg", "peds_note": "8 to 20 mg/kg/day by mouth, divided every 6 to 8 hours, using the capsule (hydrochloride) salt. Not for infants under one month.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 80, "high_mg": 200, "capped": false }, { "weight_kg": 20, "low_mg": 160, "high_mg": 400, "capped": false }, { "weight_kg": 30, "low_mg": 240, "high_mg": 600, "capped": false }, { "weight_kg": 40, "low_mg": 320, "high_mg": 800, "capped": false } ], "brands": [ { "trade_name": "ADCOCLINDACE 300 MG 16 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 24.0, "pack_count": 16, "unit_price": 1.5, "strength_mg": 300.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CLINACYN 300MG 16 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA > EGYPTIAN PHARMACISTS COMPANY", "price_egp": 31.5, "pack_count": 16, "unit_price": 1.97, "strength_mg": 300.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CLINDAM 300 MG 16 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA > OCTOBER PHARMA", "price_egp": 75.0, "pack_count": 16, "unit_price": 4.69, "strength_mg": 300.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MEPACLIND 300MG 8 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEPACO", "price_egp": 38.0, "pack_count": 8, "unit_price": 4.75, "strength_mg": 300.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CLINDACINE ART 300 MG 12 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA > ART PHARMA", "price_egp": 76.0, "pack_count": 12, "unit_price": 6.33, "strength_mg": 300.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ALFACLINDAMYCIN 300 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ATCO PHARMA > ROTABIOGEN", "price_egp": 69.0, "pack_count": 10, "unit_price": 6.9, "strength_mg": 300.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DALACIN C 300MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PFIZER", "price_egp": 114.0, "pack_count": 10, "unit_price": 11.4, "strength_mg": 300.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "KLENDABIOTICAM 1 % TOP. SOLUTION", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PANAX PHARMA", "price_egp": 8.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "ADCOCLINDACE 10MG/ML TOP. SOL.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 12.0, "pack_count": null, "unit_price": null, "strength_mg": 10.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "impetigo" }, { "id": 965, "generic": "Doxycycline", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": 100.0, "adult_dose": "100 mg twice daily by mouth", "adult_duration": "7 days", "dose_source": "Egyptian Drug Authority - National Guidance of Rational Antimicrobial Use in the Management of Skin and Soft Tissue Infection, EDREX:GU.CAP.Care.015 version 1, 11/2025 - verbatim, on impetigo: \"When MRSA is suspected or confirmed: One of the following: Doxycycline.\", with the course length \"Oral therapy for ecthyma or impetigo should be a7-day.\" and the adult dose \"100 mg orally or IV 2 times per day.\" | Egyptian National Drug Formulary - Antimicrobial 2023 (doxycycline monograph) - verbatim, for the paediatric dose: \"Children and Adolescents: Oral, IV: 2.2 mg/kg/dose every 12 hours, maximum dose: 100 mg/dose.\"", "rationale": "An MRSA-active oral option that is stocked everywhere in Egypt and costs a few pounds a course.", "cautions": [ "Under 8 years, the formulary reserves doxycycline for severe, potentially life-threatening infection or where there is no better alternative. Impetigo in a young child is neither, so clindamycin is the option to use instead.", "The formulary itself does not rate doxycycline as the preferred drug for any staphylococcal infection - it is included here because it is active against MRSA, not because it is the best anti-staphylococcal option.", "Avoid in the second and third trimesters of pregnancy and while breastfeeding." ], "peds_mgkg_low": 2.2, "peds_mgkg_high": 2.2, "peds_max_mg": 100.0, "peds_basis": "dose", "peds_unit": "mg", "peds_note": "2.2 mg/kg per dose every 12 hours, never above 100 mg in a dose - but see the age restriction in the cautions before using this in a child.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 22, "high_mg": 22, "capped": false }, { "weight_kg": 20, "low_mg": 44, "high_mg": 44, "capped": false }, { "weight_kg": 30, "low_mg": 66, "high_mg": 66, "capped": false }, { "weight_kg": 40, "low_mg": 88, "high_mg": 88, "capped": false } ], "brands": [ { "trade_name": "FARCODOXIN 100MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 11.0, "pack_count": 10, "unit_price": 1.1, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DOXY M.R.100 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ADWIA", "price_egp": 12.0, "pack_count": 10, "unit_price": 1.2, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "GRANUDOXY 100MG 10 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS > PIERRE FRANCE", "price_egp": 12.0, "pack_count": 10, "unit_price": 1.2, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DOXYDOX 100 