{
  "schema_version": 1,
  "kind": "drug_profile",
  "generic": "lidocaine",
  "review_status": "reviewed",
  "origin": "openfda",
  "sections": {
    "adult": [
      {
        "text": "For intravenous regional anesthesia, only the 50 mL single-dose vial containing 0.5% Lidocaine Hydrochloride Injection, USP should be used.",
        "source": "US FDA label for lidocaine (Accucaine), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/lidocaine.json",
        "verbatim": true
      },
      {
        "text": "Epidural Anesthesia For epidural anesthesia, only the following available specific products of Lidocaine Hydrochloride Injection by Hospira are recommended: 1%. . . . . . . . . . . . . . . . . . . . 30 mL single-dose teartop vials 1.5%. . . . . . . . . . . . . . . . . . . . . . . 20 mL single-dose ampuls 2%. . . . . . . . . . . . . . . . . . . . . . . . .",
        "source": "US FDA label for lidocaine (Accucaine), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/lidocaine.json",
        "verbatim": true
      },
      {
        "text": "Caudal and Lumbar Epidural Block: As a precaution against the adverse experiences sometimes observed following unintentional penetration of the subarachnoid space, a test dose such as 2−3 mL of 1.5% lidocaine hydrochloride should be administered at least 5 minutes prior to injecting the total volume required for a lumbar or caudal epidural block.",
        "source": "US FDA label for lidocaine (Accucaine), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/lidocaine.json",
        "verbatim": true
      }
    ],
    "child": [
      {
        "text": "Dosages in pediatric patients should be reduced, commensurate with age, body weight and physical condition. See DOSAGE AND ADMINISTRATION .",
        "source": "US FDA label for lidocaine (Accucaine), section 'pediatric use', retrieved 2026-08-29",
        "cached_file": "labels/lidocaine.json",
        "verbatim": true
      },
      {
        "text": "Table 1 (Recommended Dosages) summarizes the recommended volumes and concentrations of Lidocaine Hydrochloride Injection, USP for various types of anesthetic procedures. The dosages suggested in this table are for normal healthy adults and refer to the use of epinephrine-free solutions. When larger volumes are required only solutions containing epinephrine should be used, except in those cases where vasopressor drugs may be contraindicated.",
        "source": "This line points to a numbered table that this card does not show - read that table in the label before you dose. US FDA label for lidocaine (Accucaine), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/lidocaine.json",
        "verbatim": true
      },
      {
        "text": "Adults: For normal healthy adults, the individual maximum recommended dose of lidocaine HCl with epinephrine should not exceed 7 mg/kg (3.5 mg/lb) of body weight and in general it is recommended that the maximum total dose not exceed 500 mg.",
        "source": "US FDA label for lidocaine (Accucaine), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/lidocaine.json",
        "verbatim": true
      }
    ],
    "renal": [
      {
        "text": "No kidney-impairment dose in this label. Not a statement that none is needed.",
        "source": "Read and found silent: the US FDA label for lidocaine (Accucaine), retrieved 2026-08-29",
        "cached_file": "labels/lidocaine.json",
        "verbatim": false
      }
    ],
    "hepatic": [
      {
        "text": "Dosages should be reduced for children and for elderly and debilitated patients and patients with cardiac and/or liver disease.",
        "source": "US FDA label for lidocaine (Accucaine), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/lidocaine.json",
        "verbatim": true
      }
    ],
    "pregnancy": [
      {
        "text": "Reproduction studies have been performed in rats at doses up to 6.6 times the human dose and have revealed no evidence of harm to the fetus caused by lidocaine.",
        "source": "US FDA label for lidocaine (Accucaine), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/lidocaine.json",
        "verbatim": true
      },
      {
        "text": "There are, however, no adequate and well-controlled studies in pregnant women.",
        "source": "US FDA label for lidocaine (Accucaine), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/lidocaine.json",
        "verbatim": true
      },
      {
        "text": "Animal reproduction studies are not always predictive of human response.",
        "source": "US FDA label for lidocaine (Accucaine), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/lidocaine.json",
        "verbatim": true
      }
    ],
    "lactation": [
      {
        "text": "It is not known whether this drug is excreted in human milk.",
        "source": "US FDA label for lidocaine (Accucaine), section 'nursing mothers', retrieved 2026-08-29",
        "cached_file": "labels/lidocaine.json",
        "verbatim": true
      },
      {
        "text": "Because many drugs are excreted in human milk, caution should be exercised when lidocaine is administered to a nursing woman.",
        "source": "US FDA label for lidocaine (Accucaine), section 'nursing mothers', retrieved 2026-08-29",
        "cached_file": "labels/lidocaine.json",
        "verbatim": true
      }
    ]
  },
  "verdicts": {
    "lactation": {
      "level": "caution",
      "line": "The label allows it only when the benefit is judged to outweigh the risk. Read the quote below.",
      "set_by": "Set from the label's own words, not from a reading of them: 'caution should be exercised when lidocaine is administered to a nursing'."
    }
  }
}