{
  "schema_version": 1,
  "kind": "condition",
  "id": "urinary-frequency-urgency",
  "name": "Urinary frequency or urgency",
  "category": "acute",
  "sources": "EAU Guidelines on Non-neurogenic Male/Female LUTS 2023 · Vesicare 5mg film-coated tablets SmPC section 4.2 (eMC product 5559)",
  "review_status": "reviewed",
  "verified_against": "Vesicare 5mg film-coated tablets SmPC section 4.2 (eMC product 5559)",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 1811,
      "generic": "Solifenacin succinate",
      "line": 2,
      "is_adjunct": false,
      "form": "oral.solid",
      "strength_mg": 5.0,
      "adult_dose": "5 mg once daily, may increase to 10 mg once daily if necessary.",
      "adult_duration": "As directed, long-term maintenance",
      "dose_source": "Vesicare 5mg film-coated tablets SmPC section 4.2 (eMC product 5559)",
      "rationale": "Once infective and metabolic causes are excluded, urinary frequency/urgency reflects overactive bladder, for which solifenacin at the standard licensed starting dose is first-line.",
      "cautions": [
        "New excessive urination with thirst and weight loss suggests undiagnosed diabetes; frequency with blood in the urine needs further urological work-up.",
        "Only after excluding urinary tract infection and new-onset diabetes (both are red flags for this symptom) - antimuscarinics treat overactive bladder, not infection or hyperglycaemia.",
        "CONTRAINDICATED in narrow-angle glaucoma, severe ulcerative colitis, and urinary retention.",
        "Anticholinergic effects include dry mouth, constipation, and blurred vision; use cautiously in older patients because of the risk of confusion and falls."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Safety and efficacy in children have not yet been established. Vesicare should not be used in children.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "NANOFREQ 5 MG 20 F.C. TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MEPACO",
          "price_egp": 37.25,
          "pack_count": 20,
          "unit_price": 1.86,
          "strength_mg": 5.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "IMPRONACIN 5MG 10 F.C. TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "BORG",
          "price_egp": 25.2,
          "pack_count": 10,
          "unit_price": 2.52,
          "strength_mg": 5.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "URGINAFECT 5 MG 20 F.C. TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "FUTURE PHARMACEUTICAL INDUSTRIES (FPI) > UTOPIA",
          "price_egp": 72.0,
          "pack_count": 20,
          "unit_price": 3.6,
          "strength_mg": 5.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "SLOWURGE 5 MG 30 F.C.TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MASH PREMIERE > BIOMED",
          "price_egp": 111.0,
          "pack_count": 30,
          "unit_price": 3.7,
          "strength_mg": 5.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "SOLITRACT 5 MG 30 F.C. TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EVA PHARMA",
          "price_egp": 117.0,
          "pack_count": 30,
          "unit_price": 3.9,
          "strength_mg": 5.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "TORMEEL 5 MG 30 F.C. TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EUROPEAN EGYPTIAN PHARM. IND.",
          "price_egp": 126.0,
          "pack_count": 30,
          "unit_price": 4.2,
          "strength_mg": 5.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "SOFENACIN 5MG 30 F.C. TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MARCYRL PHARMACEUTICAL INDUSTRIES (MPI)",
          "price_egp": 141.0,
          "pack_count": 30,
          "unit_price": 4.7,
          "strength_mg": 5.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "VESICARE 5 MG 30 F.C.TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "ASTELLAS PHARMA > AKHNATON TRADING & DISTRIBUTION",
          "price_egp": 377.0,
          "pack_count": 30,
          "unit_price": 12.57,
          "strength_mg": 5.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "SOFENACIN 1MG/ML ORAL SUSP. 120 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MARCYRL PHARMACEUTICAL INDUSTRIES (MPI)",
          "price_egp": 88.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 1.0,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "URGINAFECT 1MG/ML ORAL SUSP. 150 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "FUTURE PHARMACEUTICAL INDUSTRIES (FPI) > UTOPIA",
          "price_egp": 88.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 1.0,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "urinary-frequency-urgency"
    }
  ]
}