{
  "schema_version": 1,
  "kind": "condition",
  "id": "intertrigo",
  "name": "Intertrigo",
  "category": "infectious",
  "sources": "AAD Guidelines for Management of Superficial Cutaneous Infections 2020 · Intertrigo - StatPearls - NCBI Bookshelf (NBK531489) - disease-level clinical article (intertrigo-full.txt) · Egyptian National Drug Formulary - Antimicrobial 2023 (clotrimazole monograph) · Egyptian National Drug Formulary - Antimicrobial 2023, mupirocin monograph · Egyptian National Drug Formulary - Antimicrobial 2023, flucloxacillin monograph · Hydrocortisone Cream 1% w/w SmPC sections 4.1 and 4.2 (eMC product 13103) · No labelled dose - barrier preparation applied to intact skin, to effect",
  "review_status": "reviewed",
  "verified_against": "No labelled dose - barrier preparation applied to intact skin, to effect · Egyptian National Drug Formulary - Antimicrobial 2023 (clotrimazole monograph) · Intertrigo - StatPearls - NCBI Bookshelf (NBK531489) - disease-level clinical article (intertrigo-full.txt) · Egyptian National Drug Formulary - Antimicrobial 2023, mupirocin monograph · Egyptian National Drug Formulary - Antimicrobial 2023, flucloxacillin monograph · Hydrocortisone Cream 1% w/w SmPC sections 4.1 and 4.2 (eMC product 13103)",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 1007,
      "generic": "Zinc oxide",
      "line": 1,
      "is_adjunct": false,
      "form": "topical",
      "strength_mg": null,
      "adult_dose": "Apply protective barrier cream to clean dry skin folds twice daily",
      "adult_duration": "until skin fold irritation resolves",
      "dose_source": "No labelled dose - barrier preparation applied to intact skin, to effect",
      "rationale": "Barrier protectant that shields irritated skin-fold surfaces from the friction and trapped moisture that cause intertrigo in the first place, rather than treating an infection. Addresses the mechanical cause described in the cautions.",
      "cautions": [
        "Keep skin folds clean, dry, and exposed to air where possible.",
        "Friction and moisture in inframammary, inguinal, or axillary folds are primary causes.",
        "Place cotton or absorbent material between skin folds to reduce friction."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Apply to clean dry skin folds in children",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "NAPI-CARE  OINT.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "ARAB DRUG COMPANY (ADCO)",
          "price_egp": 2.35,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "PENTADIAPER 20% TOPICAL CREAM 30 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EVA PHARMA > PENTA PHARMA",
          "price_egp": 3.5,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 30000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "BABY RASH FREE 30% OINT.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "ALEXANDRIA > MILLENIUM PHARMA-EGYPT",
          "price_egp": 5.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "EVA BABY CARE CREAM 50 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EVA PHARMA",
          "price_egp": 9.75,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 50000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "BALMIX 10% CREAM 30 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "SIGMA",
          "price_egp": 14.4,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 30000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "NONOPENT CREAM 75 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "> PENTA PHARMA",
          "price_egp": 100.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 75000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "NINO SERENO CREAM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EL NILE > GMCKS",
          "price_egp": 120.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "intertrigo"
    },
    {
      "id": 1008,
      "generic": "Clotrimazole",
      "line": 2,
      "is_adjunct": false,
      "form": "topical",
      "strength_mg": null,
      "adult_dose": "Apply to affected area twice daily",
      "adult_duration": "2-4 weeks (continue 1 week after resolution)",
      "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023 (clotrimazole monograph)",
      "rationale": "Topical imidazole antifungal that disrupts the fungal cell membrane, used when intertrigo becomes secondarily infected with Candida (the fiery red rash with satellite pustules noted in the cautions).",
      "cautions": [
        "AVOID potent topical corticosteroid combination creams in occluded skin folds (causes rapid skin atrophy, striae, and worsens fungal proliferation; low-potency hydrocortisone 1% may be used short-term max 7 days only for severe inflammation).",
        "Indicated when secondary Candida infection develops (fiery red rash with satellite pustules).",
        "Ensure skin fold is thoroughly dried after bathing before applying cream; advise loose-fitting cotton clothing.",
        "Sirolimus: Clotrimazole (Topical) may increase the serum concentration of Sirolimus."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Children ≥2 years: Apply twice daily (morning and night) for 2 weeks.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "CANEMAZOLE 1% CREAM 20 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "UP PHARMA",
          "price_egp": 5.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 20000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "CANDISTAN 1% TOPICAL CREAM 15 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "KAHIRA > ARAB DRUG COMPANY (ADCO)",
