{ "schema_version": 1, "kind": "condition", "id": "lyme-disease", "name": "Lyme Disease", "category": "chronic", "sources": "ICPC-3 (WONCA International Classification of Primary Care, 3rd edition) class AD24.05 - condition scope only, no dose · Lyme Disease - StatPearls - NCBI Bookshelf - https://www.ncbi.nlm.nih.gov/books/NBK431066/ · No dose - referral pathway, no medicine given in primary care · Lyme Disease - StatPearls - NCBI Bookshelf (NBK431066)", "review_status": "reviewed", "verified_against": "No dose - referral pathway, no medicine given in primary care · Lyme Disease - disease-level clinical article (lyme-disease-full.txt)", "verified_date": "2026-08", "treatments": [ { "id": 1098, "generic": "No drug therapy in primary care (Referral & Advice)", "line": 1, "is_adjunct": false, "form": null, "strength_mg": null, "adult_dose": "Tick-borne infection carried by Ixodes ticks, which are not established in Egypt - this is not a locally-acquired disease. If a patient returns from a Lyme-endemic area (Europe/North America) with a tick bite and the characteristic expanding rash, empiric doxycycline is the standard treatment and a GP could reasonably start it while arranging specialist referral.", "adult_duration": "Refer, with advice", "dose_source": "No dose - referral pathway, no medicine given in primary care", "rationale": "Tick-borne infection carried by Ixodes ticks, which are not established in Egypt - this is not a locally-acquired disease. If a patient returns from a Lyme-endemic area (Europe/North America) with a tick bite and the characteristic expanding rash, empiric doxycycline is the standard treatment and a GP could reasonably start it while arranging specialist referral.", "cautions": [ "RED FLAG - Acute Lyme carditis presenting with complete atrioventricular heart block, syncope, or myocarditis: assess urgently and refer.", "Not endemic in Egypt. Relevant to a returning traveller or an imported case; consider the travel history before anything else.", "No medicine is prescribed for this in primary care - this entry is for recognition and referral. Anything given is decided by the service it is referred to.", "RED FLAG - Cardiac (Lyme carditis) and neurologic manifestations require hospital admission or specialist management rather than routine outpatient referral.", "RED FLAG - Erythema migrans (an expanding target-like rash) after a tick bite abroad means starting treatment without waiting for serology, and facial palsy, cardiac conduction abnormalities, or arthritis suggesting disseminated disease needs referral." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Children follow the same pathway: recognise and refer. No primary-care medicine is implied.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [], "condition_id": "lyme-disease" }, { "id": 1099, "generic": "Doxycycline", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 100.0, "adult_dose": "200 mg by mouth once, as a single dose", "adult_duration": "single dose", "dose_source": "Lyme Disease - StatPearls - NCBI Bookshelf (NBK431066)", "rationale": "Egypt is not a Lyme country, so the single dose is for the patient who comes back from travel with a tick bite and no symptoms yet. One dose given early prevents the illness, which is why it belongs in primary care rather than behind a referral.", "cautions": [ "This is prophylaxis only for a bite that meets the article's conditions - the tick identified as the right species, or the bite in a highly endemic area, or the tick attached for a prolonged period. A bite that meets none of them does not need an antibiotic.", "It is for the patient who has no symptoms. Anyone with the spreading rash, fever or joint pain needs a full treatment course, not one tablet.", "Take it with a full glass of water, sitting or standing, and not immediately before lying down, or it can burn the gullet.", "Warn about sunburn - doxycycline makes the skin far more sensitive to sun, which matters in Egypt." ], "peds_mgkg_low": 4.4, "peds_mgkg_high": 4.4, "peds_max_mg": 200.0, "peds_basis": "dose", "peds_unit": "mg", "peds_note": "Children take 4.4 mg/kg as a single dose, never more than 200 mg. A single dose is used at any age.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 44, "high_mg": 44, "capped": false }, { "weight_kg": 20, "low_mg": 88, "high_mg": 88, "capped": false }, { "weight_kg": 30, "low_mg": 132, "high_mg": 132, "capped": false }, { "weight_kg": 40, "low_mg": 176, "high_mg": 176, "capped": false } ], "brands": [ { "trade_name": "FARCODOXIN 100MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 11.0, "pack_count": 10, "unit_price": 1.1, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DOXY M.R.100 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ADWIA", "price_egp": 12.0, "pack_count": 10, "unit_price": 1.2, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "GRANUDOXY 100MG 10 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS > PIERRE FRANCE", "price_egp": 12.0, "pack_count": 10, "unit_price": 1.2, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DOXYDOX 100 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 23.0, "pack_count": 10, "unit_price": 2.3, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DOXYMYCIN 100 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL NILE.", "price_egp": 30.0, "pack_count": 10, "unit_price": 3.0, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TABOCINE 100MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "TABUK PHARMACEUTICAL MANUFACTURING COMPANY > TABUK PHARMA", "price_egp": 46.0, "pack_count": 10, "unit_price": 4.6, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VIBRAMYCIN 100MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PFIZER", "price_egp": 65.0, "pack_count": 10, "unit_price": 6.5, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "lyme-disease" } ] }