{
  "schema_version": 1,
  "kind": "condition",
  "id": "pulp-space-infection-of-toe",
  "name": "Pulp Space Infection of the Toe",
  "category": "infectious",
  "sources": "Egyptian National Drug Formulary - antimicrobial-2023.pdf, Flucloxacillin monograph (chapter PDF p361) · Nardi NM, McDonald EJ, Syed HA, et al. Felon. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. NBK430933.",
  "review_status": "reviewed",
  "verified_against": "Egyptian National Drug Formulary - antimicrobial-2023.pdf, Flucloxacillin monograph (chapter PDF p361)",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 1516,
      "generic": "Flucloxacillin",
      "line": 1,
      "is_adjunct": false,
      "form": "oral.solid",
      "strength_mg": null,
      "adult_dose": "250 mg orally (or by intramuscular injection) four times daily; the dose may be doubled for a severe infection.",
      "adult_duration": null,
      "dose_source": "Egyptian National Drug Formulary - antimicrobial-2023.pdf, Flucloxacillin monograph (chapter PDF p361)",
      "rationale": "A toe pulp infection is a closed-space staphylococcal soft-tissue infection, matching flucloxacillin's formulary indication for staphylococcal skin and soft-tissue infections; extra caution and a lower referral threshold apply in diabetic patients.",
      "cautions": [
        "Penicillin allergy is a contraindication - ask about prior reactions before prescribing.",
        "A fluctuant abscess needs incision and drainage referral rather than antibiotics alone.",
        "Diabetic patients have a lower threshold for referral given the risk of rapid spread and poor healing in the foot.",
        "Spreading cellulitis or signs of systemic infection need urgent reassessment.",
        "Rare but serious cholestatic jaundice/hepatitis can occur, more often with longer courses and in older patients.",
        "Oral: Take flucloxacillin on an empty stomach. This means 30 to 60 minutes before a meal or snack, or at least 2 hours after."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Paediatric dosing is specialist-set and is not reproduced here.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "FLUMOCIN 250MG 12CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "UP PHARMA",
          "price_egp": 6.2,
          "pack_count": 12,
          "unit_price": 0.52,
          "strength_mg": 250.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": "amoxicillin"
        },
        {
          "trade_name": "AMOFLUX 125/125MG 12 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "RAMEDA > DELTA PHARMA",
          "price_egp": 8.25,
          "pack_count": 12,
          "unit_price": 0.69,
          "strength_mg": 125.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": "amoxicillin"
        },
        {
          "trade_name": "FLUCAMOX 250MG 12CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "SEDICO",
          "price_egp": 8.25,
          "pack_count": 12,
          "unit_price": 0.69,
          "strength_mg": 250.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": "amoxicillin"
        },
        {
          "trade_name": "FLUMOCIN 500MG 8 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "UP PHARMA",
          "price_egp": 6.0,
          "pack_count": 8,
          "unit_price": 0.75,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": "amoxicillin"
        },
        {
          "trade_name": "CURAFLUX 125/125 MG 12 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "RAMEDA > PIONEER",
          "price_egp": 12.5,
          "pack_count": 12,
          "unit_price": 1.04,
          "strength_mg": 125.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": "amoxicillin"
        },
        {
          "trade_name": "AMOFLUX 250/250MG 16 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "RAMEDA > PIONEER",
          "price_egp": 18.0,
          "pack_count": 16,
          "unit_price": 1.12,
          "strength_mg": 250.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": "amoxicillin"
        },
        {
          "trade_name": "HI-FLUCIL 250/250MG 16 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "CID",
          "price_egp": 20.0,
          "pack_count": 16,
          "unit_price": 1.25,
          "strength_mg": 250.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": "amoxicillin"
        },
        {
          "trade_name": "AMPIFLUX 500 MG 12 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "PHARCO",
          "price_egp": 16.0,
          "pack_count": 12,
          "unit_price": 1.33,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": "ampicillin"
        }
      ],
      "condition_id": "pulp-space-infection-of-toe"
    }
  ]
}