Cefixime

DRUG INFORMATION

  ADULT
    - · Adults: 400 mg daily ( 2.1 ) 2.1 Adults The recommended dose of cefixime is 400
      mg daily.
      Source: US FDA label for cefixime (CEFIXIME), section 'dosage and administration',
      retrieved 2026-08-29
    - This may be given as a 400 mg capsule daily.
      Source: US FDA label for cefixime (CEFIXIME), section 'dosage and administration',
      retrieved 2026-08-29
    - For the treatment of uncomplicated cervical/urethral gonococcal infections, a
      single oral dose of 400 mg is recommended.
      Source: US FDA label for cefixime (CEFIXIME), section 'dosage and administration',
      retrieved 2026-08-29

  CHILD
    - Safety and effectiveness of cefixime in children aged less than six months old
      have not been established. The incidence of gastrointestinal adverse reactions,
      including diarrhea and loose stools, in the pediatric patients receiving the
      suspension, was comparable to the incidence seen in adult patients receiving
      tablets.
      Source: US FDA label for cefixime (CEFIXIME), section 'pediatric use', retrieved
      2026-08-29
    - · Adults: 400 mg daily ( 2.1 ) 2.1 Adults The recommended dose of cefixime is 400
      mg daily. This may be given as a 400 mg capsule daily. For the treatment of
      uncomplicated cervical/urethral gonococcal infections, a single oral dose of 400
      mg is recommended. The capsule may be administered without regard to food. In the
      treatment of infections due to Streptococcus pyogenes , a therapeutic dosage of
      cefixime should be administered for at least 10 days.
      Source: US FDA label for cefixime (CEFIXIME), section 'dosage and administration',
      retrieved 2026-08-29
    - In the treatment of infections due to Streptococcus pyogenes , a therapeutic
      dosage of cefixime should be administered for at least 10 days. 2.2 Pediatric
      Patients (6 months or older) The recommended dose is 8 mg/kg/day of the
      suspension.
      Source: US FDA label for cefixime (CEFIXIME), section 'dosage and administration',
      retrieved 2026-08-29

  RENAL IMPAIRMENT
    - In the treatment of infections due to Streptococcus pyogenes, a therapeutic dosage
      of cefixime should be administered for at least 10 days. 2.3 Renal Impairment
      Normal dose and schedule may be employed in patients with creatinine clearances of
      60 mL/min or greater.
      Source: US FDA label for cefixime (CEFIXIME), section 'dosage and administration',
      retrieved 2026-08-29
    - Neither hemodialysis nor peritoneal dialysis removes significant amounts of drug
      from the body.
      Source: US FDA label for cefixime (CEFIXIME), section 'dosage and administration',
      retrieved 2026-08-29
    - ( 8.5 ) · Renal Impairment: Cefixime may be administered in the presence of
      impaired renal function.
      Source: US FDA label for cefixime (CEFIXIME), section 'use in specific
      populations', retrieved 2026-08-29

  HEPATIC IMPAIRMENT
    - Those at risk include patients with renal or hepatic impairment, or poor
      nutritional state, as well as patients receiving a protracted course of
      antimicrobial therapy, and patients previously stabilized on anticoagulant
      therapy.
      Source: US FDA label for cefixime (CEFIXIME), section 'warnings and cautions',
      retrieved 2026-08-29

  PREGNANCY
    - Pregnancy Category B Pregnancy Category B.
      Source: US FDA label for cefixime (CEFIXIME), section 'pregnancy', retrieved
      2026-08-29
    - Reproduction studies have been performed in mice and rats at doses up to 40 times
      the human dose and have revealed no evidence of harm to the fetus due to cefixime.
      Source: US FDA label for cefixime (CEFIXIME), section 'pregnancy', retrieved
      2026-08-29
    - There are no adequate and well-controlled studies in pregnant women.
      Source: US FDA label for cefixime (CEFIXIME), section 'pregnancy', retrieved
      2026-08-29

  BREASTFEEDING
    - It is not known whether cefixime is excreted in human milk.
      Source: US FDA label for cefixime (CEFIXIME), section 'nursing mothers', retrieved
      2026-08-29
    - Consideration should be given to discontinuing nursing temporarily during
      treatment with this drug.
      Source: US FDA label for cefixime (CEFIXIME), section 'nursing mothers', retrieved
      2026-08-29
    - ( 8.1 ) · Nursing Mothers: Consideration should be given to discontinuing nursing
      temporarily during treatment with cefixime.
      Source: US FDA label for cefixime (CEFIXIME), section 'use in specific
      populations', retrieved 2026-08-29