{ "schema_version": 1, "kind": "condition", "id": "rabies-prophylaxis", "name": "Post-Exposure Rabies Prophylaxis (Animal Bite)", "category": "infectious", "sources": "Egyptian MOH Rabies Protocol · WHO. Rabies vaccines: WHO position paper - April 2018. Wkly Epidemiol Rec. 2018;93(16):201-220 (who-rabies-position-paper-2018.txt), Administration of rabies vaccines and Table 1 Post-exposure prophylaxis (PEP) by category of exposure · WHO. Rabies vaccines: WHO position paper - April 2018. Wkly Epidemiol Rec. 2018;93(16):201-220 (who-rabies-position-paper-2018.txt), Administration of rabies immunoglobulin", "review_status": "reviewed", "verified_against": "WHO. Rabies vaccines: WHO position paper - April 2018. Wkly Epidemiol Rec. 2018;93(16):201-220 (who-rabies-position-paper-2018.txt), Administration of rabies vaccines and Table 1 Post-exposure prophylaxis (PEP) by category of exposure · WHO. Rabies vaccines: WHO position paper - April 2018. Wkly Epidemiol Rec. 2018;93(16):201-220 (who-rabies-position-paper-2018.txt), Administration of rabies immunoglobulin", "verified_date": "2026-08", "treatments": [ { "id": 1528, "generic": "Rabies vaccine", "line": 1, "is_adjunct": false, "form": "injection", "strength_mg": null, "adult_dose": "IM: 1 full vial (0.5 mL or 1.0 mL depending on product) into deltoid on days 0, 3, 7, and between days 14-28 (4-dose IM regimen); OR ID: 2-site ID (0.1 mL per site, total 0.2 mL per visit) on days 0, 3, and 7 (WHO 1-week ID regimen).", "adult_duration": "Days 0, 3, 7, 14-28", "dose_source": "WHO. Rabies vaccines: WHO position paper - April 2018. Wkly Epidemiol Rec. 2018;93(16):201-220 (who-rabies-position-paper-2018.txt), Administration of rabies vaccines and Table 1 Post-exposure prophylaxis (PEP) by category of exposure", "rationale": "Cell-culture rabies vaccine available in Egyptian MOH anti-rabies centers (VACSERA / fever hospitals)", "cautions": [ "Immediate local wound washing with soap and running water for 15 minutes is critical first step.", "Category III bites (transdermal, mucous contact) require RIG.", "Give IM, NEVER in the gluteal region (reduces antibody response)." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Same dose (1 full vial IM or 2-site 0.1 mL ID) for children as adults: IM into anterolateral thigh in infants <2 years, deltoid in children >=2 years.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "Under 2 years", "age_min_months": 0, "age_max_months": 23, "dose_text": "As for adults (1 full vial IM, or 2-site 0.1 mL intradermal), given intramuscularly into the anterolateral thigh" }, { "label": "2 years and over", "age_min_months": 24, "age_max_months": 216, "dose_text": "As for adults (1 full vial IM, or 2-site 0.1 mL intradermal), given intramuscularly into the deltoid" } ], "peds_doses": null, "brands": [ { "trade_name": "RABIES VACCINE (VERO CELL) 2.5I.U./0.5ML FREEZE-DRIED I.M.INJ.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CHANGCHUM CHANGSHENG LIFE SCIENCES-CHINA > ACDIMA INTERNATIONAL TRADING", "price_egp": 67.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "RABIPUR 2.5I.U./VIAL (PCEC RABIES VACCINE FOR HUMAN )", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "NOVARTIS > RAMCO", "price_egp": 70.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VERORAB 2.5I.U./0.5ML VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI PASTEUR-FRANCE > ETIMEX-EGYPT", "price_egp": 75.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "RABIES VACCINE", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "VACSERA", "price_egp": 198.4, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "rabies-prophylaxis" }, { "id": 1529, "generic": "Rabies immune globulin (human)", "line": 1, "is_adjunct": true, "form": "injection", "strength_mg": null, "adult_dose": "20 IU/kg (Human RIG) infiltrated into and around all wound sites on Day 0", "adult_duration": "Single dose on Day 0", "dose_source": "WHO. Rabies vaccines: WHO position paper - April 2018. Wkly Epidemiol Rec. 2018;93(16):201-220 (who-rabies-position-paper-2018.txt), Administration of rabies immunoglobulin", "rationale": "Passive immunization for WHO Category III exposures available via VACSERA/MOH centers in Egypt", "cautions": [ "Do NOT exceed calculated dose (may inhibit active vaccine antibody response).", "Do not give after Day 7 of vaccine series (active antibodies already forming)." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "20 IU/kg HRIG (or 40 IU/kg equine RIG) infiltrated in/around wounds; remaining volume IM", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "BERIRAB P 300I.U./2ML I.M INJ.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CSL BEHERING-GMBH -GERMANY > 2S PHARMA GROUP", "price_egp": 480.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BERIRAB P 750I.U./5ML I.M INJ.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CSL BEHERING-GMBH -GERMANY > 2S PHARMA GROUP", "price_egp": 1100.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "rabies-prophylaxis" } ] }