{
  "schema_version": 1,
  "kind": "drug_profile",
  "generic": "griseofulvin",
  "review_status": "reviewed",
  "origin": "openfda",
  "sections": {
    "adult": [
      {
        "text": "Adults: 0.5 g daily (125 mg four times a day., 250 mg twice a day, or 500 mg/day).",
        "source": "US FDA label for griseofulvin (Griseofulvin), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/griseofulvin.json",
        "verbatim": true
      },
      {
        "text": "Patients with less severe or 300 extensive infections may require less, whereas those with widespread lesions may require a starting dose of 0.75 g to 1.0 g/day.",
        "source": "US FDA label for griseofulvin (Griseofulvin), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/griseofulvin.json",
        "verbatim": true
      },
      {
        "text": "Accurate diagnosis of the infecting organism is essential. Identification should be made either by direct microscopic examination of a mounting of infected tissue in a solution of potassium hydroxide or by culture on an appropriate medium. Medication must be continued until the infecting organism is completely eradicated as indicated by appropriate clinical or laboratory examination.",
        "source": "US FDA label for griseofulvin (Griseofulvin), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/griseofulvin.json",
        "verbatim": true
      }
    ],
    "child": [
      {
        "text": "Safety and effectiveness in pediatric patients 2 years of age and younger have not been established. Safety in pediatric patients older than 2 years of age at dosages greater than 10 mg/kg daily has not been established.",
        "source": "US FDA label for griseofulvin (Griseofulvin), section 'pediatric use', retrieved 2026-08-29",
        "cached_file": "labels/griseofulvin.json",
        "verbatim": true
      },
      {
        "text": "Accurate diagnosis of the infecting organism is essential. Identification should be made either by direct microscopic examination of a mounting of infected tissue in a solution of potassium hydroxide or by culture on an appropriate medium. Medication must be continued until the infecting organism is completely eradicated as indicated by appropriate clinical or laboratory examination.",
        "source": "US FDA label for griseofulvin (Griseofulvin), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/griseofulvin.json",
        "verbatim": true
      },
      {
        "text": "Safety in pediatric patients older than 2 years of age at dosages greater than 10 mg/kg daily has not been established.",
        "source": "US FDA label for griseofulvin (Griseofulvin), section 'pediatric use', retrieved 2026-08-29",
        "cached_file": "labels/griseofulvin.json",
        "verbatim": true
      }
    ],
    "renal": [
      {
        "text": "No kidney-impairment dose in this label. Not a statement that none is needed.",
        "source": "Read and found silent: the US FDA label for griseofulvin (Griseofulvin), retrieved 2026-08-29",
        "cached_file": "labels/griseofulvin.json",
        "verbatim": false
      }
    ],
    "hepatic": [
      {
        "text": "No liver-impairment dose in this label. Not a statement that none is needed.",
        "source": "Read and found silent: the US FDA label for griseofulvin (Griseofulvin), retrieved 2026-08-29",
        "cached_file": "labels/griseofulvin.json",
        "verbatim": false
      }
    ],
    "pregnancy": [
      {
        "text": "Teratogenic Effects: Pregnancy Category X: See CONTRAINDICATIONS and PRECAUTIONS, Drug Interactions .",
        "source": "US FDA label for griseofulvin (Griseofulvin), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/griseofulvin.json",
        "verbatim": true
      },
      {
        "text": "Nursing Mothers: It is not known if griseofulvin is excreted in human milk.",
        "source": "US FDA label for griseofulvin (Griseofulvin), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/griseofulvin.json",
        "verbatim": true
      },
      {
        "text": "Because many drugs are excreted in human milk and because of the potential for tumorigenicity shown for griseofulvin in animal studies (see PRECAUTIONS, Carcinogenesis, Mutagenesis, Impairment of Fertility ), a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.",
        "source": "US FDA label for griseofulvin (Griseofulvin), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/griseofulvin.json",
        "verbatim": true
      }
    ],
    "lactation": [
      {
        "text": "It is not known if griseofulvin is excreted in human milk.",
        "source": "US FDA label for griseofulvin (Griseofulvin), section 'nursing mothers', retrieved 2026-08-29",
        "cached_file": "labels/griseofulvin.json",
        "verbatim": true
      },
      {
        "text": "Because many drugs are excreted in human milk and because of the potential for tumorigenicity shown for griseofulvin in animal studies (see PRECAUTIONS, Carcinogenesis, Mutagenesis, Impairment of Fertility ), a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.",
        "source": "US FDA label for griseofulvin (Griseofulvin), section 'nursing mothers', retrieved 2026-08-29",
        "cached_file": "labels/griseofulvin.json",
        "verbatim": true
      }
    ]
  }
}