Ivermectin

DRUG INFORMATION

  ADULT
    - Apply to the affected areas of the face once daily. Use a pea-size amount for each
      area of the face (forehead, chin, nose, each cheek) that is affected. Spread as a
      thin layer, avoiding the eyes and lips. Ivermectin cream is not for oral,
      ophthalmic, or intravaginal use. Apply to the affected areas once daily. ( 2 ) Not
      for oral, ophthalmic or intravaginal use. ( 2 )
      Source: US FDA label for ivermectin (IVERMECTIN), section 'dosage and
      administration', retrieved 2026-08-29

  CHILD
    - Safety and effectiveness of Ivermectin cream in pediatric patients have not been
      established.
      Source: US FDA label for ivermectin (IVERMECTIN), section 'pediatric use',
      retrieved 2026-08-29

  RENAL IMPAIRMENT
    - No kidney-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for ivermectin (IVERMECTIN),
      retrieved 2026-08-29

  HEPATIC IMPAIRMENT
    - No liver-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for ivermectin (IVERMECTIN),
      retrieved 2026-08-29

  PREGNANCY
    - Risk Summary The available data on the use of ivermectin, including Ivermectin
      cream, in pregnant women are insufficient to establish a drug- associated risk of
      major birth defects, miscarriage, or adverse maternal or fetal outcomes.
      Source: US FDA label for ivermectin (IVERMECTIN), section 'pregnancy', retrieved
      2026-08-29
    - In animal reproduction studies, ivermectin induced adverse developmental outcomes
      when orally administered to pregnant rats and rabbits during the period of
      organogenesis at doses 1909 or 354 times the maximum recommended human dose
      (MRHD), respectively.
      Source: US FDA label for ivermectin (IVERMECTIN), section 'pregnancy', retrieved
      2026-08-29
    - These orally administered doses were maternally toxic to pregnant rats and
      rabbits.
      Source: US FDA label for ivermectin (IVERMECTIN), section 'pregnancy', retrieved
      2026-08-29

  BREASTFEEDING
    - Risk Summary The presence of ivermectin in human milk following topical
      administration of ivermectin has not been evaluated.
      Source: US FDA label for ivermectin (IVERMECTIN), section 'nursing mothers',
      retrieved 2026-08-29
    - There are no data available regarding the effects of ivermectin on milk
      production.
      Source: US FDA label for ivermectin (IVERMECTIN), section 'nursing mothers',
      retrieved 2026-08-29
    - Published literature suggests that ivermectin was detectable in human milk in 4
      lactating women after a single 150 mcg/kg oral dose of ivermectin.
      Source: US FDA label for ivermectin (IVERMECTIN), section 'nursing mothers',
      retrieved 2026-08-29