# Prostate Symptoms (Prostatism / LUTS)

- Category: acute
- Review status: reviewed (every claim checked against a document named on this page)
- Sources: Egyptian National Drug Formulary - cardiovascular.pdf, Tamsulosin monograph (chapter PDF p21) · Egyptian National Drug Formulary - endocrine.pdf, Finasteride monograph (chapter PDF p16) · Ng M, Leslie SW, Baradhi KM. Benign Prostatic Hyperplasia. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. NBK558920.
- Verified date: 2026-08

## Verified against

- Egyptian National Drug Formulary - cardiovascular.pdf, Tamsulosin monograph (chapter PDF p21)
- Egyptian National Drug Formulary - endocrine.pdf, Finasteride monograph (chapter PDF p16)
- Ng M, Leslie SW, Baradhi KM. Benign Prostatic Hyperplasia. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. NBK558920.

## Treatment metadata

- Tamsulosin — oral.solid
- Finasteride — oral.solid

## Complete treatment card

```text
PROSTATE SYMPTOMS (PROSTATISM / LUTS)
Sources: Egyptian National Drug Formulary - cardiovascular.pdf, Tamsulosin monograph (chapter PDF
         p21) · Egyptian National Drug Formulary - endocrine.pdf, Finasteride monograph (chapter PDF
         p16) · Ng M, Leslie SW, Baradhi KM. Benign Prostatic Hyperplasia. In: StatPearls
         [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. NBK558920.
Review status: REVIEWED against 3 sources listed above  (2026-08)

1. TAMSULOSIN                                             [1st line]
   Adult    0.4 mg once daily (modified-release capsule)
   Peds     Adult-only condition - paediatric section not applicable
   Source   Egyptian National Drug Formulary - cardiovascular.pdf, Tamsulosin monograph (chapter PDF
            p21)
   Why      Alpha-blocker first-line for symptomatic relief of benign prostatic obstruction; works
            faster than finasteride, so a reasonable first choice for a Cairo GP.
   Caution  Postural (orthostatic) hypotension can occur, especially with the first dose.
            Floppy iris syndrome can occur during cataract surgery - inform the ophthalmologist that
            the patient is taking tamsulosin.
            Caution when combined with other antihypertensive or PDE5-inhibitor drugs (additive
            hypotension).
            Not indicated for hypertension itself (formulary note)
            RED FLAG - Inability to pass urine (acute retention), blood in the urine, back pain or
            weight loss suggesting prostate cancer, or a very high or rapidly rising PSA.
            Take extra care where there is a history of micturition syncope or of postural
            hypotension, and where a potent CYP3A4 inhibitor (eg, Itraconazole, Ketoconazole) is
            being used concurrently.
   Egypt    NORMIRAMA 0.4 MG 30 CAPS.        EGPI > RAMAPH...    60.00 EGP (2.00/unit)
            TAMSUNORM S.R. 0.4MG 30 CAPS.    RAMEDA              60.00 EGP (2.00/unit)
            TAMSULOSIN 0.4 MG 20 CAPS.       GLAXO SMITHKL...    42.00 EGP (2.10/unit)
            CUREPRO XR 0.4 MG 30 CAPS.       DEBEIKY > KHU...   105.00 EGP (3.50/unit)
            BLOCK ALPHA 0.4 MG MR 30 CAPS.   ADWIA              120.00 EGP (4.00/unit)
            FIRAMAZIN 0.4MG 30 H.G.CAPS.     EVA PHARMA          54.00 EGP
            OMNIC 0.4MG 30 MODIFIED RELEASE CAPS. ASTELLAS PHARMA > MULTIPHARMA           147.00 EGP
            OMNIC OCAS 0.4 MG 30 PROLONGED RELEASE F.C.TAB. ASTELLAS PHARMA INC > MU...   282.00 EGP

2. FINASTERIDE                                            [2nd line]
   Adult    5 mg orally once daily, alone or combined with an alpha-1 blocker x 6 to 12 months
            usually needed to see improvement
   Peds     Adult-only condition - paediatric section not applicable
   Source   Egyptian National Drug Formulary - endocrine.pdf, Finasteride monograph (chapter PDF
            p16)
   Why      Used alone or added to an alpha-blocker for larger prostates or an inadequate response
            to tamsulosin alone; formulary explicitly supports benign prostatic hyperplasia as an
            indication.
   Caution  Pregnant women or women who may become pregnant must not handle crushed or broken
            tablets (teratogenic risk to a male fetus).
            Lowers PSA by roughly half after long-term use - interpret PSA results with this in mind
            and re-double any value when screening for prostate cancer.
            Reduced libido and erectile dysfunction are recognised side effects.
            Mood alterations including depressed mood, depression, and, less frequently, suicidal
            ideation has been reported. Monitor carefully.
            Prostate cancer: When compared to placebo, 5-alpha-reductase inhibitors (5-ARIs) have
            been associated with an increase in the incidence of high-grade prostate cancers.
            Diminished urinary flow: Carefully monitor patients with a large residual urinary volume
            or severely diminished urinary flow for obstructive uropathy; these patients may not be
            candidates for finasteride therapy.
            Finasteride has a slow onset (months) and does not help acute urinary retention.
   Egypt    PROHAIR 1 MG 30 TAB.             SIGMA               24.00 EGP (0.80/unit)
            NOPECIA 1 MG 30 CAPS.            ADWIA               36.00 EGP (1.20/unit)
            MIXOSTERIDE 5 MG 14 F.C. TAB.    SIGMA > PHARM...    30.00 EGP (2.14/unit)
            PROSTAT 5MG 14 F.C. TABS.        CID > OCTOBER...    46.00 EGP (3.29/unit)
            PROSTEC 5 MG 14 F.C.TAB.         SIGMA               47.00 EGP (3.36/unit)
            FINASTURA 5MG 30 F.C.TAB.        GLOBAL NAPI P...   111.00 EGP (3.70/unit)
            PROSTRIDE 5MG 30 CAPS.           ADWIA              183.00 EGP (6.10/unit)
            PROSCAR 5MG 28 F.C. TAB.         MERCK SHARP &...   258.00 EGP (9.21/unit)

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.
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