# Tinea Versicolor (Pityriasis versicolor)

- Category: infectious
- Review status: reviewed (every claim checked against a document named on this page)
- Sources: BAD Guidelines for Tinea Versicolor 2014 · Nizoral 2% Shampoo SmPC section 4.2 (eMC product 1510) · Egyptian National Drug Formulary, antimicrobial 2023, selenium sulfide monograph, tinea versicolor
- Verified date: 2026-08

## Verified against

- Nizoral 2% Shampoo SmPC section 4.2 (eMC product 1510)
- Egyptian National Drug Formulary, antimicrobial 2023, selenium sulfide monograph, tinea versicolor

## Treatment metadata

- Ketoconazole — topical
- Selenium sulfide — topical

## Complete treatment card

```text
TINEA VERSICOLOR (PITYRIASIS VERSICOLOR)
Sources: BAD Guidelines for Tinea Versicolor 2014 · Nizoral 2% Shampoo SmPC section 4.2 (eMC product
         1510) · Egyptian National Drug Formulary, antimicrobial 2023, selenium sulfide monograph,
         tinea versicolor
Review status: REVIEWED against 2 sources listed above  (2026-08)

IS IT THIS? - reference only, to read alongside your own examination
  SYMPTOMS - what the patient reports (1)
    - Lesions are usually painless or mildly itchy, though itching can become severe in hot, humid
      weather  [itching]
  SIGNS - what you find (7)
    - Lesions appear as multiple sharply bordered, oval, finely scaly patches that may be lighter,
      darker, or reddish, sometimes merging together  [scaling]
    - Scale is often not obvious until the skin is stretched or scraped, which brings it out, known
      as the evoked scale sign
    - Lesions favor the upper trunk and upper arms, with facial involvement more common in children
    - An inverse form favors skin folds, the face, or isolated limb areas and is most common in
      immunocompromised patients
    - A follicular form on the back, torso, and limbs affects hair follicles, causing lighter or
      darker skin around them
    - A papular form shows uniform reddish-brown bumps about 2 to 3 mm across, usually painless and
      on the torso  [papules]
    - A rare atrophying variant produces oval, reddish or ivory lesions with a wrinkled surface,
      often linked to prolonged topical steroid use
  TESTS (5)
    - Diagnosis can often be made from the characteristic appearance alone, without further testing
    - Dermoscopy typically shows fine scale and a contrast halo ring around the lesion
    - KOH microscopy gives a definitive diagnosis, showing grape-like clusters of yeast plus long
      hyphae
    - A stain such as methylene blue or ink blue can be added to the KOH prep to improve visibility
      since KOH alone lacks color contrast
    - Culturing the causative Malassezia yeast is difficult because it needs fastidious growth
      conditions
  IF NOT THIS - what else fits (11)
    - Seborrheic dermatitis tends to be more red with thicker scale and also involves the scalp,
      eyebrows, and nasolabial folds
    - Pityriasis rosea shows a collarette of scale in a fir-tree pattern on the trunk, usually
      preceded by a larger herald patch
    - Erythrasma affects the armpits or groin and glows coral-red under Wood's lamp, unlike tinea
      versicolor
    - Pityriasis alba does not fluoresce under Wood's lamp and mainly affects children with a
      history of atopic dermatitis
    - Secondary syphilis frequently involves the palms and soles, unlike tinea versicolor
    - Tinea corporis by definition spares the feet, groin, face, scalp hair, and beard hair
    - Vitiligo causes complete depigmentation, whereas tinea versicolor only causes partial
      lightening
    - Confluent and reticulated papillomatosis shows scaly hyperpigmented macules merging into a
      net-like pattern on the neck, between the breasts, or upper back
    - Guttate psoriasis produces small, inflamed, drop-shaped scaling plaques on the trunk and upper
      arms, often after a strep infection
    - Mycosis fungoides can present as hypopigmented patches on the trunk and limbs, most often in
      people with darker skin
    - Terra firma-forme dermatosis affects the neck or ankle and, unlike tinea versicolor, wipes off
      with an alcohol swab
  Source  StatPearls "Tinea Versicolor" - disease-level clinical article
  Status  traced to the source above

1. KETOCONAZOLE                                           [1st line]
   Adult    Apply 2% shampoo once daily for 5 days (leave on 5 min before rinsing), or 2% cream 1-2
            times daily for 2-3 weeks x 5 days (shampoo); 2-3 weeks (cream)
   Peds     Children >=12 years: apply shampoo once daily for 5 days
   Source   Nizoral 2% Shampoo SmPC section 4.2 (eMC product 1510)
   Why      Topical azole antifungal active against the lipophilic yeast Malassezia furfur that
            causes pityriasis versicolor; clears the causative organism, though the resulting skin
            discolouration takes months to normalise afterward.
   Caution  Caused by lipophilic yeast Malassezia furfur.
            Inform patient that hypopigmented spots take months to normalize after yeast
            eradication.
            Lather shampoo over entire chest/back and leave on for 5 minutes before washing off.
   Egypt    KONAZOLE 2% CREAM 15 GM          ALFACURE PHAR...     6.00 EGP
            CURAZOLE 2% TOPICAL CREAM 15 GM  EVA PHARMA           7.00 EGP
            KETODERM 2% TOP. CREAM 20 GM     SEDICO               7.00 EGP
            KONAZOLE 2% SHAMPOO 60 ML        ALFACURE PHAR...    12.00 EGP
            KETODERM 2% GEL SHAMPOO 60 GM    SEDICO              18.00 EGP
            WELLOFUNG 2% TOPICAL CREAM 40 GM EGPI > HEALTH...    48.00 EGP
            ZAKAN 2GM/100ML SHAMPOO 60 ML    SIGMA               18.30 EGP
            NIZAPEX 20MG/GM SHAMPOO 80 ML    APEX PHARMA         68.00 EGP

2. SELENIUM SULFIDE                                       [2nd line]
   Adult    Apply 2.5% lotion to the affected skin with a little water, leave 10 minutes, then rinse
            thoroughly; once daily x 7 days
   Peds     Not recommended in infants
   Source   Egyptian National Drug Formulary, antimicrobial 2023, selenium sulfide monograph, tinea
            versicolor
   Why      Antifungal and antiseborrhoeic lotion, an alternative to azole therapy for tinea
            versicolor that is particularly useful for widespread trunk involvement.
   Caution  Avoid contact with eyes, genital mucosa, and inflamed or broken skin.
            Rinse off thoroughly after designated exposure to prevent skin irritation.
            Selenium sulfide is an alternative topical antifungal and antiseborrheic agent for
            widespread trunk involvement.
            Ten minutes, then wash it off. Leaving selenium sulfide on overnight is not a stronger
            course, it is a chemical burn waiting to happen.
   Egypt    TINASEL 2.5 GM CREAM 20 GM       ALFACURE PHAR...     5.00 EGP
            VENEER HAIR SHAMPOO 120 ML       EGYPTIAN COMP...    32.95 EGP
            SELENO CARE HAIR SHAMPOO 150 ML  SIGMA > INTER...    98.00 EGP
            SELENGENA ANTI-DANDRUFF SHAMPOO 120 ML EGYPTIAN CO. FOR COSMETICS (E.C.C...   105.00 EGP
            SELENGENA ANTI-DANDRUFF SHAMPOO 220 ML EGYPTIAN CO. FOR COSMETICS (E.C.C...   165.00 EGP

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.
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