{
  "schema_version": 1,
  "kind": "condition",
  "id": "occupational-asthma",
  "name": "Occupational Asthma",
  "category": "chronic",
  "sources": "Egyptian National Drug Formulary - Respiratory 2026 · GINA 2023",
  "review_status": "reviewed",
  "verified_against": "Egyptian National Drug Formulary - Respiratory 2026 · GINA 2023",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 1237,
      "generic": "Salbutamol",
      "line": 1,
      "is_adjunct": false,
      "form": "oral.inhalation",
      "strength_mg": 0.1,
      "adult_dose": "100-200 mcg (1-2 puffs) as needed for acute relief of work-related bronchospasm",
      "adult_duration": "long-term PRN",
      "dose_source": "Egyptian National Drug Formulary - Respiratory 2026 (salbutamol monograph): \"Oral inhalation, one inhalation (100 mcg) or two inhalations up to 4 times a day for persistent symptoms\", metered dose inhaler 0.1 mg/dose; children under 12 years the same, maximum 800 micrograms daily. GINA 2023 is not held in this corpus.",
      "rationale": "Short-acting beta-2 agonist bronchodilator for immediate relief of work-related bronchospasm; removal from the causative workplace agent remains the key intervention, this is rescue symptom control.",
      "cautions": [
        "Complete and early removal from exposure to the workplace sensitizing agent is the key intervention.",
        "Overuse (>2 canisters/year) indicates inadequate controller therapy and increased exacerbation risk."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "100-200 mcg (1-2 puffs) PRN via spacer",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "AEROLIN 100MCG/DOSE INHALER",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EIPICO > 3M HEALTH CARE-U.K.",
          "price_egp": 7.3,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 0.1,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "BUTALIN 100MCG/ACTUATION 200 DOSES",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "JULPHAR",
          "price_egp": 12.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 0.1,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "VENTAL INHALER 100 MCG/DOSE 200 DOSES",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "ARAB DRUG COMPANY (ADCO)",
          "price_egp": 72.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 0.1,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "VIASALMOL 100MCG 200 ACTUATION INHALER",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MDI PHARMA",
          "price_egp": 72.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 0.1,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "VENTOLIN EVOHALER 100MCG/ACTUATION INHALER",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "GLAXO SMITHKLINE",
          "price_egp": 86.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 0.1,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "OPICHESTAL SYRUP 120ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EL-OBOUR",
          "price_egp": 2.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "SALBUTAMOL 2MG/5ML SYRUP 120ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "SEDICO",
          "price_egp": 3.5,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 2.0,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "occupational-asthma"
    },
    {
      "id": 1238,
      "generic": "Beclomethasone dipropionate",
      "line": 1,
      "is_adjunct": false,
      "form": "oral.inhalation",
      "strength_mg": 0.1,
      "adult_dose": "200-400 mcg twice daily inhaled regular maintenance therapy",
      "adult_duration": "long-term",
      "dose_source": "Egyptian National Drug Formulary - Respiratory 2026 (beclomethasone dipropionate monograph), oral inhalation: adults \"The usual starting dose is 200 mcg twice daily\" and \"Severe asthma 400 - 800 mcg/ day in two divided doses\"; children \"The usual starting dose is 100 micrograms twice daily. Depending on the severity of asthma, the daily dose may be increased up to 400 micrograms administered in two to four divided doses\". GINA 2023 is not held in this corpus.",
      "rationale": "Inhaled corticosteroid providing regular anti-inflammatory maintenance control of airway inflammation in occupational asthma while exposure and specialist review are addressed.",
      "cautions": [
        "Rinse mouth with water and spit out after inhalation to prevent oral candidiasis and dysphonia.",
        "Refer for occupational medicine and pulmonology specialist evaluation."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "100-200 mcg twice daily under specialist advice",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "BECLOSONE FORTE INHALER 0.1 MG/DOSE 200 DOSES",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "ARAB DRUG COMPANY (ADCO)",
          "price_egp": 75.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 0.1,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "occupational-asthma"
    }
  ]
}