          "price_egp": 7.25,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 15000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "DERMATIN 1% TOP. CREAM 14 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "PHARCO",
          "price_egp": 15.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 14000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "CANESTEN 1% CREAM 20 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MEMPHIS > BAYER HEALTHCARE",
          "price_egp": 29.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 20000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "LOCASTEN 1% CREAM 20 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "ALEXANDRIA",
          "price_egp": 29.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 20000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "CANDISTAN 1% TOPICAL CREAM 40 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "KAHIRA > ARAB DRUG COMPANY (ADCO)",
          "price_egp": 36.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 40000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "intertrigo"
    },
    {
      "id": 1009,
      "generic": "Mupirocin",
      "line": 2,
      "is_adjunct": false,
      "form": "topical",
      "strength_mg": null,
      "adult_dose": "Apply 2% ointment to the affected fold twice daily",
      "adult_duration": "Until the rash resolves",
      "dose_source": "Intertrigo - StatPearls - NCBI Bookshelf (NBK531489) - disease-level clinical article (intertrigo-full.txt) for the indication - verbatim: \"Topical treatments such as mupirocin or bacitracin may be effective for lesions infected with mild bacteria.\" Dose from the same article, the sentence that governs its topical options: \"Topical treatments should be applied twice daily until the rash resolves.\" The 2% strength is the only mupirocin marketed in Egypt.",
      "rationale": "The antibacterial for a fold that has become mildly infected rather than simply macerated. It is the option the source names first, and the one of the two named that is sold plain in Egypt.",
      "cautions": [
        "Re-evaluate rather than repeat if there is no response after 3 to 5 days - the formulary sets that as the point to look again, not to extend the course.",
        "Spreading redness, fever, or a rapidly enlarging area is cellulitis, which the source says needs oral medication. A topical antibiotic does not cover it.",
        "Treat the moisture as well as the infection. An antibacterial applied into a wet fold leaves the cause of the rash exactly where it was."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Applied the same way in children - a topical dose is not weight-based. The formulary's paediatric instruction is a small amount three times daily for 5 to 10 days, with review at 5 days if there is no clinical response (Egyptian National Drug Formulary, mupirocin monograph).",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "BACTROFORM 2% TOP. OINT. 15 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "WESTERN PHARMACEUTICALS INDUSTRIES > WESTERN PHARMA",
          "price_egp": 35.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 15000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "MUPIROCIN SAJA 2% TOP. OINT. 15 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "BIOPHARM EGYPT > SAJA PHARMA",
          "price_egp": 35.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 15000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "MUPIRAX 2% OINT. 10 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "GLOBAL NAPI PHARMACEUTICALS",
          "price_egp": 48.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 10000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "MUPIROCIN SAJA 2% TOP. OINT. 20 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "BIOPHARM EGYPT > SAJA PHARMA",
          "price_egp": 83.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 20000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "MUPIRAX 2% OINT. 30 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "GLOBAL NAPI PHARMACEUTICALS",
          "price_egp": 118.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 30000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "intertrigo"
    },
    {
      "id": 1010,
      "generic": "Flucloxacillin",
      "line": 2,
      "is_adjunct": false,
      "form": "oral.solid",
      "strength_mg": 250.0,
      "adult_dose": "250 mg orally four times daily; the dose may be doubled for a severe infection",
      "adult_duration": "The formulary states no course length for this dose - review at 5 to 7 days rather than repeating a prescription",
      "dose_source": "Intertrigo - StatPearls - NCBI Bookshelf (NBK531489) - disease-level clinical article (intertrigo-full.txt) for the indication - verbatim: \"Flucloxacillin or erythromycin, which targets gram-positive bacteria such as Staphylococcus or Streptococcus, should be prescribed if oral medication is necessary.\" Dose from Egyptian National Drug Formulary - Antimicrobial 2023, flucloxacillin monograph - verbatim: \"The usual adult dose orally or by intramuscular injection is 250 mg four times daily\" and \"All systemic doses may be doubled in severe infections.\"",
      "rationale": "Oral cover when the fold is infected beyond what a cream reaches. Erythromycin is named alongside it in the source and cannot be dispensed in Egypt, which leaves this as the source's usable oral option.",