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 23.0, "pack_count": 10, "unit_price": 2.3, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DOXYMYCIN 100 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL NILE.", "price_egp": 30.0, "pack_count": 10, "unit_price": 3.0, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TABOCINE 100MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "TABUK PHARMACEUTICAL MANUFACTURING COMPANY > TABUK PHARMA", "price_egp": 46.0, "pack_count": 10, "unit_price": 4.6, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VIBRAMYCIN 100MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PFIZER", "price_egp": 65.0, "pack_count": 10, "unit_price": 6.5, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "impetigo" }, { "id": 966, "generic": "Sulphamethoxazole + Trimethoprim", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": null, "adult_dose": "1 to 2 double-strength tablets (800 mg sulphamethoxazole with 160 mg trimethoprim) twice daily", "adult_duration": "7 days", "dose_source": "Egyptian Drug Authority - National Guidance of Rational Antimicrobial Use in the Management of Skin and Soft Tissue Infection, EDREX:GU.CAP.Care.015 version 1, 11/2025 - verbatim, on impetigo: \"When MRSA is suspected or confirmed: One of the following: ... SMX-TMP.\", with the course length \"Oral therapy for ecthyma or impetigo should be a7-day.\" and the adult dose \"1 or 2 double-strength tablets 2 times per day.\" | Egyptian National Drug Formulary - Antimicrobial 2023, sulfamethoxazole and trimethoprim monograph - verbatim, for the paediatric dose: \"General dosing, susceptible infection: Infants >=2 months, Children, and Adolescents: Oral, IV: 6 to 12 mg TMP/kg/day in divided doses every 12 hours; maximum single dose: 160 mg TMP/dose\"", "rationale": "MRSA-active, widely stocked and cheap - but the narrowest of the three options here, because it cannot be relied on against streptococcus.", "cautions": [ "Use only where group A streptococcus is not the cause, or together with a drug that covers streptococcus. The disease article is explicit that co-trimoxazole is limited to cases where group A streptococci are ruled out, or given alongside an anti-streptococcal antibiotic. Streptococcus accounts for a large share of impetigo, so this is a real limit, not a footnote.", "Contraindicated under 2 months of age, and in pregnancy and breastfeeding.", "Causes haemolysis in G6PD deficiency, which is common enough in Egypt to ask about before prescribing.", "Contraindicated in a known sulfonamide allergy, in megaloblastic anaemia from folate deficiency, and in marked liver damage." ], "peds_mgkg_low": 6.0, "peds_mgkg_high": 12.0, "peds_max_mg": 320.0, "peds_basis": "day", "peds_unit": "mg", "peds_note": "6 to 12 mg/kg/day divided every 12 hours, counted on the TRIMETHOPRIM component alone, not on the combined tablet weight, to a ceiling of 160 mg of trimethoprim in a single dose. The 200/40 mg per 5 mL suspension carries 40 mg of trimethoprim in each 5 mL. Not under 2 months of age.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 60, "high_mg": 120, "capped": false }, { "weight_kg": 20, "low_mg": 120, "high_mg": 240, "capped": false }, { "weight_kg": 30, "low_mg": 180, "high_mg": 320, "capped": true }, { "weight_kg": 40, "low_mg": 240, "high_mg": 320, "capped": true } ], "brands": [ { "trade_name": "CO-TRIMOXAZOLE 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP", "price_egp": 5.0, "pack_count": 20, "unit_price": 0.25, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "COTRIL 400/80MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL NASR", "price_egp": 38.0, "pack_count": 20, "unit_price": 1.9, "strength_mg": 80.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SEPTAZOLE FORTE 800/160MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALEXANDRIA", "price_egp": 56.0, "pack_count": 20, "unit_price": 2.8, "strength_mg": 160.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SEPTRIN D.S 10 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE > ASPEN PHARMA TRADING LIMITED", "price_egp": 28.0, "pack_count": 10, "unit_price": 2.8, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SEPTAZOLE 400/80MG 20*10 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALEXANDRIA", "price_egp": 340.0, "pack_count": 10, "unit_price": 34.0, "strength_mg": 80.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SUTRIM 400/80MG 20*10 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 340.0, "pack_count": 10, "unit_price": 34.0, "strength_mg": 80.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CO-TRIMOXAZOLE 200/40MG SUSP. 120ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP", "price_egp": 6.0, "pack_count": null, "unit_price": null, "strength_mg": 40.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "SUTRIM 200/40MG SUSP. 100ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 18.5, "pack_count": null, "unit_price": null, "strength_mg": 40.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "impetigo" } ] }