Hydroquinone

DRUG INFORMATION

  ADULT
    - DRUG DOSAGE AND ADMINISTRATION A thin layer of Pigment Control Creme (Hydroquinone
      USP, 4%) should be applied to the affected area twice daily or as directed by a
      physician. If no improvement is seen after 8-12 weeks of treatment, use of this
      product should be discontinued. There is no recommended dosage for pediatric
      patients under 12 years of age except under the advice and supervision of a
      physician.
      Source: US FDA label for hydroquinone (ZO Skin Health Pigment Control Program Plus
      Hydroquinone), section 'dosage and administration', retrieved 2026-08-29
    - DRUG DOSAGE AND ADMINISTRATION A thin application of Pigment Control + Blending
      Creme should be applied to the affected area twice daily or as directed by a
      physician. Consult product label for instructions on whether to rub in or not.
      There is no recommendation for children under 12 years of age except under the
      advice and supervision of a physician.
      Source: US FDA label for hydroquinone (ZO Skin Health Pigment Control Program Plus
      Hydroquinone), section 'dosage and administration', retrieved 2026-08-29

  CHILD
    - Safety and effectiveness for pediatric patients below the age of 12 years have not
      been established.
      Source: US FDA label for hydroquinone (ZO Skin Health Pigment Control Program Plus
      Hydroquinone), section 'pediatric use', retrieved 2026-08-29
    - DRUG DOSAGE AND ADMINISTRATION A thin layer of Pigment Control Creme (Hydroquinone
      USP, 4%) should be applied to the affected area twice daily or as directed by a
      physician. If no improvement is seen after 8-12 weeks of treatment, use of this
      product should be discontinued. There is no recommended dosage for pediatric
      patients under 12 years of age except under the advice and supervision of a
      physician.
      Source: US FDA label for hydroquinone (ZO Skin Health Pigment Control Program Plus
      Hydroquinone), section 'dosage and administration', retrieved 2026-08-29
    - DRUG DOSAGE AND ADMINISTRATION A thin application of Pigment Control + Blending
      Creme should be applied to the affected area twice daily or as directed by a
      physician. Consult product label for instructions on whether to rub in or not.
      There is no recommendation for children under 12 years of age except under the
      advice and supervision of a physician.
      Source: US FDA label for hydroquinone (ZO Skin Health Pigment Control Program Plus
      Hydroquinone), section 'dosage and administration', retrieved 2026-08-29

  RENAL IMPAIRMENT
    - No kidney-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for hydroquinone (ZO Skin Health
      Pigment Control Program Plus Hydroquinone), retrieved 2026-08-29

  HEPATIC IMPAIRMENT
    - No liver-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for hydroquinone (ZO Skin Health
      Pigment Control Program Plus Hydroquinone), retrieved 2026-08-29

  PREGNANCY
    - Category C Animal reproduction studies have not been conducted with topical
      hydroquinone.
      Source: US FDA label for hydroquinone (ZO Skin Health Pigment Control Program Plus
      Hydroquinone), section 'pregnancy', retrieved 2026-08-29
    - It is also not known whether topical hydroquinone can cause fetal harm when
      administered to a pregnant woman or can affect reproduction capacity.
      Source: US FDA label for hydroquinone (ZO Skin Health Pigment Control Program Plus
      Hydroquinone), section 'pregnancy', retrieved 2026-08-29
    - Topical hydroquinone should be given to a pregnant woman only if clearly needed.
      Source: US FDA label for hydroquinone (ZO Skin Health Pigment Control Program Plus
      Hydroquinone), section 'pregnancy', retrieved 2026-08-29

  BREASTFEEDING   [ CAUTION ]
    The label allows it only when the benefit is judged to outweigh the risk. Read the
      quote below.
    - It is not known whether this drug is excreted in human milk.
      Source: US FDA label for hydroquinone (ZO Skin Health Pigment Control Program Plus
      Hydroquinone), section 'nursing mothers', retrieved 2026-08-29
    - Because many drugs are excreted in human milk, caution should be exercised when
      topical hydroquinone is administered to a nursing woman.
      Source: US FDA label for hydroquinone (ZO Skin Health Pigment Control Program Plus
      Hydroquinone), section 'nursing mothers', retrieved 2026-08-29