      "cautions": [
        "No plain flucloxacillin is sold in Egypt. All 33 live products are combinations with amoxicillin or ampicillin, so the patient goes home with a second antibiotic as well - check the pack and account for it.",
        "Penicillin allergy is a contraindication. Ask about prior reactions before prescribing.",
        "Cholestatic jaundice and hepatitis are rare but real, more often with longer courses and in older patients."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Age-banded rather than weight-based by mouth: 1 month to 1 year 62.5 to 125 mg, 2 to 9 years 125 to 250 mg, 10 years and older 250 to 500 mg, all four times daily (Egyptian National Drug Formulary, flucloxacillin monograph, quoting BNFC for beta-lactamase-producing staphylococcal infection including impetigo and cellulitis).",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "FLUMOCIN 250MG 12CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "UP PHARMA",
          "price_egp": 6.2,
          "pack_count": 12,
          "unit_price": 0.52,
          "strength_mg": 250.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": "amoxicillin"
        },
        {
          "trade_name": "AMOFLUX 125/125MG 12 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "RAMEDA > DELTA PHARMA",
          "price_egp": 8.25,
          "pack_count": 12,
          "unit_price": 0.69,
          "strength_mg": 125.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": "amoxicillin"
        },
        {
          "trade_name": "FLUCAMOX 250MG 12CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "SEDICO",
          "price_egp": 8.25,
          "pack_count": 12,
          "unit_price": 0.69,
          "strength_mg": 250.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": "amoxicillin"
        },
        {
          "trade_name": "FLUMOCIN 500MG 8 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "UP PHARMA",
          "price_egp": 6.0,
          "pack_count": 8,
          "unit_price": 0.75,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": "amoxicillin"
        },
        {
          "trade_name": "CURAFLUX 125/125 MG 12 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "RAMEDA > PIONEER",
          "price_egp": 12.5,
          "pack_count": 12,
          "unit_price": 1.04,
          "strength_mg": 125.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": "amoxicillin"
        },
        {
          "trade_name": "AMOFLUX 250/250MG 16 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "RAMEDA > PIONEER",
          "price_egp": 18.0,
          "pack_count": 16,
          "unit_price": 1.12,
          "strength_mg": 250.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": "amoxicillin"
        },
        {
          "trade_name": "HI-FLUCIL 250/250MG 16 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "CID",
          "price_egp": 20.0,
          "pack_count": 16,
          "unit_price": 1.25,
          "strength_mg": 250.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": "amoxicillin"
        },
        {
          "trade_name": "AMPIFLUX 500 MG 12 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "PHARCO",
          "price_egp": 16.0,
          "pack_count": 12,
          "unit_price": 1.33,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": "ampicillin"
        }
      ],
      "condition_id": "intertrigo"
    },
    {
      "id": 1011,
      "generic": "Fluconazole",
      "line": 2,
      "is_adjunct": false,
      "form": "oral.solid",
      "strength_mg": 150.0,
      "adult_dose": "100 to 200 mg orally once daily",
      "adult_duration": "7 days",
      "dose_source": "Intertrigo - StatPearls - NCBI Bookshelf (NBK531489) - disease-level clinical article (intertrigo-full.txt) - verbatim, indication and dose in one sentence: \"For resistant fungal infections, oral fluconazole at a dosage of 100 to 200 mg daily for 7 days may be effective.\"",
      "rationale": "For candidal intertrigo that has not settled on a topical antifungal. The source offers it for resistant fungal infection, which makes it a second step rather than a first.",
      "cautions": [
        "Only after a topical antifungal has been tried. The source reserves oral fluconazole for resistant fungal infection.",
        "Fluconazole inhibits CYP2C9 and CYP3A4 and has multiple drug interactions - check the patient's other medicines, particularly warfarin and statins.",
        "Avoid in pregnancy.",
        "Recurrent or difficult intertrigo is a reason to check a fasting blood glucose. The source asks for it in exactly these patients."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "The source states this 7-day course for adults and gives no weight-based equivalent, so none is stated here.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "JENFUNGA 150 MG 1 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EGPI > JENIKO MEDICINE PHARMACEUTICALS",
          "price_egp": 4.5,
          "pack_count": 1,
          "unit_price": 4.5,
          "strength_mg": 150.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "AMRIFLUCAN 150 MG 2 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "AMRIYA",
          "price_egp": 11.0,
          "pack_count": 2,
          "unit_price": 5.5,
          "strength_mg": 150.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "FLUDCONRIZOLE 150 MG 1 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "RIVA PHARMA S.A.E.",
          "price_egp": 6.0,
          "pack_count": 1,
