{
  "schema_version": 1,
  "kind": "condition",
  "id": "infantile-colic",
  "name": "Infantile Colic",
  "category": "chronic",
  "sources": "NICE Clinical Knowledge Summaries Infantile Colic 2022 · Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (simethicone monograph)",
  "review_status": "reviewed",
  "verified_against": "Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (simethicone monograph) · Infantile Colic - disease-level clinical article (infantile-colic-clinical.txt)",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 969,
      "generic": "Simethicone",
      "line": 1,
      "is_adjunct": false,
      "form": "oral.liquid",
      "strength_mg": 40.0,
      "adult_dose": "Not applicable",
      "adult_duration": "not applicable",
      "dose_source": "Egyptian National Drug Formulary - Gastrointestinal Tract 2025 (simethicone monograph)",
      "rationale": "Pediatric condition presented in infant care.",
      "cautions": [
        "Exclude red flags: poor weight gain, vomiting, fever, or blood in stool.",
        "Defined by Rule of 3s: crying >3 hours/day, >3 days/week, >3 weeks in healthy infant.",
        "Reassure parents that condition is benign and self-limiting by 3-4 months."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Children: 100 to 200 mg orally 3 to 4 times daily or as required.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "BABY REST 40MG/0.6ML ORAL DROPS 15 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "PHARCO",
          "price_egp": 16.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 40.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "SIMETHICONE 2% (30ML) ORAL DROPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "AMRIYA",
          "price_egp": 24.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "SIMETHICONE-MUP 2% EMULSION ORAL DROPS 30 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MUP",
          "price_egp": 27.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "infantile-colic"
    },
    {
      "id": 970,
      "generic": "Referral & safety-netting (no drug therapy)",
      "line": 1,
      "is_adjunct": false,
      "form": null,
      "strength_mg": null,
      "adult_dose": null,
      "adult_duration": null,
      "dose_source": "Infantile Colic - disease-level clinical article (infantile-colic-clinical.txt)",
      "rationale": "Carries the referral criteria and warning signs for this condition, which apply whichever treatment is chosen.",
      "cautions": [
        "The red flags include fever requiring sepsis evaluation, abdominal distension, and onset outside the 3-4 month window."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": null,
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [],
      "condition_id": "infantile-colic"
    }
  ]
}