{
  "schema_version": 1,
  "kind": "condition",
  "id": "tic-disorder",
  "name": "Tics (Transient and Provisional Tic Disorder)",
  "category": "chronic",
  "sources": "AAN Practice Guideline: The Treatment of Tics in People with Tourette Syndrome and Chronic Tic Disorders (Neurology 2019)",
  "review_status": "reviewed",
  "verified_against": "AAN Practice Guideline: The Treatment of Tics in People with Tourette Syndrome and Chronic Tic Disorders (Neurology 2019) · Tics (Transient and Provisional Tic Disorder) - disease-level clinical article (tic-disorder-clinical.txt)",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 1725,
      "generic": "No drug therapy in primary care (Reassurance & CBIT Referral)",
      "line": 1,
      "is_adjunct": false,
      "form": null,
      "strength_mg": null,
      "adult_dose": "Explain that tics are common, involuntary, and not deliberate or attention-seeking; that most transient and provisional tics improve or resolve within weeks to months without any treatment; and that drawing attention to the tic (telling the child to stop) usually makes it worse, not better. Refer for habit-reversal therapy / Comprehensive Behavioural Intervention for Tics (CBIT) if tics are causing functional impairment (social, academic, or physical) or if the child and family are motivated to pursue active treatment even without impairment. Screen for coexisting ADHD and obsessive-compulsive symptoms, which are common alongside tics and often cause more day-to-day difficulty than the tics themselves.",
      "adult_duration": "Watchful waiting while there is no functional impairment; refer sooner if tics are impairing or the diagnosis is uncertain. The guideline sets no review interval - it requires periodic re-evaluation of medication, not of watching",
      "dose_source": "AAN Practice Guideline: The Treatment of Tics in People with Tourette Syndrome and Chronic Tic Disorders (Neurology 2019)",
      "rationale": "This guideline states that clinicians should inform patients and caregivers that watchful waiting is an acceptable approach in people who do not experience functional impairment from their tics - the situation for most transient and provisional tics - and that CBIT (built on habit-reversal training) should be offered as an initial treatment option relative to medication where it is available. Medication - alpha-agonists such as clonidine or guanfacine, or antipsychotics such as risperidone, aripiprazole, haloperidol, or pimozide - is reserved in this guideline for more troublesome, persistent, or Tourette-spectrum tics, needs baseline and ongoing cardiac and metabolic monitoring, and is a specialist-initiated decision. It is deliberately not listed as a treatment option in this entry for that reason - this entry covers the primary-care presentation, which is transient or provisional (under 12 months), not chronic or Tourette-spectrum tics.",
      "cautions": [
        "Do not start an antipsychotic or an alpha-2 agonist for tics in primary care. Note this is our position, not the guideline's - the AAN says physicians should prescribe alpha-2 agonists, and may prescribe antipsychotics, where benefit outweighs risk, and restricts neither to specialists. The reason to hold back here is monitoring: these drugs need baseline and repeat cardiac and metabolic checks that a Cairo clinic cannot reliably arrange, and behavioural therapy comes first in the guideline anyway.",
        "Refer for urgent assessment if the movement does not fit the usual tic pattern - for example, strictly one-sided, painful, associated with loss of a previously acquired skill, weakness, or altered consciousness. A typical tic is briefly suppressible and often preceded by a premonitory urge; a presentation without those features needs a different work-up.",
        "Screen for comorbid ADHD and obsessive-compulsive symptoms - both are common alongside tics and often cause more functional impairment than the tics themselves, so a missed comorbidity can matter more than the tic itself.",
        "Avoid drawing repeated attention to the tic in front of the child (telling them to stop, pointing it out) - this typically increases tic frequency rather than reducing it.",
        "The guideline's own priority: offer CBIT as the initial treatment ahead of medication where it is available (rec 7b), and assess for comorbid ADHD (3a) and OCD (4a) in everyone with tics.",
        "RED FLAG - A change in cognition, tics occurring during sleep, or constant movement are red flags that raise concern for alternative neurological diagnoses."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "The great majority of presentations are children roughly 4-10 years old; provisional tic disorder is specifically tics present for under 12 months. Tics lasting beyond 12 months, or any history of vocal plus multiple motor tics together, should be discussed with a paediatrician or paediatric neurologist to consider Tourette syndrome, though the initial primary-care approach is the same.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [],
      "condition_id": "tic-disorder"
    }
  ]
}