{ "schema_version": 1, "kind": "condition", "id": "low-back-pain", "name": "Acute non-specific low back pain", "category": "chronic", "sources": "Egyptian Drug Authority (EDA) Prescribing Information · Ibuprofen 400 mg film-coated tablets SmPC section 4.2 Posology and method of administration (eMC product 7020)", "review_status": "reviewed", "verified_against": "Egyptian Drug Authority (EDA) Prescribing Information · Ibuprofen 400 mg film-coated tablets SmPC section 4.2 Posology and method of administration (eMC product 7020) · Acute non-specific low back pain - disease-level clinical article (low-back-pain-clinical.txt)", "verified_date": "2026-08", "treatments": [ { "id": 1092, "generic": "Ibuprofen", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 400.0, "adult_dose": "400 mg orally 3 times daily with food", "adult_duration": "shortest duration needed (up to 1-2 weeks)", "dose_source": "Ibuprofen 400 mg film-coated tablets SmPC section 4.2 Posology and method of administration (eMC product 7020)", "rationale": "NSAID that reduces pain and inflammation through COX inhibition; first-line analgesic for acute non-specific low back pain, used to keep the patient mobile rather than confined to bed rest.", "cautions": [ "Screen for RED FLAGS (cauda equina, fever, weight loss, progressive deficit).", "Encourage remaining active; avoid prolonged bed rest.", "Co-prescribe PPI in elderly or high GI risk patients." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Low back pain in children <16 years requires urgent pediatric evaluation to exclude serious organic etiology (discitis, infection, tumor); routine primary care NSAID management is not recommended.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "DAJUANOFEN 400 MG 20 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "COPAD PHARMA", "price_egp": 5.0, "pack_count": 20, "unit_price": 0.25, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLABU 400MG 10 F.C.TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "DELTA PHARMA", "price_egp": 3.75, "pack_count": 10, "unit_price": 0.38, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NOVA-PROFEN 400MG 30 F.C. TABLETS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI", "price_egp": 12.75, "pack_count": 30, "unit_price": 0.42, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "IBUPROFEN 400 MG 10 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SEDICO", "price_egp": 6.0, "pack_count": 10, "unit_price": 0.6, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MAFO 400 MG 30 F.C.TABS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 42.0, "pack_count": 30, "unit_price": 1.4, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BRUFEN 400 MG 30 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA > ABBOTT LABORATORIES", "price_egp": 78.0, "pack_count": 30, "unit_price": 2.6, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PROFUSOL 400MG 20 S.G CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EUROPEAN EGYPTIAN PHARM. IND.", "price_egp": 31.0, "pack_count": null, "unit_price": null, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ANALGIPROF 400 MG 25 SACHETS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EVA PHARMA", "price_egp": 37.5, "pack_count": null, "unit_price": null, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NOVA-PROFEN 100MG/5ML ORAL SUSP. 100ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI", "price_egp": 2.25, "pack_count": null, "unit_price": null, "strength_mg": 100.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "BRUFEMOL-N SUSP. 60 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 4.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "low-back-pain" }, { "id": 1094, "generic": "Referral & safety-netting (no drug therapy)", "line": 1, "is_adjunct": false, "form": null, "strength_mg": null, "adult_dose": null, "adult_duration": null, "dose_source": "Acute non-specific low back pain - disease-level clinical article (low-back-pain-clinical.txt)", "rationale": "Carries the referral criteria and warning signs for this condition, which apply whichever treatment is chosen.", "cautions": [ "RED FLAG - Nighttime pain, fever, bowel or bladder dysfunction, or progressive neurologic deficits require urgent evaluation and referral." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": null, "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [], "condition_id": "low-back-pain" }, { "id": 1093, "generic": "Methocarbamol + Paracetamol", "line": 2, "is_adjunct": true, "form": "oral.solid", "strength_mg": null, "adult_dose": "1-2 tablets (400 mg methocarbamol / 325 mg paracetamol) 3-4 times daily", "adult_duration": "up to 5 days max", "dose_source": "Egyptian Drug Authority (EDA) Prescribing Information", "rationale": "Included per Egyptian Drug Authority (EDA) prescribing practice as a short-term adjunct for acute severe muscle spasm. NICE NG59 does not name muscle relaxants at all - this is EDA practice alone, not a NICE-supported exception.", "cautions": [ "This is a short-term adjunct for severe painful muscle spasm in acute strain.", "May cause drowsiness and dizziness; caution when driving.", "Avoid alcohol and sedatives during therapy." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Not recommended in pediatric care", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "AWADIST RELAX 20 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "HIGH PERFORMANCE PHARMA (HP PHARMA)", "price_egp": 30.0, "pack_count": 20, "unit_price": 1.5, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLEXPRO EXTRA 20 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP", "price_egp": 46.0, "pack_count": 20, "unit_price": 2.3, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "METHOBAMOL 20 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB CAPS > ORIGINAL GROUP", "price_egp": 46.0, "pack_count": 20, "unit_price": 2.3, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "METHORELAX 30 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA > GENNECS PHARMACEUTICALS", "price_egp": 81.0, "pack_count": 30, "unit_price": 2.7, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "low-back-pain" } ] }