Tamoxifen

DRUG INFORMATION

  ADULT
    - For patients with breast cancer, the recommended daily dose is 20 to 40 mg.
      Source: US FDA label for tamoxifen (Tamoxifen Citrate), section 'dosage and
      administration', retrieved 2026-08-29
    - Dosages greater than 20 mg per day should be given in divided doses (morning and
      evening).
      Source: US FDA label for tamoxifen (Tamoxifen Citrate), section 'dosage and
      administration', retrieved 2026-08-29
    - In three single agent adjuvant studies in women, one 10 mg tamoxifen citrate
      tablet was administered two (ECOG and NATO) or three (Toronto) times a day for two
      years.
      Source: US FDA label for tamoxifen (Tamoxifen Citrate), section 'dosage and
      administration', retrieved 2026-08-29

  CHILD
    - No child dose in this label. That usually means untested in children, not
      unsuitable - use a paediatric source.
      Source: Read and found silent: the US FDA label for tamoxifen (Tamoxifen Citrate),
      retrieved 2026-08-29

  RENAL IMPAIRMENT
    - No kidney-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for tamoxifen (Tamoxifen Citrate),
      retrieved 2026-08-29

  HEPATIC IMPAIRMENT
    - No liver-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for tamoxifen (Tamoxifen Citrate),
      retrieved 2026-08-29

  PREGNANCY
    - Nothing on pregnancy in this label. Treat as unknown, not as safe.
      Source: Read and found silent: the US FDA label for tamoxifen (Tamoxifen Citrate),
      retrieved 2026-08-29

  BREASTFEEDING
    - Tamoxifen has been reported to inhibit lactation.
      Source: US FDA label for tamoxifen (Tamoxifen Citrate), section 'nursing mothers',
      retrieved 2026-08-29
    - Two placebo-controlled studies in over 150 women have shown that tamoxifen
      significantly inhibits early postpartum milk production.
      Source: US FDA label for tamoxifen (Tamoxifen Citrate), section 'nursing mothers',
      retrieved 2026-08-29
    - In both studies tamoxifen was administered within 24 hours of delivery for between
      5 and 18 days.
      Source: US FDA label for tamoxifen (Tamoxifen Citrate), section 'nursing mothers',
      retrieved 2026-08-29