{
  "schema_version": 1,
  "kind": "drug_profile",
  "generic": "sodium chloride",
  "review_status": "reviewed",
  "origin": "openfda",
  "sections": {
    "adult": [
      {
        "text": "As required for irrigation. When used as a diluent, or vehicle for other drugs, the drug manufacturer’s recommendations should be followed. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Solutions should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permits.",
        "source": "US FDA label for sodium chloride (Sodium Chloride), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/sodium-chloride.json",
        "verbatim": true
      }
    ],
    "child": [
      {
        "text": "The safety and effectiveness of 0.9% Sodium Chloride Irrigation USP in pediatric patients have not been established. Its limited use in pediatric patients has been inadequate to fully define proper dosage and limitations for use.",
        "source": "US FDA label for sodium chloride (Sodium Chloride), section 'pediatric use', retrieved 2026-08-29",
        "cached_file": "labels/sodium-chloride.json",
        "verbatim": true
      }
    ],
    "renal": [
      {
        "text": "No kidney-impairment dose in this label. Not a statement that none is needed.",
        "source": "Read and found silent: the US FDA label for sodium chloride (Sodium Chloride), retrieved 2026-08-29",
        "cached_file": "labels/sodium-chloride.json",
        "verbatim": false
      }
    ],
    "hepatic": [
      {
        "text": "No liver-impairment dose in this label. Not a statement that none is needed.",
        "source": "Read and found silent: the US FDA label for sodium chloride (Sodium Chloride), retrieved 2026-08-29",
        "cached_file": "labels/sodium-chloride.json",
        "verbatim": false
      }
    ],
    "pregnancy": [
      {
        "text": "– Teratogenic Effects Animal reproduction studies have not been conducted with 0.9% Sodium Chloride Irrigation USP.",
        "source": "US FDA label for sodium chloride (Sodium Chloride), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/sodium-chloride.json",
        "verbatim": true
      },
      {
        "text": "It is also not known whether 0.9% Sodium Chloride Irrigation USP can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. 0.9% Sodium Chloride Irrigation USP should be given to a pregnant woman only if clearly needed.",
        "source": "US FDA label for sodium chloride (Sodium Chloride), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/sodium-chloride.json",
        "verbatim": true
      }
    ],
    "lactation": [
      {
        "text": "It is not known whether this drug is excreted in human milk.",
        "source": "US FDA label for sodium chloride (Sodium Chloride), section 'nursing mothers', retrieved 2026-08-29",
        "cached_file": "labels/sodium-chloride.json",
        "verbatim": true
      },
      {
        "text": "Because many drugs are excreted in human milk, caution should be exercised when 0.9% Sodium Chloride Irrigation USP is administered to a nursing woman.",
        "source": "US FDA label for sodium chloride (Sodium Chloride), section 'nursing mothers', retrieved 2026-08-29",
        "cached_file": "labels/sodium-chloride.json",
        "verbatim": true
      }
    ]
  },
  "verdicts": {
    "lactation": {
      "level": "caution",
      "line": "The label allows it only when the benefit is judged to outweigh the risk. Read the quote below.",
      "set_by": "Set from the label's own words, not from a reading of them: 'caution should be exercised when 0.9% Sodium Chloride Irrigation USP is administered to a nursing'."
    }
  }
}