Doxycycline

DRUG INFORMATION

  ADULT
    - DOSAGE & ADMINISTRATION Take one doxycycline capsule (40 mg) once daily in the
      morning on an empty stomach, preferably at least one hour prior to or two hours
      after meals.
      Source: US FDA label for doxycycline (doxycycline), section 'dosage and
      administration', retrieved 2026-08-29
    - ( 2.2 , 5.9 ) 2.1 General Dosing Information Take One Doxycycline Capsule (40 mg)
      once daily in the morning on an empty stomach, preferably at least one hour prior
      to or two hours after meals.
      Source: US FDA label for doxycycline (doxycycline), section 'dosage and
      administration', retrieved 2026-08-29
    - DOSAGE & ADMINISTRATION Take one doxycycline capsule (40 mg) once daily in the
      morning on an empty stomach, preferably at least one hour prior to or two hours
      after meals. ( 2.1 ) Exceeding the recommended dosage may result in an increased
      incidence of side effects including the development of resistant microorganisms.
      Source: US FDA label for doxycycline (doxycycline), section 'dosage and
      administration', retrieved 2026-08-29

  CHILD
    - Doxycycline capsules should not be used in infants and children less than 8 years
      of age [ see Warnings and Precautions ( 5.1 ) ]. Doxycycline capsules have not
      been studied in children of any age with regard to safety or efficacy, therefore
      use in children is not recommended.
      Source: US FDA label for doxycycline (doxycycline), section 'pediatric use',
      retrieved 2026-08-29

  RENAL IMPAIRMENT
    - ( 5.3 ) • If renal impairment exists, doxycycline capsules doses may need to be
      adjusted to avoid excessive systemic accumulations of the drug and possible liver
      injury.
      Source: US FDA label for doxycycline (doxycycline), section 'warnings and
      cautions', retrieved 2026-08-29
    - If renal impairment exists, even usual oral or parenteral doses may lead to
      excessive systemic accumulations of the drug and possible liver toxicity.
      Source: US FDA label for doxycycline (doxycycline), section 'warnings and
      cautions', retrieved 2026-08-29

  HEPATIC IMPAIRMENT
    - No liver-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for doxycycline (doxycycline),
      retrieved 2026-08-29

  PREGNANCY
    - Risk Summary Doxycycline may cause reversible inhibition of bone growth and
      permanent discoloration of deciduous teeth when administered during the second and
      third trimesters of pregnancy [see Warnings and Precautions ( 5.1 and 5.2 )].
      Source: US FDA label for doxycycline (doxycycline), section 'pregnancy', retrieved
      2026-08-29
    - Available data from published studies have not shown a difference in major birth
      defect risk with doxycycline capsules exposure in the first trimester of pregnancy
      compared to unexposed pregnancies.
      Source: US FDA label for doxycycline (doxycycline), section 'pregnancy', retrieved
      2026-08-29
    - Avoid use of doxycycline capsules during the second and third trimester of
      pregnancy.
      Source: US FDA label for doxycycline (doxycycline), section 'pregnancy', retrieved
      2026-08-29

  BREASTFEEDING
    - Lactation: Breastfeeding is not recommended ( 8.2) 8.1 Pregnancy Risk Summary
      Doxycycline may cause reversible inhibition of bone growth and permanent
      discoloration of deciduous teeth when administered during the second and third
      trimesters of pregnancy [see Warnings and Precautions ( 5.1 and 5.2 )].
      Source: US FDA label for doxycycline (doxycycline), section 'use in specific
      populations', retrieved 2026-08-29
    - Animal Data Results from animal studies indicate that doxycycline crosses the
      placenta and is found in fetal tissues. 8.2 Lactation Risk Summary Based on
      available published data, doxycycline is likely to be present in human breast milk
      but the specific concentration in breast milk is not clear.
      Source: US FDA label for doxycycline (doxycycline), section 'use in specific
      populations', retrieved 2026-08-29
    - There is no information on the effects of doxycycline on the breastfed infant or
      the effects on milk production.
      Source: US FDA label for doxycycline (doxycycline), section 'use in specific
      populations', retrieved 2026-08-29