          "unit_price": 6.0,
          "strength_mg": 150.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "FLUCORAL 150 MG 4 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "SEDICO",
          "price_egp": 60.0,
          "pack_count": 4,
          "unit_price": 15.0,
          "strength_mg": 150.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "TRICONAL 150 MG 1 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "T3A PHARMA > PAXAL",
          "price_egp": 26.5,
          "pack_count": 1,
          "unit_price": 26.5,
          "strength_mg": 150.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "NAVILUCA 150 MG 2 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "INTERNATIONAL DRUG INDUSTRIES > ROTABIOGEN",
          "price_egp": 69.0,
          "pack_count": 2,
          "unit_price": 34.5,
          "strength_mg": 150.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "NAZOWELL 150 MG 3 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EGPI > HEALTH WELL",
          "price_egp": 108.0,
          "pack_count": 3,
          "unit_price": 36.0,
          "strength_mg": 150.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "DIFLUCAN 150 MG 1 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "PFIZER",
          "price_egp": 111.0,
          "pack_count": 1,
          "unit_price": 111.0,
          "strength_mg": 150.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "DIFLUNAZOLE 25MG/5ML SYRUP 70ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "CID",
          "price_egp": 28.8,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 25.0,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "FLUCAZONIL 25MG/5ML SYRUP 70 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EL NILE.",
          "price_egp": 28.8,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 25.0,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "intertrigo"
    },
    {
      "id": 1012,
      "generic": "Hydrocortisone",
      "line": 2,
      "is_adjunct": true,
      "form": "topical",
      "strength_mg": null,
      "adult_dose": "Apply 1% cream sparingly to the affected skin two or three times daily after gently cleansing the area",
      "adult_duration": "Short course only - the label limits courses in children to seven to ten days",
      "dose_source": "Hydrocortisone Cream 1% w/w SmPC sections 4.1 and 4.2 (eMC product 13103) - verbatim indication, which names this condition: \"Hydrocortisone Cream is indicated for the treatment of eczema and dermatitis of all types, including atopic eczema, photodermatitis, otitis externa, primary irritant and allergic dermatitis, intertrigo, prurigo nodularis, seborrhoeic dermatitis and insect bite reactions.\" Dose, verbatim: \"Adults and children: To be applied sparingly to the affected skin two or three times daily after gently cleansing the area. Courses of treatment in children should generally be limited to not more than seven to ten days.\" Clinical framing from Intertrigo - StatPearls - NCBI Bookshelf (NBK531489) - disease-level clinical article (intertrigo-full.txt) - verbatim: \"Low-dose steroids, such as hydrocortisone cream, can be considered for their anti-inflammatory properties, although they are not always necessary.\"",
      "rationale": "An add-on for the itch and redness while something else treats the cause. The source is explicit that it is optional, and its licence names intertrigo directly.",
      "cautions": [
        "Keep the steroid weak and the course short. The source asks for a lower-strength steroid to prevent atrophy in the already thinner epidermis of the flexural surfaces, and prolonged use there causes atrophy and striae.",
        "Buy hydrocortisone acetate 1%, which is what the quoted label covers. Egyptian pharmacies also stock hydrocortisone butyrate - a different ester that the quoted label does not cover - and its 0.1% pack is not a weaker version of a 1% cream, because the percentage on the box does not compare across two different esters.",
        "A steroid alone treats the inflammation and not the organism. Give it alongside the antifungal or antibacterial, never instead of one."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Same application in children, but the label caps the course at seven to ten days.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "NOVACORTIN 1% CREAM 15 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "PHAROPHARMA",
          "price_egp": 4.75,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 15000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "NOVACORTIN 1% OINT. 15 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "PHAROPHARMA",
          "price_egp": 4.75,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 15000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "MICORT 1% CREAM 20 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MISR",
          "price_egp": 12.5,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 20000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "HYDROCORTISONE 1% OINT. 20 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MISR",
          "price_egp": 21.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 20000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "EFFICORT 0.1% LIPOCREAM 15 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MINA PHARM > LABORATOIRES GALDERMA FRANCE",
          "price_egp": 8.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 15000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "intertrigo"
    }
  ]
}