Tinidazole

DRUG INFORMATION

  ADULT
    - Trichomoniasis: a single 2 g oral dose taken with food.
      Source: US FDA label for tinidazole (Tindamax), section 'dosage and
      administration', retrieved 2026-08-29
    - Treat sexual partners with the same dose and at the same time ( 2.3 ) Giardiasis:
      Adults: a single 2 g dose taken with food.
      Source: US FDA label for tinidazole (Tindamax), section 'dosage and
      administration', retrieved 2026-08-29
    - Pediatric patients older than three years of age: a single dose of 50 mg/kg (up to
      2 g) with food ( 2.4 ) Amebiasis, Intestinal: Adults: 2 g per day for 3 days with
      food.
      Source: US FDA label for tinidazole (Tindamax), section 'dosage and
      administration', retrieved 2026-08-29

  CHILD
    - Other than for use in the treatment of giardiasis and amebiasis in pediatric
      patients older than three years of age, safety and effectiveness of tinidazole in
      pediatric patients have not been established. Pediatric Administration: For those
      unable to swallow tablets, tinidazole tablets may be crushed in artificial cherry
      syrup, to be taken with food [see Dosage and Administration ( 2.2 )].
      Source: US FDA label for tinidazole (Tindamax), section 'pediatric use', retrieved
      2026-08-29
    - Trichomoniasis: a single 2 g oral dose taken with food. Treat sexual partners with
      the same dose and at the same time ( 2.3 ) Giardiasis: Adults: a single 2 g dose
      taken with food. Pediatric patients older than three years of age: a single dose
      of 50 mg/kg (up to 2 g) with food ( 2.4 ) Amebiasis, Intestinal: Adults: 2 g per
      day for 3 days with food.
      Source: US FDA label for tinidazole (Tindamax), section 'dosage and
      administration', retrieved 2026-08-29
    - Pediatric patients older than three years of age: a single dose of 50 mg/kg (up to
      2 g) with food ( 2.4 ) Amebiasis, Intestinal: Adults: 2 g per day for 3 days with
      food.
      Source: US FDA label for tinidazole (Tindamax), section 'dosage and
      administration', retrieved 2026-08-29

  RENAL IMPAIRMENT
    - In general, dose selection for an elderly patient should be cautious, reflecting
      the greater frequency of decreased hepatic, renal, or cardiac function, and of
      concomitant disease or other drug therapy. 8.6 Renal Impairment Because the
      pharmacokinetics of tinidazole in patients with severe renal impairment (CrCL < 22
      mL/min) are not significantly different from those in healthy subjects, no dose
      adjustments are necessary in these patients.
      Source: US FDA label for tinidazole (Tindamax), section 'use in specific
      populations', retrieved 2026-08-29

  HEPATIC IMPAIRMENT
    - Patients undergoing hemodialysis: If tinidazole is administered on the same day as
      and prior to hemodialysis, it is recommended that an additional dose of tinidazole
      equivalent to one-half of the recommended dose be administered after the end of
      the hemodialysis [see Clinical Pharmacology ( 12.3 )]. 8.7 Hepatic Impairment
      There are no data on tinidazole pharmacokinetics in patients with impaired hepatic
      function.
      Source: US FDA label for tinidazole (Tindamax), section 'use in specific
      populations', retrieved 2026-08-29

  PREGNANCY
    - Teratogenic effects: Pregnancy Category C The use of tinidazole in pregnant
      patients has not been studied.
      Source: US FDA label for tinidazole (Tindamax), section 'pregnancy', retrieved
      2026-08-29
    - Since tinidazole crosses the placental barrier and enters fetal circulation it
      should not be administered to pregnant patients in the first trimester.
      Source: US FDA label for tinidazole (Tindamax), section 'pregnancy', retrieved
      2026-08-29
    - Embryo-fetal developmental toxicity studies in pregnant mice indicated no embryo-
      fetal toxicity or malformations at the highest dose level of 2,500 mg/kg
      (approximately 6.3-fold the highest human therapeutic dose based upon body surface
      area conversions).
      Source: US FDA label for tinidazole (Tindamax), section 'pregnancy', retrieved
      2026-08-29

  BREASTFEEDING
    - Tinidazole is excreted in breast milk in concentrations similar to those seen in
      serum.
      Source: US FDA label for tinidazole (Tindamax), section 'nursing mothers',
      retrieved 2026-08-29
    - Tinidazole can be detected in breast milk for up to 72 hours following
      administration.
      Source: US FDA label for tinidazole (Tindamax), section 'nursing mothers',
      retrieved 2026-08-29
    - Interruption of breast-feeding is recommended during tinidazole therapy and for 3
      days following the last dose.
      Source: US FDA label for tinidazole (Tindamax), section 'nursing mothers',
      retrieved 2026-08-29