{
  "schema_version": 1,
  "kind": "drug_profile",
  "generic": "latanoprost",
  "review_status": "reviewed",
  "origin": "openfda",
  "sections": {
    "adult": [
      {
        "text": "The recommended dosage is one drop in the affected eye(s) once daily in the evening. If one dose is missed, treatment should continue with the next dose as normal. The dosage of latanoprost ophthalmic solution should not exceed once daily; the combined use of two or more prostaglandins, or prostaglandin analogs including latanoprost is not recommended.",
        "source": "US FDA label for latanoprost (Latanoprost), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/latanoprost.json",
        "verbatim": true
      }
    ],
    "child": [
      {
        "text": "Safety and effectiveness in pediatric patients have not been established.",
        "source": "US FDA label for latanoprost (Latanoprost), section 'pediatric use', retrieved 2026-08-29",
        "cached_file": "labels/latanoprost.json",
        "verbatim": true
      }
    ],
    "renal": [
      {
        "text": "No kidney-impairment dose in this label. Not a statement that none is needed.",
        "source": "Read and found silent: the US FDA label for latanoprost (Latanoprost), retrieved 2026-08-29",
        "cached_file": "labels/latanoprost.json",
        "verbatim": false
      }
    ],
    "hepatic": [
      {
        "text": "No liver-impairment dose in this label. Not a statement that none is needed.",
        "source": "Read and found silent: the US FDA label for latanoprost (Latanoprost), retrieved 2026-08-29",
        "cached_file": "labels/latanoprost.json",
        "verbatim": false
      }
    ],
    "pregnancy": [
      {
        "text": "Teratogenic Effects: Pregnancy Category C.",
        "source": "US FDA label for latanoprost (Latanoprost), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/latanoprost.json",
        "verbatim": true
      },
      {
        "text": "Reproduction studies have been performed in rats and rabbits.",
        "source": "US FDA label for latanoprost (Latanoprost), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/latanoprost.json",
        "verbatim": true
      },
      {
        "text": "In rabbits, an incidence of 4 of 16 dams had no viable fetuses at a dose that was approximately 80 times the maximum human dose, and the highest nonembryocidal dose in rabbits was approximately 15 times the maximum human dose.",
        "source": "US FDA label for latanoprost (Latanoprost), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/latanoprost.json",
        "verbatim": true
      }
    ],
    "lactation": [
      {
        "text": "It is not known whether this drug or its metabolites are excreted in human milk.",
        "source": "US FDA label for latanoprost (Latanoprost), section 'nursing mothers', retrieved 2026-08-29",
        "cached_file": "labels/latanoprost.json",
        "verbatim": true
      },
      {
        "text": "Because many drugs are excreted in human milk, caution should be exercised when latanoprost is administered to a nursing woman.",
        "source": "US FDA label for latanoprost (Latanoprost), section 'nursing mothers', retrieved 2026-08-29",
        "cached_file": "labels/latanoprost.json",
        "verbatim": true
      },
      {
        "text": "Latanoprost should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. 8.3 Nursing Mothers It is not known whether this drug or its metabolites are excreted in human milk.",
        "source": "US FDA label for latanoprost (Latanoprost), section 'use in specific populations', retrieved 2026-08-29",
        "cached_file": "labels/latanoprost.json",
        "verbatim": true
      }
    ]
  },
  "verdicts": {
    "lactation": {
      "level": "caution",
      "line": "The label allows it only when the benefit is judged to outweigh the risk. Read the quote below.",
      "set_by": "Set from the label's own words, not from a reading of them: 'caution should be exercised when latanoprost is administered to a nursing'."
    }
  }
}