{
  "schema_version": 1,
  "kind": "drug_profile",
  "generic": "calcitonin",
  "review_status": "reviewed",
  "origin": "openfda",
  "sections": {
    "adult": [
      {
        "text": "Ensure adequate calcium and vitamin D intake ( 2.3 , 2.5 ) 2.1 Paget’s Disease of Bone The recommended dose of calcitonin salmon injection for treatment of symptomatic Paget's disease of bone is 100 International Units (0.5 mL) per day administered subcutaneously or intramuscularly.",
        "source": "US FDA label for calcitonin (Calcitonin Salmon), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/calcitonin.json",
        "verbatim": true
      },
      {
        "text": "If the response remains unsatisfactory after two more days, the dose may be further increased to a maximum of 8 International Units/kg every 6 hours. 2.3 Postmenopausal Osteoporosis The recommended dose of calcitonin salmon injection for treatment of postmenopausal osteoporosis in women greater than 5 years postmenopause is 100 International Units (0.5 mL) per day administered subcutaneously or intramuscularly.",
        "source": "US FDA label for calcitonin (Calcitonin Salmon), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/calcitonin.json",
        "verbatim": true
      },
      {
        "text": "If the volume of calcitonin salmon injection to be injected exceeds 2 mL, intramuscular injection is preferable and the total dose should be distributed across multiple sites of injection.",
        "source": "US FDA label for calcitonin (Calcitonin Salmon), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/calcitonin.json",
        "verbatim": true
      }
    ],
    "child": [
      {
        "text": "Safety and effectiveness in pediatric patients have not been established.",
        "source": "US FDA label for calcitonin (Calcitonin Salmon), section 'pediatric use', retrieved 2026-08-29",
        "cached_file": "labels/calcitonin.json",
        "verbatim": true
      }
    ],
    "renal": [
      {
        "text": "No kidney-impairment dose in this label. Not a statement that none is needed.",
        "source": "Read and found silent: the US FDA label for calcitonin (Calcitonin Salmon), retrieved 2026-08-29",
        "cached_file": "labels/calcitonin.json",
        "verbatim": false
      }
    ],
    "hepatic": [
      {
        "text": "No liver-impairment dose in this label. Not a statement that none is needed.",
        "source": "Read and found silent: the US FDA label for calcitonin (Calcitonin Salmon), retrieved 2026-08-29",
        "cached_file": "labels/calcitonin.json",
        "verbatim": false
      }
    ],
    "pregnancy": [
      {
        "text": "Risk Summary There are no studies with calcitonin salmon injection in pregnant women to inform a drug associated risk for birth defects or miscarriage.",
        "source": "US FDA label for calcitonin (Calcitonin Salmon), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/calcitonin.json",
        "verbatim": true
      },
      {
        "text": "In an animal reproduction study, subcutaneous administration of calcitonin salmon to pregnant rabbits during organogenesis at 4 to 18 times the recommended parenteral human dose caused a decrease in fetal birth weights.",
        "source": "US FDA label for calcitonin (Calcitonin Salmon), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/calcitonin.json",
        "verbatim": true
      },
      {
        "text": "No adverse developmental outcome was observed in the rat with subcutaneous administration of calcitonin salmon at 9 times the recommended human parenteral dose based on body surface area (see D ata ).",
        "source": "US FDA label for calcitonin (Calcitonin Salmon), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/calcitonin.json",
        "verbatim": true
      }
    ],
    "lactation": [
      {
        "text": "Risk Summary There is no information on the presence of calcitonin salmon in human milk, the effects on the breastfed child, or the effects on milk production.",
        "source": "US FDA label for calcitonin (Calcitonin Salmon), section 'nursing mothers', retrieved 2026-08-29",
        "cached_file": "labels/calcitonin.json",
        "verbatim": true
      },
      {
        "text": "Calcitonin has been shown to inhibit lactation in rats.",
        "source": "US FDA label for calcitonin (Calcitonin Salmon), section 'nursing mothers', retrieved 2026-08-29",
        "cached_file": "labels/calcitonin.json",
        "verbatim": true
      },
      {
        "text": "The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for calcitonin salmon injection and any potential adverse effects on the breastfed infant from calcitonin salmon injection or from the underlying maternal condition.",
        "source": "US FDA label for calcitonin (Calcitonin Salmon), section 'nursing mothers', retrieved 2026-08-29",
        "cached_file": "labels/calcitonin.json",
        "verbatim": true
      }
    ]
  }
}