{
  "schema_version": 1,
  "kind": "drug_profile",
  "generic": "acarbose",
  "review_status": "reviewed",
  "origin": "openfda",
  "sections": {
    "adult": [
      {
        "text": "Dosage of acarbose tablets must be individualized on the basis of both effectiveness and tolerance while not exceeding the maximum recommended dose of 100 mg t.i.d.",
        "source": "US FDA label for acarbose (Acarbose), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/acarbose.json",
        "verbatim": true
      },
      {
        "text": "Initial Dosage The recommended starting dosage of acarbose tablets is 25 mg given orally three times daily at the start (with the first bite) of each main meal.",
        "source": "US FDA label for acarbose (Acarbose), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/acarbose.json",
        "verbatim": true
      },
      {
        "text": "This may be achieved by initiating treatment at 25 mg once per day and subsequently increasing the frequency of administration to achieve 25 mg t.i.d.",
        "source": "US FDA label for acarbose (Acarbose), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/acarbose.json",
        "verbatim": true
      }
    ],
    "child": [
      {
        "text": "Safety and effectiveness of acarbose tablets in pediatric patients have not been established.",
        "source": "US FDA label for acarbose (Acarbose), section 'pediatric use', retrieved 2026-08-29",
        "cached_file": "labels/acarbose.json",
        "verbatim": true
      }
    ],
    "renal": [
      {
        "text": "No kidney-impairment dose in this label. Not a statement that none is needed.",
        "source": "Read and found silent: the US FDA label for acarbose (Acarbose), retrieved 2026-08-29",
        "cached_file": "labels/acarbose.json",
        "verbatim": false
      }
    ],
    "hepatic": [
      {
        "text": "No liver-impairment dose in this label. Not a statement that none is needed.",
        "source": "Read and found silent: the US FDA label for acarbose (Acarbose), retrieved 2026-08-29",
        "cached_file": "labels/acarbose.json",
        "verbatim": false
      }
    ],
    "pregnancy": [
      {
        "text": "Teratogenic Effects: Pregnancy Category B.",
        "source": "US FDA label for acarbose (Acarbose), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/acarbose.json",
        "verbatim": true
      },
      {
        "text": "The safety of acarbose tablets in pregnant women has not been established.",
        "source": "US FDA label for acarbose (Acarbose), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/acarbose.json",
        "verbatim": true
      },
      {
        "text": "Reproduction studies have been performed in rats at doses up to 480 mg/kg (corresponding to 9 times the exposure in humans, based on drug blood levels) and have revealed no evidence of impaired fertility or harm to the fetus due to acarbose.",
        "source": "US FDA label for acarbose (Acarbose), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/acarbose.json",
        "verbatim": true
      }
    ],
    "lactation": [
      {
        "text": "A small amount of radioactivity has been found in the milk of lactating rats after administration of radiolabeled acarbose.",
        "source": "US FDA label for acarbose (Acarbose), section 'nursing mothers', retrieved 2026-08-29",
        "cached_file": "labels/acarbose.json",
        "verbatim": true
      },
      {
        "text": "It is not known whether this drug is excreted in human milk.",
        "source": "US FDA label for acarbose (Acarbose), section 'nursing mothers', retrieved 2026-08-29",
        "cached_file": "labels/acarbose.json",
        "verbatim": true
      },
      {
        "text": "Because many drugs are excreted in human milk, acarbose tablets should not be administered to a nursing woman.",
        "source": "US FDA label for acarbose (Acarbose), section 'nursing mothers', retrieved 2026-08-29",
        "cached_file": "labels/acarbose.json",
        "verbatim": true
      }
    ]
  }
}