Nitroglycerin

DRUG INFORMATION

  ADULT
    - Apply 1 inch of ointment (375 mg of ointment equivalent to 1.5 mg of
      nitroglycerin) intra-anally every 12 hours for up to 3 weeks.
      Source: US FDA label for nitroglycerin (NITROGLYCERIN), section 'dosage and
      administration', retrieved 2026-08-29
    - To obtain a 1.5 mg dose of nitroglycerin, the covered finger is laid alongside the
      1-inch dosing line on the carton.
      Source: US FDA label for nitroglycerin (NITROGLYCERIN), section 'dosage and
      administration', retrieved 2026-08-29
    - Apply 1 inch of ointment (375 mg of ointment equivalent to 1.5 mg of
      nitroglycerin) intra-anally every 12 hours for up to 3 weeks ( 2 ).
      Source: US FDA label for nitroglycerin (NITROGLYCERIN), section 'dosage and
      administration', retrieved 2026-08-29

  CHILD
    - The safety and effectiveness of nitroglycerin ointment, 0.4% in pediatric patients
      under 18 years of age have not been established.
      Source: US FDA label for nitroglycerin (NITROGLYCERIN), section 'pediatric use',
      retrieved 2026-08-29

  RENAL IMPAIRMENT
    - No kidney-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for nitroglycerin (NITROGLYCERIN),
      retrieved 2026-08-29

  HEPATIC IMPAIRMENT
    - No liver-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for nitroglycerin (NITROGLYCERIN),
      retrieved 2026-08-29

  PREGNANCY
    - Pregnancy Category C Animal reproduction and teratogenicity studies have not been
      conducted with nitroglycerin ointment, 0.4%.
      Source: US FDA label for nitroglycerin (NITROGLYCERIN), section 'pregnancy',
      retrieved 2026-08-29
    - Nitroglycerin was not teratogenic when administered by topical or dietary route.
      Source: US FDA label for nitroglycerin (NITROGLYCERIN), section 'pregnancy',
      retrieved 2026-08-29
    - There are no adequate and well-controlled studies in pregnant women.
      Source: US FDA label for nitroglycerin (NITROGLYCERIN), section 'pregnancy',
      retrieved 2026-08-29

  BREASTFEEDING   [ CAUTION ]
    The label allows it only when the benefit is judged to outweigh the risk. Read the
      quote below.
    - It is not known whether nitroglycerin is excreted in human milk.
      Source: US FDA label for nitroglycerin (NITROGLYCERIN), section 'nursing mothers',
      retrieved 2026-08-29
    - Because many drugs are excreted in human milk, caution should be exercised when
      nitroglycerin ointment, 0.4% is administered to a nursing woman.
      Source: US FDA label for nitroglycerin (NITROGLYCERIN), section 'nursing mothers',
      retrieved 2026-08-29
    - The latter finding probably reflects delayed development, thus indicating no clear
      evidence of a potential teratogenic effect of nitroglycerin. 8.3 Nursing Mothers
      It is not known whether nitroglycerin is excreted in human milk.
      Source: US FDA label for nitroglycerin (NITROGLYCERIN), section 'use in specific
      populations', retrieved 2026-08-29